SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 3rjv PUTATIVE SEL1 REPEAT
PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 GLU A 213
ALA A 180
SER A 171
 None
 0.66A 1errB-3rjvA:
undetectable		 1errB-3rjvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 3rjv PUTATIVE SEL1 REPEAT
PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 TRP A  56
VAL A  45
TRP A  44
 None
 1.38A 1gmkC-3rjvA:
undetectable
1gmkD-3rjvA:
undetectable		 1gmkC-3rjvA:
5.98
1gmkD-3rjvA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3rjv PUTATIVE SEL1 REPEAT
PROTEIN
(Klebsiella
pneumoniae) 		4 / 5 ALA A 131
ALA A  70
ALA A  73
VAL A 110
 None
 0.86A 2nyrB-3rjvA:
undetectable		 2nyrB-3rjvA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 3rjv PUTATIVE SEL1 REPEAT
PROTEIN
(Klebsiella
pneumoniae) 		5 / 12 LEU A 149
GLY A 148
LEU A 146
GLN A 144
PHE A 168
 None
 0.97A 3gwvA-3rjvA:
undetectable		 3gwvA-3rjvA:
18.42