SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 10 ALA A  34
ALA A  37
LEU A  27
LEU A 136
SER A  51
 None
 0.83A 2bxgB-3rijA:
undetectable		 2bxgB-3rijA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 12 GLY A 130
GLY A 101
ALA A 100
VAL A  24
LEU A  14
 None
 0.94A 2nyuA-3rijA:
undetectable		 2nyuA-3rijA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_2
(YAEB-LIKE PROTEIN
RPA0152)		 3rij SC_2CX5
(Thermus
thermophilus) 		4 / 5 HIS A 108
ARG A 134
ASP A  99
THR A  96
 None
 1.49A 3okxB-3rijA:
undetectable		 3okxB-3rijA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 11 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.99A 4qvlK-3rijA:
undetectable
4qvlL-3rijA:
undetectable		 4qvlK-3rijA:
23.96
4qvlL-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 11 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.98A 4qvlY-3rijA:
undetectable
4qvlZ-3rijA:
undetectable		 4qvlY-3rijA:
23.96
4qvlZ-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 9 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.98A 4qvmK-3rijA:
undetectable
4qvmL-3rijA:
undetectable		 4qvmK-3rijA:
22.52
4qvmL-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 10 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.98A 4qvmY-3rijA:
undetectable
4qvmZ-3rijA:
undetectable		 4qvmY-3rijA:
22.52
4qvmZ-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 10 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.99A 4qvpK-3rijA:
undetectable
4qvpL-3rijA:
undetectable		 4qvpK-3rijA:
23.96
4qvpL-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 10 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.99A 4qvpY-3rijA:
undetectable
4qvpZ-3rijA:
undetectable		 4qvpY-3rijA:
23.96
4qvpZ-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 11 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.98A 4qw1K-3rijA:
undetectable
4qw1L-3rijA:
undetectable		 4qw1K-3rijA:
22.83
4qw1L-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 10 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.98A 4qw1Y-3rijA:
undetectable
4qw1Z-3rijA:
undetectable		 4qw1Y-3rijA:
22.83
4qw1Z-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 10 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.98A 4qw3K-3rijA:
undetectable
4qw3L-3rijA:
undetectable		 4qw3K-3rijA:
23.96
4qw3L-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 10 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.98A 4qw3Y-3rijA:
undetectable
4qw3Z-3rijA:
undetectable		 4qw3Y-3rijA:
23.96
4qw3Z-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 10 ALA A  60
LEU A  85
LEU A  95
ALA A  87
ALA A  94
 None
 1.19A 4zbrA-3rijA:
undetectable		 4zbrA-3rijA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 11 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.97A 5bxnK-3rijA:
undetectable
5bxnL-3rijA:
undetectable		 5bxnK-3rijA:
23.96
5bxnL-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 11 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.98A 5bxnY-3rijA:
undetectable
5bxnZ-3rijA:
undetectable		 5bxnY-3rijA:
23.96
5bxnZ-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 9 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.99A 5d0xK-3rijA:
undetectable
5d0xL-3rijA:
undetectable		 5d0xK-3rijA:
24.42
5d0xL-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3rij SC_2CX5
(Thermus
thermophilus) 		5 / 9 ALA A  87
ALA A  91
GLY A  56
GLY A  59
ALA A  60
 None
 0.99A 5d0xY-3rijA:
undetectable
5d0xZ-3rijA:
undetectable		 5d0xY-3rijA:
24.42
5d0xZ-3rijA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3rij SC_2CX5
(Thermus
thermophilus) 		4 / 5 TYR A  61
TYR A  54
GLY A  55
GLY A  56
 None
 1.15A 5x7pA-3rijA:
undetectable		 5x7pA-3rijA:
9.57