SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rha'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 10 LEU A 176
MET A 286
LEU A 190
GLN A 187
HIS A 287
 None
 1.45A 1aqbA-3rhaA:
undetectable		 1aqbA-3rhaA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 11 LEU A  79
ALA A 427
ALA A 437
VAL A 219
LEU A  73
 None
None
FDA  A 483 (-3.3A)
None
None
 1.27A 1hbpA-3rhaA:
undetectable		 1hbpA-3rhaA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 11 LEU A 221
GLY A 215
GLY A  59
ILE A  58
VAL A  42
 None
None
FDA  A 483 (-3.8A)
None
None
 0.92A 1hxwB-3rhaA:
undetectable		 1hxwB-3rhaA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		3 / 3 ASP A 146
LEU A 190
LEU A 186
 None
 0.72A 1ikeA-3rhaA:
undetectable		 1ikeA-3rhaA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 GLY A 441
ASP A 435
GLY A 436
THR A 444
ALA A 443
 None
 1.12A 1jg2A-3rhaA:
undetectable		 1jg2A-3rhaA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		3 / 3 TRP A 386
TYR A 396
LEU A 292
 FDA  A 483 (-3.0A)
FDA  A 483 (-4.3A)
None
 1.09A 1kxhA-3rhaA:
undetectable		 1kxhA-3rhaA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 6 TYR A 396
GLU A  57
ILE A 207
GLY A 174
 FDA  A 483 (-4.3A)
None
None
None
 1.14A 1maaB-3rhaA:
undetectable
1maaD-3rhaA:
undetectable		 1maaB-3rhaA:
23.47
1maaD-3rhaA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		3 / 3 ASP A 146
LEU A 190
LEU A 186
 None
 0.63A 1np1B-3rhaA:
undetectable		 1np1B-3rhaA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 4 ALA A 128
VAL A 189
ALA A 192
HIS A 200
 None
 1.11A 1q23A-3rhaA:
undetectable		 1q23A-3rhaA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 7 THR A 100
SER A  90
PHE A 370
PHE A 107
 None
 1.11A 1qcaA-3rhaA:
undetectable		 1qcaA-3rhaA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 VAL A 231
ILE A 262
GLY A  14
ALA A  15
LEU A 227
 None
None
FDA  A 483 (-3.1A)
None
None
 1.05A 1r9oA-3rhaA:
undetectable		 1r9oA-3rhaA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		6 / 12 GLY A 441
ALA A  22
VAL A  10
ILE A 448
VAL A  13
ILE A  12
 None
None
None
None
FDA  A 483 (-4.8A)
None
 1.46A 2f8gB-3rhaA:
undetectable		 2f8gB-3rhaA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 11 ASN A 110
GLY A  94
ASP A  96
THR A 100
THR A 113
 None
 1.39A 2f9wA-3rhaA:
undetectable
2f9wB-3rhaA:
undetectable		 2f9wA-3rhaA:
20.87
2f9wB-3rhaA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		3 / 3 ARG A 393
GLY A 394
SER A 424
 None
None
FDA  A 483 (-2.5A)
 0.57A 2xctB-3rhaA:
undetectable		 2xctB-3rhaA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 6 LEU A 154
PHE A 150
ILE A 171
THR A 202
 None
 1.03A 3mdrA-3rhaA:
undetectable		 3mdrA-3rhaA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 VAL A 298
VAL A 326
GLY A 341
LEU A 364
TYR A 302
 None
 1.35A 3medA-3rhaA:
undetectable
3medB-3rhaA:
undetectable		 3medA-3rhaA:
20.88
3medB-3rhaA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 GLN A 217
ARG A 238
GLY A  16
ALA A  15
ALA A  38
 None
None
FDA  A 483 (-3.3A)
None
FDA  A 483 (-3.4A)
 1.05A 3sudA-3rhaA:
undetectable		 3sudA-3rhaA:
18.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 LEU A 154
LEU A 169
ILE A 171
ILE A 167
PHE A 317
 None
 1.27A 4a79A-3rhaA:
48.5		 4a79A-3rhaA:
30.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 LEU A 154
LEU A 169
ILE A 171
ILE A 167
PHE A 317
 None
 1.27A 4a79B-3rhaA:
48.9		 4a79B-3rhaA:
30.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 11 LEU A 154
LEU A 169
ILE A 171
ILE A 167
PHE A 317
 None
 1.28A 4a7aA-3rhaA:
48.5		 4a7aA-3rhaA:
30.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		3 / 3 ARG A  39
ASP A 425
GLN A 432
 FDA  A 483 (-3.9A)
None
None
 0.88A 4azsA-3rhaA:
undetectable		 4azsA-3rhaA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 GLY A 174
ILE A 207
VAL A 121
PHE A 150
PHE A 183
 None
 1.22A 4fglA-3rhaA:
undetectable
4fglB-3rhaA:
undetectable		 4fglA-3rhaA:
18.85
4fglB-3rhaA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 11 GLY A 341
ARG A 359
ALA A 348
GLN A 324
PHE A 370
 None
 1.49A 4j4vA-3rhaA:
undetectable		 4j4vA-3rhaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_E_SVRE301_1
(NUCLEOCAPSID PROTEIN)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 10 GLY A 341
ARG A 359
ALA A 348
GLN A 324
PHE A 370
 None
 1.50A 4j4vA-3rhaA:
0.0
4j4vE-3rhaA:
0.0		 4j4vA-3rhaA:
21.62
4j4vE-3rhaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 5 GLN A 217
THR A  46
THR A  21
LEU A  77
 None
FDA  A 483 ( 4.2A)
None
None
 1.22A 4lvcA-3rhaA:
2.4		 4lvcA-3rhaA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 7 TRP A 153
PHE A 150
SER A 149
HIS A 151
 None
 1.11A 4o4dA-3rhaA:
undetectable		 4o4dA-3rhaA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 10 SER A 158
LYS A 119
ALA A 115
THR A 113
ALA A 163
 None
 1.33A 4qvwH-3rhaA:
undetectable
4qvwI-3rhaA:
0.0		 4qvwH-3rhaA:
20.76
4qvwI-3rhaA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 10 SER A 158
LYS A 119
ALA A 115
THR A 113
ALA A 163
 None
 1.32A 4qvwV-3rhaA:
undetectable
4qvwW-3rhaA:
undetectable		 4qvwV-3rhaA:
20.76
4qvwW-3rhaA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 GLY A  44
GLY A  43
GLY A  14
ALA A  15
SER A 271
 FDA  A 483 (-3.1A)
None
FDA  A 483 (-3.1A)
None
None
 0.96A 4rtmA-3rhaA:
undetectable		 4rtmA-3rhaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 11 VAL A 121
PHE A 150
PHE A 183
GLY A 174
ILE A 207
 None
 1.17A 4zvmA-3rhaA:
undetectable
4zvmB-3rhaA:
2.1		 4zvmA-3rhaA:
18.65
4zvmB-3rhaA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		3 / 3 ASN A 166
ASP A  96
GLY A  97
 None
 0.61A 5fctB-3rhaA:
undetectable		 5fctB-3rhaA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 10 GLY A 311
GLY A  88
SER A 313
LEU A 312
TYR A 102
 None
 1.39A 5hwkA-3rhaA:
undetectable		 5hwkA-3rhaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 10 GLY A 311
GLY A  88
SER A 313
LEU A 312
TYR A 102
 None
 1.40A 5hwkB-3rhaA:
undetectable		 5hwkB-3rhaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 MET A 175
ALA A 192
HIS A 200
ALA A 195
PHE A 206
 None
 1.16A 5k9dA-3rhaA:
undetectable		 5k9dA-3rhaA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		3 / 3 THR A 392
PRO A 266
ASP A 425
 FDA  A 483 ( 4.8A)
FDA  A 483 ( 4.5A)
None
 0.59A 5l8dB-3rhaA:
undetectable		 5l8dB-3rhaA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 11 ALA A 192
ALA A 188
GLY A 132
ALA A 128
TYR A 431
 None
 0.93A 5lf3K-3rhaA:
undetectable
5lf3L-3rhaA:
undetectable		 5lf3K-3rhaA:
19.13
5lf3L-3rhaA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 11 ALA A 192
ALA A 188
GLY A 132
ALA A 128
TYR A 431
 None
 0.94A 5lf3Y-3rhaA:
undetectable
5lf3Z-3rhaA:
undetectable		 5lf3Y-3rhaA:
19.13
5lf3Z-3rhaA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 4 GLN A 217
THR A  46
THR A  21
LEU A  77
 None
FDA  A 483 ( 4.2A)
None
None
 1.26A 5m5kA-3rhaA:
2.5		 5m5kA-3rhaA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 4 GLN A 217
THR A  46
THR A  21
LEU A  77
 None
FDA  A 483 ( 4.2A)
None
None
 1.26A 5m5kC-3rhaA:
undetectable		 5m5kC-3rhaA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 4 GLN A 217
THR A  46
THR A  21
LEU A  77
 None
FDA  A 483 ( 4.2A)
None
None
 1.23A 5m66B-3rhaA:
2.3		 5m66B-3rhaA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 8 GLY A 168
ALA A 163
PHE A 150
PHE A 198
 None
 0.88A 5mvsB-3rhaA:
undetectable		 5mvsB-3rhaA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		3 / 3 THR A 392
PRO A 266
ASP A 425
 FDA  A 483 ( 4.8A)
FDA  A 483 ( 4.5A)
None
 0.59A 5mwuB-3rhaA:
undetectable		 5mwuB-3rhaA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 8 THR A 315
TYR A 102
PHE A 107
TYR A 327
 None
 1.28A 5v4vA-3rhaA:
undetectable		 5v4vA-3rhaA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 8 THR A 315
TYR A 102
PHE A 107
TYR A 327
 None
 1.30A 5v4vB-3rhaA:
undetectable		 5v4vB-3rhaA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 ALA A 321
ASP A 345
GLY A 173
ALA A 172
LEU A 154
 None
 1.10A 5xxiA-3rhaA:
undetectable		 5xxiA-3rhaA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 ALA A 445
VAL A  35
GLY A  16
ALA A  15
LEU A 227
 None
None
FDA  A 483 (-3.3A)
None
None
 1.05A 5xxiA-3rhaA:
undetectable		 5xxiA-3rhaA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		5 / 12 LEU A 221
GLY A 215
GLY A  59
ILE A  58
VAL A  42
 None
None
FDA  A 483 (-3.8A)
None
None
 0.82A 6dilB-3rhaA:
undetectable		 6dilB-3rhaA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 4 GLN A 217
THR A  46
THR A  21
LEU A  77
 None
FDA  A 483 ( 4.2A)
None
None
 1.20A 6f3mB-3rhaA:
2.4		 6f3mB-3rhaA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		4 / 5 GLN A 217
THR A  46
THR A  21
LEU A  77
 None
FDA  A 483 ( 4.2A)
None
None
 1.20A 6gbnD-3rhaA:
2.3		 6gbnD-3rhaA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3rha PUTRESCINE OXIDASE
(Paenarthrobacter
aurescens) 		3 / 3 TRP A 153
ILE A 123
GLU A 116
 None
 0.75A 6hcxA-3rhaA:
undetectable		 6hcxA-3rhaA:
11.32