SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rhg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 PHE A 311
LEU A 291
VAL A 277
VAL A 270
 None
 1.14A 1e7aB-3rhgA:
undetectable		 1e7aB-3rhgA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 5 HIS A  23
HIS A 199
HIS A 229
ASP A 294
 ZN  A 367 ( 3.2A)
ZN  A 368 (-3.1A)
ZN  A 368 (-3.2A)
CAC  A 370 (-2.4A)
 0.82A 1e9yB-3rhgA:
15.0		 1e9yB-3rhgA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 6 HIS A  23
HIS A  25
HIS A 199
HIS A 229
ASP A 294
 ZN  A 367 ( 3.2A)
ZN  A 367 ( 3.2A)
ZN  A 368 (-3.1A)
ZN  A 368 (-3.2A)
CAC  A 370 (-2.4A)
 0.80A 1fweC-3rhgA:
15.1		 1fweC-3rhgA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 SER A  31
VAL A  34
ASP A  67
LYS A  49
 None
 1.19A 1hwiB-3rhgA:
undetectable		 1hwiB-3rhgA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 SER A  31
VAL A  34
ASP A  67
LYS A  49
 None
 1.19A 1hwkA-3rhgA:
undetectable		 1hwkA-3rhgA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 SER A  31
VAL A  34
ASP A  67
LYS A  49
 None
 1.20A 1hwkC-3rhgA:
undetectable		 1hwkC-3rhgA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 SER A  31
VAL A  34
ASP A  67
LYS A  49
 None
 1.18A 1hwkD-3rhgA:
undetectable		 1hwkD-3rhgA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 12 TYR A 126
GLU A 166
HIS A 199
HIS A  23
ASP A 294
 UNL  A 372 (-4.3A)
ZN  A 368 (-2.5A)
ZN  A 368 (-3.1A)
ZN  A 367 ( 3.2A)
CAC  A 370 (-2.4A)
 1.01A 1ituA-3rhgA:
15.7		 1ituA-3rhgA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 12 TYR A 126
GLU A 166
HIS A 199
HIS A  23
ASP A 294
 UNL  A 372 (-4.3A)
ZN  A 368 (-2.5A)
ZN  A 368 (-3.1A)
ZN  A 367 ( 3.2A)
CAC  A 370 (-2.4A)
 1.01A 1ituB-3rhgA:
15.8		 1ituB-3rhgA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		3 / 3 ASP A 294
HIS A 229
HIS A  23
 CAC  A 370 (-2.4A)
ZN  A 368 (-3.2A)
ZN  A 367 ( 3.2A)
 0.64A 1oe1A-3rhgA:
undetectable		 1oe1A-3rhgA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		3 / 3 ASP A 294
HIS A 229
HIS A  23
 CAC  A 370 (-2.4A)
ZN  A 368 (-3.2A)
ZN  A 367 ( 3.2A)
 0.65A 1oe3A-3rhgA:
undetectable		 1oe3A-3rhgA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 9 TYR A  63
LEU A 297
ILE A 101
TYR A 126
ILE A 127
 UNL  A 373 ( 3.6A)
None
UNL  A 374 ( 3.7A)
UNL  A 372 (-4.3A)
None
 1.37A 1q6iA-3rhgA:
undetectable		 1q6iA-3rhgA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 12 ALA A  95
GLY A 168
SER A 226
MET A 196
LEU A 214
 ZN  A 367 ( 4.6A)
None
None
None
None
 1.01A 1ya4A-3rhgA:
undetectable		 1ya4A-3rhgA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		3 / 3 ASN A 190
LEU A 186
HIS A 358
 None
 0.79A 2q6fB-3rhgA:
undetectable		 2q6fB-3rhgA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 ILE A 101
SER A 100
ARG A 134
ILE A 167
 UNL  A 374 ( 3.7A)
None
None
None
 1.16A 2q72A-3rhgA:
0.3		 2q72A-3rhgA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		3 / 3 ASP A 294
HIS A 229
HIS A  23
 CAC  A 370 (-2.4A)
ZN  A 368 (-3.2A)
ZN  A 367 ( 3.2A)
 0.66A 2xxgA-3rhgA:
undetectable		 2xxgA-3rhgA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		3 / 3 ASP A 294
HIS A 229
HIS A  23
 CAC  A 370 (-2.4A)
ZN  A 368 (-3.2A)
ZN  A 367 ( 3.2A)
 0.66A 2xxgC-3rhgA:
undetectable		 2xxgC-3rhgA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		3 / 3 ASP A 294
LEU A 257
GLN A  55
 CAC  A 370 (-2.4A)
None
None
 0.79A 3g4lA-3rhgA:
undetectable		 3g4lA-3rhgA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 ASP A 253
SER A 230
ASP A 294
TYR A 126
 None
None
CAC  A 370 (-2.4A)
UNL  A 372 (-4.3A)
 1.21A 3havA-3rhgA:
undetectable		 3havA-3rhgA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		3 / 3 ILE A 105
SER A 123
SER A  98
 None
 0.56A 3iltH-3rhgA:
undetectable		 3iltH-3rhgA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 12 LEU A  81
PHE A  84
ILE A  92
PHE A 296
LEU A  26
 None
None
None
CAC  A 370 (-3.5A)
None
 1.26A 3ko0G-3rhgA:
undetectable
3ko0H-3rhgA:
undetectable
3ko0I-3rhgA:
undetectable
3ko0J-3rhgA:
undetectable		 3ko0G-3rhgA:
13.42
3ko0H-3rhgA:
13.42
3ko0I-3rhgA:
13.42
3ko0J-3rhgA:
13.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RHG_A_BEZA369_0
(PUTATIVE
PHOPHOTRIESTERASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		8 / 10 HIS A 199
HIS A 229
MET A 254
LEU A 257
PHE A 261
GLU A 264
ASP A 294
PHE A 296
 ZN  A 368 (-3.1A)
ZN  A 368 (-3.2A)
BEZ  A 369 ( 3.9A)
None
BEZ  A 369 (-4.3A)
BEZ  A 369 ( 4.4A)
CAC  A 370 (-2.4A)
CAC  A 370 (-3.5A)
 0.58A 3rhgA-3rhgA:
70.6		 3rhgA-3rhgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RHG_A_BEZA369_0
(PUTATIVE
PHOPHOTRIESTERASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		9 / 10 TYR A  63
HIS A 199
TRP A 203
HIS A 229
MET A 254
LEU A 257
PHE A 261
ASP A 294
PHE A 296
 UNL  A 373 ( 3.6A)
ZN  A 368 (-3.1A)
None
ZN  A 368 (-3.2A)
BEZ  A 369 ( 3.9A)
None
BEZ  A 369 (-4.3A)
CAC  A 370 (-2.4A)
CAC  A 370 (-3.5A)
 0.01A 3rhgA-3rhgA:
70.6		 3rhgA-3rhgA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 7 PHE A  27
ALA A 112
THR A 115
LEU A  81
 None
 0.90A 3t3sC-3rhgA:
undetectable		 3t3sC-3rhgA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 TYR A  63
ILE A 101
TYR A 126
ILE A 127
 UNL  A 373 ( 3.6A)
UNL  A 374 ( 3.7A)
UNL  A 372 (-4.3A)
None
 0.90A 3uqbA-3rhgA:
undetectable		 3uqbA-3rhgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 12 ILE A 146
GLY A 165
ILE A 225
ASN A 189
LEU A 181
 None
 1.12A 4a81A-3rhgA:
undetectable		 4a81A-3rhgA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		3 / 3 ASN A 191
ASP A 147
ASN A 151
 None
 0.57A 4agaA-3rhgA:
undetectable		 4agaA-3rhgA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 HIS A  25
GLU A  24
MET A 254
ASP A 253
 ZN  A 367 ( 3.2A)
None
BEZ  A 369 ( 3.9A)
None
 1.30A 4cevA-3rhgA:
undetectable
4cevB-3rhgA:
1.4		 4cevA-3rhgA:
23.82
4cevB-3rhgA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 MET A 254
ASP A 253
HIS A  25
GLU A  24
 BEZ  A 369 ( 3.9A)
None
ZN  A 367 ( 3.2A)
None
 1.30A 4cevA-3rhgA:
undetectable
4cevC-3rhgA:
1.4		 4cevA-3rhgA:
23.82
4cevC-3rhgA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 PHE A  27
ALA A 112
THR A 115
LEU A  81
 None
 1.03A 4ejgD-3rhgA:
undetectable		 4ejgD-3rhgA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 5 HIS A  23
HIS A 199
HIS A 229
ASP A 294
 ZN  A 367 ( 3.2A)
ZN  A 368 (-3.1A)
ZN  A 368 (-3.2A)
CAC  A 370 (-2.4A)
 0.78A 4h9mA-3rhgA:
13.9		 4h9mA-3rhgA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 12 ILE A 164
GLY A  97
GLY A 124
ILE A 154
LEU A 108
 None
 1.00A 4mwzA-3rhgA:
undetectable		 4mwzA-3rhgA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 HIS A 229
ASP A 253
SER A 226
SER A 195
 ZN  A 368 (-3.2A)
None
None
None
 1.20A 4ndnA-3rhgA:
undetectable		 4ndnA-3rhgA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 5 ILE A 101
LEU A  30
ASP A 294
VAL A  77
 UNL  A 374 ( 3.7A)
UNL  A 374 ( 3.6A)
CAC  A 370 (-2.4A)
None
 0.99A 4nkxB-3rhgA:
undetectable		 4nkxB-3rhgA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 7 ASN A 337
LEU A 280
ILE A 330
ILE A 329
 None
 0.83A 4ojbA-3rhgA:
undetectable		 4ojbA-3rhgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 ASN A  82
ILE A  92
ILE A 117
VAL A 119
 None
 0.89A 4olmA-3rhgA:
undetectable		 4olmA-3rhgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 LEU A  30
HIS A 229
HIS A  23
GLU A 166
 UNL  A 374 ( 3.6A)
ZN  A 368 (-3.2A)
ZN  A 367 ( 3.2A)
ZN  A 368 (-2.5A)
 0.98A 4pahA-3rhgA:
undetectable		 4pahA-3rhgA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 LEU A 297
HIS A 229
HIS A  23
GLU A 166
 None
ZN  A 368 (-3.2A)
ZN  A 367 ( 3.2A)
ZN  A 368 (-2.5A)
 0.96A 4pahA-3rhgA:
undetectable		 4pahA-3rhgA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 GLY A 306
GLN A 299
ILE A 259
PHE A 296
 None
None
None
CAC  A 370 (-3.5A)
 1.08A 4qogA-3rhgA:
undetectable
4qogB-3rhgA:
undetectable		 4qogA-3rhgA:
20.16
4qogB-3rhgA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 12 HIS A  23
GLU A 251
HIS A 229
GLU A 166
LEU A 135
 ZN  A 367 ( 3.2A)
None
ZN  A 368 (-3.2A)
ZN  A 368 (-2.5A)
None
 1.06A 4r7lA-3rhgA:
undetectable		 4r7lA-3rhgA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 6 HIS A  23
HIS A  25
HIS A 199
HIS A 229
ASP A 294
 ZN  A 367 ( 3.2A)
ZN  A 367 ( 3.2A)
ZN  A 368 (-3.1A)
ZN  A 368 (-3.2A)
CAC  A 370 (-2.4A)
 0.65A 4ubpC-3rhgA:
14.9		 4ubpC-3rhgA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 7 TYR A 239
ALA A 276
LEU A 250
PHE A 252
 None
 0.90A 4uymA-3rhgA:
undetectable		 4uymA-3rhgA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 7 TYR A 239
ALA A 276
LEU A 250
PHE A 252
 None
 0.88A 4uymB-3rhgA:
undetectable		 4uymB-3rhgA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 5 ILE A 127
ILE A 167
TYR A 126
GLU A 166
 None
None
UNL  A 372 (-4.3A)
ZN  A 368 (-2.5A)
 1.05A 4zzcE-3rhgA:
undetectable		 4zzcE-3rhgA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 HIS A 229
ASP A 253
SER A 226
SER A 195
 ZN  A 368 (-3.2A)
None
None
None
 1.17A 5a1iA-3rhgA:
undetectable		 5a1iA-3rhgA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 12 ILE A  74
ALA A 161
ALA A 121
VAL A 119
GLY A 153
 None
 1.03A 5igjA-3rhgA:
undetectable		 5igjA-3rhgA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		5 / 12 ILE A  74
ALA A 161
ALA A 121
VAL A 119
GLY A 153
 None
 1.03A 5igtA-3rhgA:
undetectable		 5igtA-3rhgA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 5 THR A  96
HIS A  23
ASP A 294
HIS A 229
 None
ZN  A 367 ( 3.2A)
CAC  A 370 (-2.4A)
ZN  A 368 (-3.2A)
 1.00A 6dchA-3rhgA:
undetectable		 6dchA-3rhgA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		3 / 3 LEU A 114
ASP A  94
ILE A 105
 None
 0.65A 6dh0B-3rhgA:
undetectable		 6dh0B-3rhgA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 HIS A 229
ASP A 253
SER A 226
SER A 195
 ZN  A 368 (-3.2A)
None
None
None
 1.13A 6fbnB-3rhgA:
undetectable		 6fbnB-3rhgA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 HIS A 229
ASP A 253
SER A 226
SER A 195
 ZN  A 368 (-3.2A)
None
None
None
 1.16A 6fboA-3rhgA:
undetectable		 6fboA-3rhgA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 8 HIS A 229
ASP A 253
SER A 226
SER A 195
 ZN  A 368 (-3.2A)
None
None
None
 1.22A 6fcbA-3rhgA:
undetectable		 6fcbA-3rhgA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 LEU A  30
HIS A 229
HIS A  23
GLU A 166
 UNL  A 374 ( 3.6A)
ZN  A 368 (-3.2A)
ZN  A 367 ( 3.2A)
ZN  A 368 (-2.5A)
 0.97A 6pahA-3rhgA:
undetectable		 6pahA-3rhgA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 3rhg PUTATIVE
PHOPHOTRIESTERASE
(Proteus
mirabilis) 		4 / 6 LEU A 297
HIS A 229
HIS A  23
GLU A 166
 None
ZN  A 368 (-3.2A)
ZN  A 367 ( 3.2A)
ZN  A 368 (-2.5A)
 0.99A 6pahA-3rhgA:
undetectable		 6pahA-3rhgA:
20.70