SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rjd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 3rjd HIGH AFFINITY
IMMUNOGLOBULIN GAMMA
FC RECEPTOR I
(Homo
sapiens) 		3 / 3 GLU A 118
SER A 110
VAL A 109
 None
 0.56A 3eeoA-3rjdA:
undetectable		 3eeoA-3rjdA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3rjd HIGH AFFINITY
IMMUNOGLOBULIN GAMMA
FC RECEPTOR I
(Homo
sapiens) 		4 / 7 VAL A 269
ILE A 160
THR A 184
GLY A 117
 None
None
NAG  A 369 ( 4.7A)
None
 0.90A 3gssB-3rjdA:
undetectable		 3gssB-3rjdA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 3rjd HIGH AFFINITY
IMMUNOGLOBULIN GAMMA
FC RECEPTOR I
(Homo
sapiens) 		5 / 12 SER A 255
LEU A 278
GLN A 246
VAL A 208
LEU A 202
 None
 1.27A 5ubbA-3rjdA:
undetectable		 5ubbA-3rjdA:
20.66