SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 3rhf PUTATIVE
POLYPHOSPHATE KINASE
2 FAMILY PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 ALA A 237
LEU A 171
SER A 138
LEU A 119
ILE A 164
 None
 1.02A 1rb3B-3rhfA:
undetectable		 1rb3B-3rhfA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 3rhf PUTATIVE
POLYPHOSPHATE KINASE
2 FAMILY PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 ALA A 237
LEU A 171
GLN A 174
SER A 138
LEU A 119
 None
 1.19A 3ia4A-3rhfA:
undetectable		 3ia4A-3rhfA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_1
(DIHYDROFOLATE
REDUCTASE)		 3rhf PUTATIVE
POLYPHOSPHATE KINASE
2 FAMILY PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 ALA A 237
LEU A 171
GLN A 174
SER A 138
LEU A 119
 None
 1.15A 3ia4C-3rhfA:
undetectable		 3ia4C-3rhfA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3rhf PUTATIVE
POLYPHOSPHATE KINASE
2 FAMILY PROTEIN
(Paenarthrobacter
aurescens) 		3 / 3 GLN A 174
THR A 172
THR A 176
 None
 0.67A 4fu9A-3rhfA:
undetectable		 4fu9A-3rhfA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3rhf PUTATIVE
POLYPHOSPHATE KINASE
2 FAMILY PROTEIN
(Paenarthrobacter
aurescens) 		3 / 3 GLN A 174
THR A 172
THR A 176
 None
 0.65A 4fufA-3rhfA:
undetectable		 4fufA-3rhfA:
18.63