SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rjl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.43A 1p6jA-3rjlA:
undetectable
1p6jB-3rjlA:
undetectable		 1p6jA-3rjlA:
22.64
1p6jB-3rjlA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.43A 1p6jA-3rjlA:
undetectable
1p6jB-3rjlA:
undetectable		 1p6jA-3rjlA:
22.64
1p6jB-3rjlA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		3 / 3 LYS A 496
ASP A 292
ASN A 468
 None
 0.86A 2bm9A-3rjlA:
3.0		 2bm9A-3rjlA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		5 / 10 VAL A 177
ILE A 179
LEU A  40
GLY A 237
ALA A  71
 None
 1.23A 2xf3A-3rjlA:
undetectable		 2xf3A-3rjlA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B500_1
(ORF12)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		5 / 9 VAL A 177
ILE A 179
LEU A  40
GLY A 237
ALA A  71
 None
 1.23A 2xf3B-3rjlA:
undetectable		 2xf3B-3rjlA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 8 VAL A 177
LEU A  40
GLY A 237
ALA A  71
 None
 0.75A 2xfsA-3rjlA:
undetectable		 2xfsA-3rjlA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		5 / 9 VAL A 177
ILE A 179
LEU A  40
GLY A 237
ALA A  71
 None
 1.23A 2xfsB-3rjlA:
undetectable		 2xfsB-3rjlA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 8 VAL A 177
LEU A  40
GLY A 237
ALA A  71
 None
 0.73A 2xh9A-3rjlA:
undetectable		 2xh9A-3rjlA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1436_1
(ORF12)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		5 / 9 VAL A 177
ILE A 179
LEU A  40
GLY A 237
ALA A  71
 None
 1.24A 2xh9B-3rjlA:
undetectable		 2xh9B-3rjlA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 485
GLY A 477
ASP A 292
TYR A 470
 None
 1.08A 3aruA-3rjlA:
undetectable		 3aruA-3rjlA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 SER A  55
LYS A 126
LEU A 120
ALA A 124
 None
 0.98A 3cfqA-3rjlA:
undetectable
3cfqB-3rjlA:
undetectable		 3cfqA-3rjlA:
14.40
3cfqB-3rjlA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		5 / 12 GLU A 336
GLU A 303
VAL A 294
ASP A 301
ILE A 450
 None
 1.44A 3jayA-3rjlA:
undetectable		 3jayA-3rjlA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 8 ILE A 376
SER A 387
GLY A 389
PRO A 421
 None
 0.93A 3lslA-3rjlA:
undetectable
3lslD-3rjlA:
undetectable		 3lslA-3rjlA:
20.00
3lslD-3rjlA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 8 PRO A 421
ILE A 376
SER A 387
GLY A 389
 None
 0.91A 3lslA-3rjlA:
undetectable
3lslD-3rjlA:
undetectable		 3lslA-3rjlA:
20.00
3lslD-3rjlA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		3 / 3 VAL A 232
VAL A 101
SER A 225
 None
 0.70A 3n8xB-3rjlA:
2.1		 3n8xB-3rjlA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 425
VAL A 341
ILE A 403
SER A 312
 None
 1.00A 3pglA-3rjlA:
2.6		 3pglA-3rjlA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		5 / 12 GLY A 125
ASP A 365
ILE A 364
GLY A 361
PHE A 398
 None
 1.14A 3ps9A-3rjlA:
2.8		 3ps9A-3rjlA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.44A 3q99A-3rjlA:
undetectable
3q99B-3rjlA:
undetectable		 3q99A-3rjlA:
22.66
3q99B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		5 / 12 THR A 493
SER A 495
TYR A 502
ILE A 254
HIS A 506
 None
 1.23A 3sp6A-3rjlA:
undetectable		 3sp6A-3rjlA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.47A 3uftA-3rjlA:
undetectable
3uftB-3rjlA:
undetectable		 3uftA-3rjlA:
22.66
3uftB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.44A 4ctrA-3rjlA:
undetectable
4ctrB-3rjlA:
undetectable		 4ctrA-3rjlA:
22.66
4ctrB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.46A 4d2zA-3rjlA:
undetectable
4d2zB-3rjlA:
undetectable		 4d2zA-3rjlA:
22.66
4d2zB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 6 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.42A 4imwA-3rjlA:
undetectable
4imwB-3rjlA:
1.0		 4imwA-3rjlA:
22.66
4imwB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.45A 4imwA-3rjlA:
undetectable
4imwB-3rjlA:
1.0		 4imwA-3rjlA:
22.66
4imwB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 6 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.46A 4jshA-3rjlA:
undetectable
4jshB-3rjlA:
undetectable		 4jshA-3rjlA:
22.66
4jshB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.47A 4kchA-3rjlA:
undetectable
4kchB-3rjlA:
undetectable		 4kchA-3rjlA:
22.66
4kchB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.45A 4kciA-3rjlA:
undetectable
4kciB-3rjlA:
undetectable		 4kciA-3rjlA:
22.66
4kciB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.45A 4kckA-3rjlA:
undetectable
4kckB-3rjlA:
undetectable		 4kckA-3rjlA:
22.66
4kckB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.44A 4kclA-3rjlA:
undetectable
4kclB-3rjlA:
1.0		 4kclA-3rjlA:
22.66
4kclB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 8 LEU A 120
PRO A 180
VAL A 194
GLY A 191
 None
 0.95A 4klrB-3rjlA:
2.8		 4klrB-3rjlA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		3 / 3 GLY A 361
PRO A 362
GLN A 319
 None
 0.31A 4oltB-3rjlA:
undetectable		 4oltB-3rjlA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		3 / 3 GLY A 361
PRO A 362
GLN A 319
 None
 0.26A 4qwpB-3rjlA:
undetectable		 4qwpB-3rjlA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.43A 4ugzA-3rjlA:
undetectable
4ugzB-3rjlA:
undetectable		 4ugzA-3rjlA:
22.66
4ugzB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.43A 4uh0A-3rjlA:
undetectable
4uh0B-3rjlA:
undetectable		 4uh0A-3rjlA:
22.66
4uh0B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.42A 4uh0A-3rjlA:
undetectable
4uh0B-3rjlA:
undetectable		 4uh0A-3rjlA:
22.66
4uh0B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.44A 4upnA-3rjlA:
undetectable
4upnB-3rjlA:
1.1		 4upnA-3rjlA:
22.66
4upnB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.44A 5ad5A-3rjlA:
undetectable
5ad5B-3rjlA:
undetectable		 5ad5A-3rjlA:
22.66
5ad5B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 6 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.42A 5ad5A-3rjlA:
undetectable
5ad5B-3rjlA:
undetectable		 5ad5A-3rjlA:
22.66
5ad5B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.45A 5ad6A-3rjlA:
undetectable
5ad6B-3rjlA:
undetectable		 5ad6A-3rjlA:
22.66
5ad6B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 6 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.43A 5ad7A-3rjlA:
undetectable
5ad7B-3rjlA:
undetectable		 5ad7A-3rjlA:
22.66
5ad7B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 6 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.41A 5ad8A-3rjlA:
undetectable
5ad8B-3rjlA:
undetectable		 5ad8A-3rjlA:
22.66
5ad8B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.42A 5adaA-3rjlA:
undetectable
5adaB-3rjlA:
undetectable		 5adaA-3rjlA:
22.66
5adaB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.42A 5fw0A-3rjlA:
undetectable
5fw0B-3rjlA:
undetectable		 5fw0A-3rjlA:
22.66
5fw0B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 6 PHE A 404
VAL A 422
PHE A 314
THR A 345
 None
 0.98A 5t7bA-3rjlA:
3.6		 5t7bA-3rjlA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.42A 5unrA-3rjlA:
undetectable
5unrB-3rjlA:
undetectable		 5unrA-3rjlA:
22.66
5unrB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.47A 5unuA-3rjlA:
undetectable
5unuB-3rjlA:
undetectable		 5unuA-3rjlA:
22.66
5unuB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 6 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.37A 5unvA-3rjlA:
undetectable
5unvB-3rjlA:
undetectable		 5unvA-3rjlA:
22.66
5unvB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.42A 5unwA-3rjlA:
0.9
5unwB-3rjlA:
undetectable		 5unwA-3rjlA:
22.66
5unwB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.43A 5unyA-3rjlA:
undetectable
5unyB-3rjlA:
undetectable		 5unyA-3rjlA:
22.66
5unyB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.42A 5unyA-3rjlA:
undetectable
5unyB-3rjlA:
undetectable		 5unyA-3rjlA:
22.66
5unyB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.41A 5unzA-3rjlA:
undetectable
5unzB-3rjlA:
undetectable		 5unzA-3rjlA:
22.66
5unzB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.41A 5uo0A-3rjlA:
0.9
5uo0B-3rjlA:
undetectable		 5uo0A-3rjlA:
22.66
5uo0B-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.42A 5uo2A-3rjlA:
2.0
5uo2B-3rjlA:
1.0		 5uo2A-3rjlA:
22.59
5uo2B-3rjlA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.42A 5uo3A-3rjlA:
1.6
5uo3B-3rjlA:
undetectable		 5uo3A-3rjlA:
22.59
5uo3B-3rjlA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.46A 5uo6A-3rjlA:
undetectable
5uo6B-3rjlA:
undetectable		 5uo6A-3rjlA:
22.59
5uo6B-3rjlA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.42A 5vuiA-3rjlA:
undetectable
5vuiB-3rjlA:
undetectable		 5vuiA-3rjlA:
22.66
5vuiB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.42A 5vuiA-3rjlA:
undetectable
5vuiB-3rjlA:
undetectable		 5vuiA-3rjlA:
22.66
5vuiB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.42A 5vukA-3rjlA:
undetectable
5vukB-3rjlA:
undetectable		 5vukA-3rjlA:
22.66
5vukB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.42A 5vuoA-3rjlA:
undetectable
5vuoB-3rjlA:
undetectable		 5vuoA-3rjlA:
22.66
5vuoB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.40A 5vuqA-3rjlA:
undetectable
5vuqB-3rjlA:
undetectable		 5vuqA-3rjlA:
22.66
5vuqB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.45A 5vurA-3rjlA:
undetectable
5vurB-3rjlA:
1.1		 5vurA-3rjlA:
22.66
5vurB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.44A 5vuuA-3rjlA:
undetectable
5vuuB-3rjlA:
undetectable		 5vuuA-3rjlA:
22.66
5vuuB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.41A 5vuuA-3rjlA:
undetectable
5vuuB-3rjlA:
undetectable		 5vuuA-3rjlA:
22.66
5vuuB-3rjlA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.42A 5vuvA-3rjlA:
1.0
5vuvB-3rjlA:
2.0		 5vuvA-3rjlA:
22.59
5vuvB-3rjlA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.43A 5vv5A-3rjlA:
undetectable
5vv5B-3rjlA:
undetectable		 5vv5A-3rjlA:
22.59
5vv5B-3rjlA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.45A 6auqA-3rjlA:
undetectable
6auqB-3rjlA:
undetectable		 6auqA-3rjlA:
10.66
6auqB-3rjlA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.43A 6auxA-3rjlA:
undetectable
6auxB-3rjlA:
undetectable		 6auxA-3rjlA:
10.66
6auxB-3rjlA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 ARG A 459
VAL A 295
PHE A 431
GLU A 433
 None
None
None
CD  A 542 (-2.3A)
 1.45A 6av5A-3rjlA:
undetectable
6av5B-3rjlA:
undetectable		 6av5A-3rjlA:
10.87
6av5B-3rjlA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
(Bacillus
licheniformis) 		4 / 7 PHE A 431
GLU A 433
ARG A 459
VAL A 295
 None
CD  A 542 (-2.3A)
None
None
 1.44A 6av5A-3rjlA:
undetectable
6av5B-3rjlA:
undetectable		 6av5A-3rjlA:
10.87
6av5B-3rjlA:
10.87