SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rio'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		5 / 11 ASN A  14
SER A  78
LEU A  74
LEU A  67
LEU A  66
 None
 1.24A 3ndvA-3rioA:
undetectable
3ndvB-3rioA:
undetectable		 3ndvA-3rioA:
19.35
3ndvB-3rioA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		5 / 11 LEU A  67
LEU A  66
ASN A  14
SER A  78
LEU A  74
 None
 1.25A 3ndvA-3rioA:
undetectable
3ndvB-3rioA:
undetectable		 3ndvA-3rioA:
19.35
3ndvB-3rioA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		5 / 11 ASN A  14
SER A  78
LEU A  74
LEU A  67
LEU A  66
 None
 1.25A 3ndvC-3rioA:
undetectable
3ndvD-3rioA:
undetectable		 3ndvC-3rioA:
19.35
3ndvD-3rioA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		5 / 11 LEU A  67
LEU A  66
ASN A  14
SER A  78
LEU A  74
 None
 1.24A 3ndvC-3rioA:
undetectable
3ndvD-3rioA:
undetectable		 3ndvC-3rioA:
19.35
3ndvD-3rioA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		4 / 8 VAL A 140
MET A 143
TYR A  83
ILE A  85
 None
 0.90A 3remA-3rioA:
undetectable		 3remA-3rioA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		4 / 8 VAL A 140
MET A 143
TYR A  83
ILE A  85
 None
 0.90A 3remB-3rioA:
undetectable		 3remB-3rioA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		5 / 12 GLY A  32
GLY A  34
LEU A  11
ASN A  12
GLY A  30
 None
 1.07A 3sglA-3rioA:
undetectable		 3sglA-3rioA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		4 / 7 PHE A  52
ILE A  29
ILE A  85
ALA A 106
 None
 0.84A 6b5vA-3rioA:
undetectable
6b5vC-3rioA:
undetectable		 6b5vA-3rioA:
18.08
6b5vC-3rioA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		4 / 7 PHE A  52
ILE A  29
ILE A  85
ALA A 106
 None
 0.84A 6b5vC-3rioA:
undetectable
6b5vD-3rioA:
undetectable		 6b5vC-3rioA:
18.08
6b5vD-3rioA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		4 / 7 ALA A 106
PHE A  52
ILE A  29
ILE A  85
 None
 0.84A 6b5vB-3rioA:
2.2
6b5vD-3rioA:
undetectable		 6b5vB-3rioA:
18.08
6b5vD-3rioA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		5 / 10 MET A 143
LEU A 152
GLU A 156
ILE A  85
HIS A  84
 None
 1.43A 6cbzB-3rioA:
undetectable		 6cbzB-3rioA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		4 / 5 ILE A  77
SER A  78
ALA A 108
LEU A 150
 None
 1.03A 6dwnA-3rioA:
undetectable		 6dwnA-3rioA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3rio PTSGHI OPERON
ANTITERMINATOR
(Bacillus
subtilis) 		5 / 9 LEU A  66
PHE A  63
LEU A  54
VAL A  75
ASN A  79
 None
 1.44A 6ftpA-3rioA:
undetectable
6ftpB-3rioA:
undetectable		 6ftpA-3rioA:
15.93
6ftpB-3rioA:
10.56