SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rhc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3rhc GLUTAREDOXIN-C5,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 PHE A  78
ASN A  76
ILE A  84
GLY A  85
 None
 1.10A 1oniD-3rhcA:
undetectable
1oniF-3rhcA:
undetectable		 1oniD-3rhcA:
21.28
1oniF-3rhcA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3rhc GLUTAREDOXIN-C5,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 THR A  69
ILE A  84
ASN A  76
GLN A  71
 None
 0.93A 2a8tB-3rhcA:
undetectable		 2a8tB-3rhcA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3rhc GLUTAREDOXIN-C5,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 THR A  90
LEU A  99
VAL A  79
VAL A  77
 None
 0.87A 4em2A-3rhcA:
undetectable		 4em2A-3rhcA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 3rhc GLUTAREDOXIN-C5,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLU A 105
MET A 102
LEU A 103
ILE A  84
LEU A  99
 None
 1.19A 4j24D-3rhcA:
undetectable		 4j24D-3rhcA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 3rhc GLUTAREDOXIN-C5,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLU A 105
MET A 102
LEU A 103
ILE A  84
LEU A  99
 None
 1.15A 5toaB-3rhcA:
undetectable		 5toaB-3rhcA:
18.70