SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rjy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 1k2sA-3rjyA:
undetectable
1k2sB-3rjyA:
undetectable		 1k2sA-3rjyA:
20.18
1k2sB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 1k2sA-3rjyA:
undetectable
1k2sB-3rjyA:
undetectable		 1k2sA-3rjyA:
20.18
1k2sB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 1k2tA-3rjyA:
1.2
1k2tB-3rjyA:
undetectable		 1k2tA-3rjyA:
20.18
1k2tB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 1k2tA-3rjyA:
1.3
1k2tB-3rjyA:
undetectable		 1k2tA-3rjyA:
20.18
1k2tB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 1k2uA-3rjyA:
undetectable
1k2uB-3rjyA:
undetectable		 1k2uA-3rjyA:
20.18
1k2uB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 1k2uA-3rjyA:
undetectable
1k2uB-3rjyA:
undetectable		 1k2uA-3rjyA:
20.18
1k2uB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.23A 1lzxA-3rjyA:
undetectable
1lzxB-3rjyA:
undetectable		 1lzxA-3rjyA:
20.18
1lzxB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 1lzxA-3rjyA:
undetectable
1lzxB-3rjyA:
undetectable		 1lzxA-3rjyA:
20.18
1lzxB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 1lzzA-3rjyA:
undetectable
1lzzB-3rjyA:
undetectable		 1lzzA-3rjyA:
20.18
1lzzB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 1lzzA-3rjyA:
undetectable
1lzzB-3rjyA:
undetectable		 1lzzA-3rjyA:
20.18
1lzzB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 1m00A-3rjyA:
1.4
1m00B-3rjyA:
undetectable		 1m00A-3rjyA:
20.18
1m00B-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 1m00A-3rjyA:
undetectable
1m00B-3rjyA:
undetectable		 1m00A-3rjyA:
20.18
1m00B-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 1mmvA-3rjyA:
undetectable
1mmvB-3rjyA:
undetectable		 1mmvA-3rjyA:
20.18
1mmvB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 1mmvA-3rjyA:
undetectable
1mmvB-3rjyA:
undetectable		 1mmvA-3rjyA:
20.18
1mmvB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.24A 1mmwA-3rjyA:
undetectable
1mmwB-3rjyA:
undetectable		 1mmwA-3rjyA:
20.18
1mmwB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 1mmwA-3rjyA:
undetectable
1mmwB-3rjyA:
undetectable		 1mmwA-3rjyA:
20.18
1mmwB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 ALA A 340
VAL A 302
TRP A 298
 None
 0.89A 1nt6A-3rjyA:
undetectable		 1nt6A-3rjyA:
3.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 ALA A 340
VAL A 302
TRP A 298
 None
 0.89A 1nt6B-3rjyA:
undetectable		 1nt6B-3rjyA:
3.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 1om4A-3rjyA:
undetectable
1om4B-3rjyA:
undetectable		 1om4A-3rjyA:
21.27
1om4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 1om4A-3rjyA:
undetectable
1om4B-3rjyA:
undetectable		 1om4A-3rjyA:
21.27
1om4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 1om5A-3rjyA:
undetectable
1om5B-3rjyA:
undetectable		 1om5A-3rjyA:
21.27
1om5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 1om5A-3rjyA:
undetectable
1om5B-3rjyA:
undetectable		 1om5A-3rjyA:
21.27
1om5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 1p6hA-3rjyA:
undetectable
1p6hB-3rjyA:
undetectable		 1p6hA-3rjyA:
21.27
1p6hB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 1p6hA-3rjyA:
undetectable
1p6hB-3rjyA:
undetectable		 1p6hA-3rjyA:
21.27
1p6hB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 1p6jA-3rjyA:
undetectable
1p6jB-3rjyA:
undetectable		 1p6jA-3rjyA:
21.27
1p6jB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 1p6jA-3rjyA:
undetectable
1p6jB-3rjyA:
undetectable		 1p6jA-3rjyA:
21.27
1p6jB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 1p6kA-3rjyA:
undetectable
1p6kB-3rjyA:
undetectable		 1p6kA-3rjyA:
21.27
1p6kB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 1p6kA-3rjyA:
undetectable
1p6kB-3rjyA:
undetectable		 1p6kA-3rjyA:
21.27
1p6kB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 177
VAL A 201
PRO A 202
 None
 0.98A 1rg1A-3rjyA:
2.3		 1rg1A-3rjyA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 177
VAL A 201
PRO A 202
 None
 0.99A 1rh0A-3rjyA:
2.2		 1rh0A-3rjyA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 1rs6A-3rjyA:
undetectable
1rs6B-3rjyA:
undetectable		 1rs6A-3rjyA:
21.27
1rs6B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 1rs6A-3rjyA:
undetectable
1rs6B-3rjyA:
undetectable		 1rs6A-3rjyA:
21.27
1rs6B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.24A 1rs7A-3rjyA:
undetectable
1rs7B-3rjyA:
undetectable		 1rs7A-3rjyA:
21.27
1rs7B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 1rs7A-3rjyA:
undetectable
1rs7B-3rjyA:
undetectable		 1rs7A-3rjyA:
21.27
1rs7B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		5 / 11 ILE A 145
VAL A 149
ALA A 150
PHE A 153
LEU A 160
 None
 0.73A 1uduA-3rjyA:
undetectable		 1uduA-3rjyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		5 / 12 ILE A 145
VAL A 149
ALA A 150
PHE A 153
LEU A 160
 None
 0.73A 1uduB-3rjyA:
undetectable		 1uduB-3rjyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 5 VAL A 277
ASN A 275
VAL A 223
ILE A 221
 None
 1.07A 1z2bC-3rjyA:
undetectable		 1z2bC-3rjyA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 1zzqA-3rjyA:
undetectable
1zzqB-3rjyA:
undetectable		 1zzqA-3rjyA:
20.18
1zzqB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 1zzqA-3rjyA:
undetectable
1zzqB-3rjyA:
undetectable		 1zzqA-3rjyA:
20.18
1zzqB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 1zzrA-3rjyA:
undetectable
1zzrB-3rjyA:
undetectable		 1zzrA-3rjyA:
20.18
1zzrB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 1zzuA-3rjyA:
1.5
1zzuB-3rjyA:
undetectable		 1zzuA-3rjyA:
20.18
1zzuB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 1zzuA-3rjyA:
1.5
1zzuB-3rjyA:
undetectable		 1zzuA-3rjyA:
20.18
1zzuB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.24A 2g6hA-3rjyA:
undetectable
2g6hB-3rjyA:
undetectable		 2g6hA-3rjyA:
20.18
2g6hB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 2g6hA-3rjyA:
undetectable
2g6hB-3rjyA:
undetectable		 2g6hA-3rjyA:
20.18
2g6hB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.23A 2g6kA-3rjyA:
undetectable
2g6kB-3rjyA:
undetectable		 2g6kA-3rjyA:
20.18
2g6kB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 2g6kA-3rjyA:
undetectable
2g6kB-3rjyA:
undetectable		 2g6kA-3rjyA:
20.18
2g6kB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 2g6mA-3rjyA:
undetectable
2g6mB-3rjyA:
undetectable		 2g6mA-3rjyA:
20.18
2g6mB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 2g6mA-3rjyA:
undetectable
2g6mB-3rjyA:
undetectable		 2g6mA-3rjyA:
20.18
2g6mB-3rjyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 2hx3A-3rjyA:
undetectable
2hx3B-3rjyA:
undetectable		 2hx3A-3rjyA:
21.27
2hx3B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 2hx3A-3rjyA:
undetectable
2hx3B-3rjyA:
undetectable		 2hx3A-3rjyA:
21.27
2hx3B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 2hx4A-3rjyA:
undetectable
2hx4B-3rjyA:
undetectable		 2hx4A-3rjyA:
21.27
2hx4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 2hx4A-3rjyA:
undetectable
2hx4B-3rjyA:
undetectable		 2hx4A-3rjyA:
21.27
2hx4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		6 / 12 ASN A 166
GLU A 167
HIS A 226
TYR A 228
GLU A 283
TRP A 316
 None
GLC  A 402 (-2.9A)
None
GLC  A 402 ( 3.4A)
GLC  A 403 (-2.5A)
GLC  A 403 (-3.4A)
 0.75A 2v3dA-3rjyA:
18.3		 2v3dA-3rjyA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		5 / 11 ASN A 166
GLU A 167
TYR A 228
GLU A 283
TRP A 316
 None
GLC  A 402 (-2.9A)
GLC  A 402 ( 3.4A)
GLC  A 403 (-2.5A)
GLC  A 403 (-3.4A)
 0.85A 2v3dB-3rjyA:
12.7		 2v3dB-3rjyA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 VAL A 249
TRP A 298
TRP A 251
 None
 1.36A 2xdcA-3rjyA:
undetectable
2xdcB-3rjyA:
undetectable		 2xdcA-3rjyA:
2.85
2xdcB-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 251
VAL A 249
TRP A 298
 None
 1.36A 2xdcA-3rjyA:
undetectable
2xdcB-3rjyA:
undetectable		 2xdcA-3rjyA:
2.85
2xdcB-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 VAL A 249
TRP A 298
TRP A 251
 None
 1.04A 2xdcC-3rjyA:
undetectable
2xdcD-3rjyA:
undetectable		 2xdcC-3rjyA:
2.85
2xdcD-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 146
VAL A 141
TRP A  87
 None
 1.15A 2xdcC-3rjyA:
undetectable
2xdcD-3rjyA:
undetectable		 2xdcC-3rjyA:
2.85
2xdcD-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 251
VAL A 249
TRP A 298
 None
 1.32A 2xdcC-3rjyA:
undetectable
2xdcD-3rjyA:
undetectable		 2xdcC-3rjyA:
2.85
2xdcD-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 146
VAL A 141
TRP A  87
 None
 1.15A 2xdcE-3rjyA:
undetectable
2xdcF-3rjyA:
undetectable		 2xdcE-3rjyA:
2.85
2xdcF-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 251
VAL A 249
TRP A 298
 None
 1.31A 2xdcE-3rjyA:
undetectable
2xdcF-3rjyA:
undetectable		 2xdcE-3rjyA:
2.85
2xdcF-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 VAL A 249
TRP A 298
TRP A 251
 None
 1.35A 2y5mA-3rjyA:
undetectable
2y5mB-3rjyA:
undetectable		 2y5mA-3rjyA:
2.85
2y5mB-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 146
VAL A 141
TRP A  87
 None
 1.11A 2y5mE-3rjyA:
undetectable
2y5mF-3rjyA:
undetectable		 2y5mE-3rjyA:
2.85
2y5mF-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 251
VAL A 249
TRP A 298
 None
 1.31A 2y5mE-3rjyA:
undetectable
2y5mF-3rjyA:
undetectable		 2y5mE-3rjyA:
2.85
2y5mF-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 VAL A 249
TRP A 298
TRP A 251
 None
 1.35A 2y6nA-3rjyA:
undetectable
2y6nB-3rjyA:
undetectable		 2y6nA-3rjyA:
2.85
2y6nB-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 251
VAL A 249
TRP A 298
 None
 1.34A 2y6nA-3rjyA:
undetectable
2y6nB-3rjyA:
undetectable		 2y6nA-3rjyA:
2.85
2y6nB-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 146
VAL A 141
TRP A  87
 None
 1.12A 2y6nC-3rjyA:
undetectable
2y6nD-3rjyA:
undetectable		 2y6nC-3rjyA:
2.85
2y6nD-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 251
VAL A 249
TRP A 298
 None
 1.29A 2y6nC-3rjyA:
undetectable
2y6nD-3rjyA:
undetectable		 2y6nC-3rjyA:
2.85
2y6nD-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 146
VAL A 141
TRP A  87
 None
 1.13A 2y6nE-3rjyA:
undetectable
2y6nF-3rjyA:
undetectable		 2y6nE-3rjyA:
2.85
2y6nF-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 TRP A 251
VAL A 249
TRP A 298
 None
 1.30A 2y6nE-3rjyA:
undetectable
2y6nF-3rjyA:
undetectable		 2y6nE-3rjyA:
2.85
2y6nF-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 3b3mA-3rjyA:
1.5
3b3mB-3rjyA:
undetectable		 3b3mA-3rjyA:
21.27
3b3mB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3b3mA-3rjyA:
1.5
3b3mB-3rjyA:
undetectable		 3b3mA-3rjyA:
21.27
3b3mB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 3b3nA-3rjyA:
0.0
3b3nB-3rjyA:
0.0		 3b3nA-3rjyA:
21.27
3b3nB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3b3nA-3rjyA:
0.0
3b3nB-3rjyA:
0.0		 3b3nA-3rjyA:
21.27
3b3nB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 3b3oA-3rjyA:
undetectable
3b3oB-3rjyA:
undetectable		 3b3oA-3rjyA:
21.27
3b3oB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3b3oA-3rjyA:
undetectable
3b3oB-3rjyA:
undetectable		 3b3oA-3rjyA:
21.27
3b3oB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3b3pA-3rjyA:
undetectable
3b3pB-3rjyA:
undetectable		 3b3pA-3rjyA:
21.27
3b3pB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 3b3pA-3rjyA:
undetectable
3b3pB-3rjyA:
undetectable		 3b3pA-3rjyA:
21.27
3b3pB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3dqrA-3rjyA:
undetectable
3dqrB-3rjyA:
undetectable		 3dqrA-3rjyA:
20.09
3dqrB-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3dqrA-3rjyA:
undetectable
3dqrB-3rjyA:
undetectable		 3dqrA-3rjyA:
20.09
3dqrB-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 3fc5A-3rjyA:
undetectable
3fc5B-3rjyA:
undetectable		 3fc5A-3rjyA:
21.27
3fc5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3fc5A-3rjyA:
undetectable
3fc5B-3rjyA:
undetectable		 3fc5A-3rjyA:
21.27
3fc5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.24A 3hsnA-3rjyA:
undetectable
3hsnB-3rjyA:
undetectable		 3hsnA-3rjyA:
21.27
3hsnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.24A 3hsnA-3rjyA:
undetectable
3hsnB-3rjyA:
undetectable		 3hsnA-3rjyA:
21.27
3hsnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3hsoA-3rjyA:
undetectable
3hsoB-3rjyA:
undetectable		 3hsoA-3rjyA:
21.27
3hsoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.22A 3hsoA-3rjyA:
undetectable
3hsoB-3rjyA:
undetectable		 3hsoA-3rjyA:
21.27
3hsoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3hspA-3rjyA:
undetectable
3hspB-3rjyA:
undetectable		 3hspA-3rjyA:
21.27
3hspB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3hspA-3rjyA:
undetectable
3hspB-3rjyA:
undetectable		 3hspA-3rjyA:
21.27
3hspB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3jt3A-3rjyA:
undetectable
3jt3B-3rjyA:
1.1		 3jt3A-3rjyA:
21.27
3jt3B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 3jt3A-3rjyA:
undetectable
3jt3B-3rjyA:
1.1		 3jt3A-3rjyA:
21.27
3jt3B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 3jt4A-3rjyA:
undetectable
3jt4B-3rjyA:
1.4		 3jt4A-3rjyA:
21.27
3jt4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3jt4A-3rjyA:
undetectable
3jt4B-3rjyA:
1.4		 3jt4A-3rjyA:
21.27
3jt4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 3jt5A-3rjyA:
undetectable
3jt5B-3rjyA:
undetectable		 3jt5A-3rjyA:
21.27
3jt5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3jt5A-3rjyA:
undetectable
3jt5B-3rjyA:
undetectable		 3jt5A-3rjyA:
21.27
3jt5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 3jt6A-3rjyA:
undetectable
3jt6B-3rjyA:
undetectable		 3jt6A-3rjyA:
21.27
3jt6B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3jt6A-3rjyA:
undetectable
3jt6B-3rjyA:
undetectable		 3jt6A-3rjyA:
21.27
3jt6B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3jt7A-3rjyA:
undetectable
3jt7B-3rjyA:
undetectable		 3jt7A-3rjyA:
21.27
3jt7B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3jt7A-3rjyA:
undetectable
3jt7B-3rjyA:
undetectable		 3jt7A-3rjyA:
21.27
3jt7B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3jt8A-3rjyA:
undetectable
3jt8B-3rjyA:
1.4		 3jt8A-3rjyA:
21.27
3jt8B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3jt8A-3rjyA:
undetectable
3jt8B-3rjyA:
1.4		 3jt8A-3rjyA:
21.27
3jt8B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 3jt9A-3rjyA:
undetectable
3jt9B-3rjyA:
1.4		 3jt9A-3rjyA:
21.27
3jt9B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3jt9A-3rjyA:
undetectable
3jt9B-3rjyA:
1.4		 3jt9A-3rjyA:
21.27
3jt9B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 3jtaA-3rjyA:
undetectable
3jtaB-3rjyA:
undetectable		 3jtaA-3rjyA:
21.27
3jtaB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3jtaA-3rjyA:
undetectable
3jtaB-3rjyA:
undetectable		 3jtaA-3rjyA:
21.27
3jtaB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3jwsA-3rjyA:
0.0
3jwsB-3rjyA:
undetectable		 3jwsA-3rjyA:
21.27
3jwsB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3jwsA-3rjyA:
0.0
3jwsB-3rjyA:
undetectable		 3jwsA-3rjyA:
21.27
3jwsB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3jwtA-3rjyA:
undetectable
3jwtB-3rjyA:
1.3		 3jwtA-3rjyA:
21.27
3jwtB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3jwtA-3rjyA:
undetectable
3jwtB-3rjyA:
1.3		 3jwtA-3rjyA:
21.27
3jwtB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3jwuA-3rjyA:
undetectable
3jwuB-3rjyA:
1.3		 3jwuA-3rjyA:
21.27
3jwuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 3jwuA-3rjyA:
undetectable
3jwuB-3rjyA:
1.3		 3jwuA-3rjyA:
21.27
3jwuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3jwvA-3rjyA:
undetectable
3jwvB-3rjyA:
1.3		 3jwvA-3rjyA:
21.27
3jwvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 3jwvA-3rjyA:
undetectable
3jwvB-3rjyA:
1.3		 3jwvA-3rjyA:
21.27
3jwvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3jx0A-3rjyA:
1.1
3jx0B-3rjyA:
undetectable		 3jx0A-3rjyA:
21.27
3jx0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 3jx0A-3rjyA:
1.0
3jx0B-3rjyA:
undetectable		 3jx0A-3rjyA:
21.27
3jx0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3jx1A-3rjyA:
1.4
3jx1B-3rjyA:
undetectable		 3jx1A-3rjyA:
21.27
3jx1B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3jx2A-3rjyA:
undetectable
3jx2B-3rjyA:
undetectable		 3jx2A-3rjyA:
20.09
3jx2B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3jx2A-3rjyA:
undetectable
3jx2B-3rjyA:
undetectable		 3jx2A-3rjyA:
20.09
3jx2B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3jx3A-3rjyA:
1.4
3jx3B-3rjyA:
undetectable		 3jx3A-3rjyA:
20.09
3jx3B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3jx3A-3rjyA:
1.4
3jx3B-3rjyA:
undetectable		 3jx3A-3rjyA:
20.09
3jx3B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 3jx4A-3rjyA:
0.2
3jx4B-3rjyA:
1.4		 3jx4A-3rjyA:
20.09
3jx4B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3jx5A-3rjyA:
undetectable
3jx5B-3rjyA:
1.4		 3jx5A-3rjyA:
20.09
3jx5B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 PHE A 309
GLY A 310
PHE A 311
PHE A 225
 None
 1.13A 3ko0D-3rjyA:
undetectable
3ko0E-3rjyA:
undetectable		 3ko0D-3rjyA:
15.94
3ko0E-3rjyA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 3n2rA-3rjyA:
undetectable
3n2rB-3rjyA:
undetectable		 3n2rA-3rjyA:
21.27
3n2rB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3n2rA-3rjyA:
undetectable
3n2rB-3rjyA:
undetectable		 3n2rA-3rjyA:
21.27
3n2rB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 3n5vA-3rjyA:
undetectable
3n5vB-3rjyA:
undetectable		 3n5vA-3rjyA:
21.27
3n5vB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 3n5yA-3rjyA:
undetectable
3n5yB-3rjyA:
undetectable		 3n5yA-3rjyA:
21.27
3n5yB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3n5yA-3rjyA:
undetectable
3n5yB-3rjyA:
undetectable		 3n5yA-3rjyA:
21.27
3n5yB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3n5zA-3rjyA:
undetectable
3n5zB-3rjyA:
1.4		 3n5zA-3rjyA:
21.27
3n5zB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 3n5zA-3rjyA:
undetectable
3n5zB-3rjyA:
1.4		 3n5zA-3rjyA:
21.27
3n5zB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3n61A-3rjyA:
1.5
3n61B-3rjyA:
1.1		 3n61A-3rjyA:
20.09
3n61B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3n61A-3rjyA:
1.5
3n61B-3rjyA:
1.1		 3n61A-3rjyA:
20.09
3n61B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3n65A-3rjyA:
undetectable
3n65B-3rjyA:
undetectable		 3n65A-3rjyA:
21.27
3n65B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 3nljA-3rjyA:
1.6
3nljB-3rjyA:
undetectable		 3nljA-3rjyA:
20.31
3nljB-3rjyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 3nlkA-3rjyA:
undetectable
3nlkB-3rjyA:
undetectable		 3nlkA-3rjyA:
21.27
3nlkB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3nlkA-3rjyA:
undetectable
3nlkB-3rjyA:
undetectable		 3nlkA-3rjyA:
21.27
3nlkB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3nlmA-3rjyA:
undetectable
3nlmB-3rjyA:
0.0		 3nlmA-3rjyA:
21.27
3nlmB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3nlmA-3rjyA:
undetectable
3nlmB-3rjyA:
0.0		 3nlmA-3rjyA:
21.27
3nlmB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3nlnA-3rjyA:
undetectable
3nlnB-3rjyA:
undetectable		 3nlnA-3rjyA:
21.27
3nlnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 3nlnA-3rjyA:
undetectable
3nlnB-3rjyA:
undetectable		 3nlnA-3rjyA:
21.27
3nlnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 3nloA-3rjyA:
undetectable
3nloB-3rjyA:
0.8		 3nloA-3rjyA:
21.27
3nloB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 3nloA-3rjyA:
undetectable
3nloB-3rjyA:
0.8		 3nloA-3rjyA:
21.27
3nloB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3nlvA-3rjyA:
1.5
3nlvB-3rjyA:
1.2		 3nlvA-3rjyA:
21.27
3nlvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3nlvA-3rjyA:
1.5
3nlvB-3rjyA:
1.2		 3nlvA-3rjyA:
21.27
3nlvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3nlwA-3rjyA:
undetectable
3nlwB-3rjyA:
1.4		 3nlwA-3rjyA:
21.27
3nlwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3nlwA-3rjyA:
undetectable
3nlwB-3rjyA:
1.4		 3nlwA-3rjyA:
21.27
3nlwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3nlxA-3rjyA:
undetectable
3nlxB-3rjyA:
undetectable		 3nlxA-3rjyA:
21.27
3nlxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3nlxA-3rjyA:
undetectable
3nlxB-3rjyA:
undetectable		 3nlxA-3rjyA:
21.27
3nlxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.32A 3nlyA-3rjyA:
1.3
3nlyB-3rjyA:
undetectable		 3nlyA-3rjyA:
21.27
3nlyB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3nlyA-3rjyA:
1.3
3nlyB-3rjyA:
undetectable		 3nlyA-3rjyA:
21.27
3nlyB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3nlzA-3rjyA:
undetectable
3nlzB-3rjyA:
undetectable		 3nlzA-3rjyA:
21.27
3nlzB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3nlzA-3rjyA:
undetectable
3nlzB-3rjyA:
undetectable		 3nlzA-3rjyA:
21.27
3nlzB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3nm0A-3rjyA:
undetectable
3nm0B-3rjyA:
undetectable		 3nm0A-3rjyA:
21.27
3nm0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3nm0A-3rjyA:
undetectable
3nm0B-3rjyA:
undetectable		 3nm0A-3rjyA:
21.27
3nm0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3nnyA-3rjyA:
1.1
3nnyB-3rjyA:
undetectable		 3nnyA-3rjyA:
21.27
3nnyB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.24A 3nnzA-3rjyA:
undetectable
3nnzB-3rjyA:
undetectable		 3nnzA-3rjyA:
21.27
3nnzB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3nnzA-3rjyA:
undetectable
3nnzB-3rjyA:
undetectable		 3nnzA-3rjyA:
21.27
3nnzB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3pneA-3rjyA:
1.4
3pneB-3rjyA:
undetectable		 3pneA-3rjyA:
21.27
3pneB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3pneA-3rjyA:
1.2
3pneB-3rjyA:
undetectable		 3pneA-3rjyA:
21.27
3pneB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3pnfA-3rjyA:
undetectable
3pnfB-3rjyA:
undetectable		 3pnfA-3rjyA:
21.27
3pnfB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3pnfA-3rjyA:
undetectable
3pnfB-3rjyA:
undetectable		 3pnfA-3rjyA:
21.27
3pnfB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3pngA-3rjyA:
undetectable
3pngB-3rjyA:
undetectable		 3pngA-3rjyA:
21.27
3pngB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3pngA-3rjyA:
undetectable
3pngB-3rjyA:
undetectable		 3pngA-3rjyA:
21.27
3pngB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 3q99A-3rjyA:
undetectable
3q99B-3rjyA:
undetectable		 3q99A-3rjyA:
21.27
3q99B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3q99A-3rjyA:
undetectable
3q99B-3rjyA:
undetectable		 3q99A-3rjyA:
21.27
3q99B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 3q9aA-3rjyA:
undetectable
3q9aB-3rjyA:
undetectable		 3q9aA-3rjyA:
21.27
3q9aB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		5 / 11 PRO A  84
ILE A 123
VAL A 107
VAL A 111
ILE A  65
 None
 1.29A 3rf4A-3rjyA:
undetectable
3rf4C-3rjyA:
undetectable		 3rf4A-3rjyA:
14.95
3rf4C-3rjyA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		5 / 11 ILE A  65
PRO A  84
ILE A 123
VAL A 107
VAL A 111
 None
 1.32A 3rf4A-3rjyA:
undetectable
3rf4B-3rjyA:
undetectable		 3rf4A-3rjyA:
14.95
3rf4B-3rjyA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		5 / 11 ILE A  65
PRO A  84
ILE A 123
VAL A 107
VAL A 111
 None
 1.29A 3rf4B-3rjyA:
undetectable
3rf4C-3rjyA:
undetectable		 3rf4B-3rjyA:
14.95
3rf4C-3rjyA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3rqjA-3rjyA:
undetectable
3rqjB-3rjyA:
undetectable		 3rqjA-3rjyA:
21.27
3rqjB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3rqjA-3rjyA:
undetectable
3rqjB-3rjyA:
undetectable		 3rqjA-3rjyA:
21.27
3rqjB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 3rqkA-3rjyA:
1.4
3rqkB-3rjyA:
undetectable		 3rqkA-3rjyA:
21.27
3rqkB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3rqlA-3rjyA:
1.5
3rqlB-3rjyA:
undetectable		 3rqlA-3rjyA:
21.27
3rqlB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3rqlA-3rjyA:
1.5
3rqlB-3rjyA:
undetectable		 3rqlA-3rjyA:
21.27
3rqlB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3rqmA-3rjyA:
undetectable
3rqmB-3rjyA:
undetectable		 3rqmA-3rjyA:
21.27
3rqmB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3rqmA-3rjyA:
undetectable
3rqmB-3rjyA:
undetectable		 3rqmA-3rjyA:
21.27
3rqmB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3rqnA-3rjyA:
0.9
3rqnB-3rjyA:
undetectable		 3rqnA-3rjyA:
21.27
3rqnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 3rqnA-3rjyA:
0.9
3rqnB-3rjyA:
undetectable		 3rqnA-3rjyA:
21.27
3rqnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3svpA-3rjyA:
1.3
3svpB-3rjyA:
1.4		 3svpA-3rjyA:
21.27
3svpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3svpA-3rjyA:
1.4
3svpB-3rjyA:
1.4		 3svpA-3rjyA:
21.27
3svpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3svqA-3rjyA:
1.4
3svqB-3rjyA:
undetectable		 3svqA-3rjyA:
21.27
3svqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 3svqA-3rjyA:
1.4
3svqB-3rjyA:
undetectable		 3svqA-3rjyA:
21.27
3svqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3tylA-3rjyA:
undetectable
3tylB-3rjyA:
undetectable		 3tylA-3rjyA:
21.27
3tylB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3tylA-3rjyA:
undetectable
3tylB-3rjyA:
undetectable		 3tylA-3rjyA:
21.27
3tylB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3tymA-3rjyA:
undetectable
3tymB-3rjyA:
undetectable		 3tymA-3rjyA:
21.27
3tymB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3tymA-3rjyA:
undetectable
3tymB-3rjyA:
undetectable		 3tymA-3rjyA:
21.27
3tymB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3tynA-3rjyA:
undetectable
3tynB-3rjyA:
undetectable		 3tynA-3rjyA:
21.27
3tynB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3tynA-3rjyA:
undetectable
3tynB-3rjyA:
undetectable		 3tynA-3rjyA:
21.27
3tynB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3tyoA-3rjyA:
0.8
3tyoB-3rjyA:
undetectable		 3tyoA-3rjyA:
21.27
3tyoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3tyoA-3rjyA:
0.8
3tyoB-3rjyA:
undetectable		 3tyoA-3rjyA:
21.27
3tyoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3ufoA-3rjyA:
undetectable
3ufoB-3rjyA:
undetectable		 3ufoA-3rjyA:
21.27
3ufoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 3ufoA-3rjyA:
undetectable
3ufoB-3rjyA:
undetectable		 3ufoA-3rjyA:
21.27
3ufoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 3ufpA-3rjyA:
undetectable
3ufpB-3rjyA:
undetectable		 3ufpA-3rjyA:
21.27
3ufpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 3ufpA-3rjyA:
undetectable
3ufpB-3rjyA:
undetectable		 3ufpA-3rjyA:
21.27
3ufpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3ufqA-3rjyA:
undetectable
3ufqB-3rjyA:
undetectable		 3ufqA-3rjyA:
21.27
3ufqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3ufqA-3rjyA:
undetectable
3ufqB-3rjyA:
undetectable		 3ufqA-3rjyA:
21.27
3ufqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3ufrA-3rjyA:
undetectable
3ufrB-3rjyA:
undetectable		 3ufrA-3rjyA:
21.27
3ufrB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3ufsA-3rjyA:
undetectable
3ufsB-3rjyA:
undetectable		 3ufsA-3rjyA:
21.27
3ufsB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 3ufsA-3rjyA:
undetectable
3ufsB-3rjyA:
undetectable		 3ufsA-3rjyA:
21.27
3ufsB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 3uftA-3rjyA:
1.2
3uftB-3rjyA:
undetectable		 3uftA-3rjyA:
21.27
3uftB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3uftA-3rjyA:
1.2
3uftB-3rjyA:
undetectable		 3uftA-3rjyA:
21.27
3uftB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 3ufuA-3rjyA:
undetectable
3ufuB-3rjyA:
undetectable		 3ufuA-3rjyA:
21.27
3ufuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3ufuA-3rjyA:
undetectable
3ufuB-3rjyA:
undetectable		 3ufuA-3rjyA:
21.27
3ufuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 3ufvA-3rjyA:
1.3
3ufvB-3rjyA:
undetectable		 3ufvA-3rjyA:
21.27
3ufvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 3ufvA-3rjyA:
1.3
3ufvB-3rjyA:
undetectable		 3ufvA-3rjyA:
21.27
3ufvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 3ufwA-3rjyA:
undetectable
3ufwB-3rjyA:
1.4		 3ufwA-3rjyA:
21.27
3ufwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 3ufwA-3rjyA:
undetectable
3ufwB-3rjyA:
1.4		 3ufwA-3rjyA:
21.27
3ufwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 TRP A 328
THR A 329
TYR A  69
TYR A 325
 None
 1.46A 3wipA-3rjyA:
undetectable
3wipE-3rjyA:
undetectable		 3wipA-3rjyA:
20.90
3wipE-3rjyA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 VAL A 249
TRP A 298
TRP A 251
 None
 1.00A 3zq8A-3rjyA:
undetectable
3zq8B-3rjyA:
undetectable		 3zq8A-3rjyA:
2.85
3zq8B-3rjyA:
2.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4c39A-3rjyA:
1.4
4c39B-3rjyA:
undetectable		 4c39A-3rjyA:
21.27
4c39B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4c39A-3rjyA:
1.1
4c39B-3rjyA:
undetectable		 4c39A-3rjyA:
21.27
4c39B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4camA-3rjyA:
undetectable
4camB-3rjyA:
1.3		 4camA-3rjyA:
21.27
4camB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4camA-3rjyA:
undetectable
4camB-3rjyA:
1.3		 4camA-3rjyA:
21.27
4camB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4canA-3rjyA:
undetectable
4canB-3rjyA:
1.2		 4canA-3rjyA:
21.27
4canB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4canA-3rjyA:
1.4
4canB-3rjyA:
1.2		 4canA-3rjyA:
21.27
4canB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4caoA-3rjyA:
undetectable
4caoB-3rjyA:
1.4		 4caoA-3rjyA:
21.27
4caoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 4caoA-3rjyA:
undetectable
4caoB-3rjyA:
1.4		 4caoA-3rjyA:
21.27
4caoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4capA-3rjyA:
1.2
4capB-3rjyA:
undetectable		 4capA-3rjyA:
21.27
4capB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4capA-3rjyA:
1.3
4capB-3rjyA:
undetectable		 4capA-3rjyA:
21.27
4capB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4caqA-3rjyA:
undetectable
4caqB-3rjyA:
undetectable		 4caqA-3rjyA:
21.27
4caqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4caqA-3rjyA:
undetectable
4caqB-3rjyA:
undetectable		 4caqA-3rjyA:
21.27
4caqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 4cdtA-3rjyA:
undetectable
4cdtB-3rjyA:
1.3		 4cdtA-3rjyA:
21.27
4cdtB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4cdtA-3rjyA:
undetectable
4cdtB-3rjyA:
1.3		 4cdtA-3rjyA:
21.27
4cdtB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4ctpA-3rjyA:
undetectable
4ctpB-3rjyA:
undetectable		 4ctpA-3rjyA:
21.27
4ctpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4ctpA-3rjyA:
undetectable
4ctpB-3rjyA:
undetectable		 4ctpA-3rjyA:
21.27
4ctpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4ctqA-3rjyA:
0.3
4ctqB-3rjyA:
undetectable		 4ctqA-3rjyA:
21.27
4ctqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4ctqA-3rjyA:
undetectable
4ctqB-3rjyA:
undetectable		 4ctqA-3rjyA:
21.27
4ctqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.32A 4ctrA-3rjyA:
1.4
4ctrB-3rjyA:
undetectable		 4ctrA-3rjyA:
21.27
4ctrB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 4ctrA-3rjyA:
1.4
4ctrB-3rjyA:
undetectable		 4ctrA-3rjyA:
21.27
4ctrB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.33A 4cttA-3rjyA:
undetectable
4cttB-3rjyA:
undetectable		 4cttA-3rjyA:
21.27
4cttB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.33A 4cttA-3rjyA:
undetectable
4cttB-3rjyA:
undetectable		 4cttA-3rjyA:
21.27
4cttB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4ctuA-3rjyA:
undetectable
4ctuB-3rjyA:
undetectable		 4ctuA-3rjyA:
21.27
4ctuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4ctuA-3rjyA:
undetectable
4ctuB-3rjyA:
undetectable		 4ctuA-3rjyA:
21.27
4ctuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4ctvA-3rjyA:
1.2
4ctvB-3rjyA:
1.2		 4ctvA-3rjyA:
21.27
4ctvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4ctvA-3rjyA:
1.2
4ctvB-3rjyA:
1.2		 4ctvA-3rjyA:
21.27
4ctvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4ctwA-3rjyA:
undetectable
4ctwB-3rjyA:
undetectable		 4ctwA-3rjyA:
21.27
4ctwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4ctwA-3rjyA:
undetectable
4ctwB-3rjyA:
undetectable		 4ctwA-3rjyA:
21.27
4ctwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4ctxA-3rjyA:
1.3
4ctxB-3rjyA:
undetectable		 4ctxA-3rjyA:
21.27
4ctxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4ctxA-3rjyA:
1.1
4ctxB-3rjyA:
undetectable		 4ctxA-3rjyA:
21.27
4ctxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4cx3A-3rjyA:
1.3
4cx3B-3rjyA:
undetectable		 4cx3A-3rjyA:
20.09
4cx3B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4cx3A-3rjyA:
1.3
4cx3B-3rjyA:
undetectable		 4cx3A-3rjyA:
20.09
4cx3B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4cx4A-3rjyA:
undetectable
4cx4B-3rjyA:
undetectable		 4cx4A-3rjyA:
20.09
4cx4B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 4cx4A-3rjyA:
undetectable
4cx4B-3rjyA:
undetectable		 4cx4A-3rjyA:
20.09
4cx4B-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4cx5A-3rjyA:
undetectable
4cx5B-3rjyA:
undetectable		 4cx5A-3rjyA:
21.27
4cx5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4cx5A-3rjyA:
undetectable
4cx5B-3rjyA:
undetectable		 4cx5A-3rjyA:
21.27
4cx5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4cx6A-3rjyA:
undetectable
4cx6B-3rjyA:
undetectable		 4cx6A-3rjyA:
21.27
4cx6B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4cx6A-3rjyA:
undetectable
4cx6B-3rjyA:
undetectable		 4cx6A-3rjyA:
21.27
4cx6B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.23A 4d1nA-3rjyA:
undetectable
4d1nB-3rjyA:
undetectable		 4d1nA-3rjyA:
20.78
4d1nB-3rjyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4d1nA-3rjyA:
undetectable
4d1nB-3rjyA:
undetectable		 4d1nA-3rjyA:
20.78
4d1nB-3rjyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4d1nC-3rjyA:
undetectable
4d1nD-3rjyA:
undetectable		 4d1nC-3rjyA:
20.78
4d1nD-3rjyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 4d1nC-3rjyA:
undetectable
4d1nD-3rjyA:
undetectable		 4d1nC-3rjyA:
20.78
4d1nD-3rjyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4d2yA-3rjyA:
undetectable
4d2yB-3rjyA:
undetectable		 4d2yA-3rjyA:
21.27
4d2yB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4d2yA-3rjyA:
undetectable
4d2yB-3rjyA:
undetectable		 4d2yA-3rjyA:
21.27
4d2yB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4d2zA-3rjyA:
1.4
4d2zB-3rjyA:
undetectable		 4d2zA-3rjyA:
21.27
4d2zB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4d2zA-3rjyA:
1.4
4d2zB-3rjyA:
undetectable		 4d2zA-3rjyA:
21.27
4d2zB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4d30A-3rjyA:
undetectable
4d30B-3rjyA:
undetectable		 4d30A-3rjyA:
21.27
4d30B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4d30A-3rjyA:
undetectable
4d30B-3rjyA:
undetectable		 4d30A-3rjyA:
21.27
4d30B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 4d31A-3rjyA:
undetectable
4d31B-3rjyA:
undetectable		 4d31A-3rjyA:
21.27
4d31B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4d31A-3rjyA:
undetectable
4d31B-3rjyA:
undetectable		 4d31A-3rjyA:
21.27
4d31B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 4d32A-3rjyA:
undetectable
4d32B-3rjyA:
undetectable		 4d32A-3rjyA:
21.27
4d32B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.32A 4d32A-3rjyA:
undetectable
4d32B-3rjyA:
undetectable		 4d32A-3rjyA:
21.27
4d32B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4d3bA-3rjyA:
undetectable
4d3bB-3rjyA:
undetectable		 4d3bA-3rjyA:
21.27
4d3bB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4d3bA-3rjyA:
undetectable
4d3bB-3rjyA:
undetectable		 4d3bA-3rjyA:
21.27
4d3bB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4d7oA-3rjyA:
undetectable
4d7oB-3rjyA:
undetectable		 4d7oA-3rjyA:
21.27
4d7oB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4d7oA-3rjyA:
undetectable
4d7oB-3rjyA:
undetectable		 4d7oA-3rjyA:
21.27
4d7oB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4euxA-3rjyA:
undetectable
4euxB-3rjyA:
1.5		 4euxA-3rjyA:
21.27
4euxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4euxA-3rjyA:
undetectable
4euxB-3rjyA:
1.5		 4euxA-3rjyA:
21.27
4euxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4fvwA-3rjyA:
undetectable
4fvwB-3rjyA:
1.3		 4fvwA-3rjyA:
21.27
4fvwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4fvwA-3rjyA:
undetectable
4fvwB-3rjyA:
1.3		 4fvwA-3rjyA:
21.27
4fvwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4fvxA-3rjyA:
undetectable
4fvxB-3rjyA:
1.3		 4fvxA-3rjyA:
21.27
4fvxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 4fvxA-3rjyA:
undetectable
4fvxB-3rjyA:
1.2		 4fvxA-3rjyA:
21.27
4fvxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 4fvyA-3rjyA:
undetectable
4fvyB-3rjyA:
undetectable		 4fvyA-3rjyA:
21.27
4fvyB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4fvyA-3rjyA:
undetectable
4fvyB-3rjyA:
undetectable		 4fvyA-3rjyA:
21.27
4fvyB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4fvzA-3rjyA:
undetectable
4fvzB-3rjyA:
undetectable		 4fvzA-3rjyA:
21.27
4fvzB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4fw0A-3rjyA:
undetectable
4fw0B-3rjyA:
undetectable		 4fw0A-3rjyA:
21.27
4fw0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4fw0A-3rjyA:
undetectable
4fw0B-3rjyA:
undetectable		 4fw0A-3rjyA:
21.27
4fw0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4gqeA-3rjyA:
undetectable
4gqeB-3rjyA:
1.3		 4gqeA-3rjyA:
21.27
4gqeB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4gqeA-3rjyA:
undetectable
4gqeB-3rjyA:
1.2		 4gqeA-3rjyA:
21.27
4gqeB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 4imtA-3rjyA:
1.1
4imtB-3rjyA:
undetectable		 4imtA-3rjyA:
21.27
4imtB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4imuA-3rjyA:
1.4
4imuB-3rjyA:
undetectable		 4imuA-3rjyA:
21.27
4imuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4imuA-3rjyA:
1.4
4imuB-3rjyA:
undetectable		 4imuA-3rjyA:
21.27
4imuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4imwA-3rjyA:
1.4
4imwB-3rjyA:
1.3		 4imwA-3rjyA:
21.27
4imwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4jseA-3rjyA:
1.3
4jseB-3rjyA:
1.5		 4jseA-3rjyA:
21.27
4jseB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4jseA-3rjyA:
1.3
4jseB-3rjyA:
1.4		 4jseA-3rjyA:
21.27
4jseB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 4jsfA-3rjyA:
1.2
4jsfB-3rjyA:
undetectable		 4jsfA-3rjyA:
21.27
4jsfB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4jsfA-3rjyA:
1.2
4jsfB-3rjyA:
undetectable		 4jsfA-3rjyA:
21.27
4jsfB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4jsgA-3rjyA:
undetectable
4jsgB-3rjyA:
undetectable		 4jsgA-3rjyA:
21.27
4jsgB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4jsgA-3rjyA:
undetectable
4jsgB-3rjyA:
undetectable		 4jsgA-3rjyA:
21.27
4jsgB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4jshA-3rjyA:
undetectable
4jshB-3rjyA:
undetectable		 4jshA-3rjyA:
21.27
4jshB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.32A 4jshA-3rjyA:
undetectable
4jshB-3rjyA:
undetectable		 4jshA-3rjyA:
21.27
4jshB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 4jsiA-3rjyA:
undetectable
4jsiB-3rjyA:
0.9		 4jsiA-3rjyA:
21.27
4jsiB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 4jsiA-3rjyA:
undetectable
4jsiB-3rjyA:
1.0		 4jsiA-3rjyA:
21.27
4jsiB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4jsjA-3rjyA:
undetectable
4jsjB-3rjyA:
1.5		 4jsjA-3rjyA:
21.27
4jsjB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4jsjA-3rjyA:
undetectable
4jsjB-3rjyA:
undetectable		 4jsjA-3rjyA:
21.27
4jsjB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4k5dA-3rjyA:
1.4
4k5dB-3rjyA:
1.3		 4k5dA-3rjyA:
21.27
4k5dB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4k5dA-3rjyA:
undetectable
4k5dB-3rjyA:
1.2		 4k5dA-3rjyA:
21.27
4k5dB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 4k5eA-3rjyA:
undetectable
4k5eB-3rjyA:
1.2		 4k5eA-3rjyA:
21.27
4k5eB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4k5eA-3rjyA:
undetectable
4k5eB-3rjyA:
1.2		 4k5eA-3rjyA:
21.27
4k5eB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4k5fA-3rjyA:
1.1
4k5fB-3rjyA:
1.3		 4k5fA-3rjyA:
21.27
4k5fB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 4k5fA-3rjyA:
undetectable
4k5fB-3rjyA:
1.3		 4k5fA-3rjyA:
21.27
4k5fB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4k5gA-3rjyA:
undetectable
4k5gB-3rjyA:
undetectable		 4k5gA-3rjyA:
21.27
4k5gB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4k5gA-3rjyA:
undetectable
4k5gB-3rjyA:
undetectable		 4k5gA-3rjyA:
21.27
4k5gB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4kchA-3rjyA:
undetectable
4kchB-3rjyA:
undetectable		 4kchA-3rjyA:
21.27
4kchB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4kchA-3rjyA:
undetectable
4kchB-3rjyA:
undetectable		 4kchA-3rjyA:
21.27
4kchB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4kciA-3rjyA:
undetectable
4kciB-3rjyA:
undetectable		 4kciA-3rjyA:
21.27
4kciB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4kciA-3rjyA:
undetectable
4kciB-3rjyA:
undetectable		 4kciA-3rjyA:
21.27
4kciB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4kcjA-3rjyA:
undetectable
4kcjB-3rjyA:
undetectable		 4kcjA-3rjyA:
21.27
4kcjB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4kcjA-3rjyA:
undetectable
4kcjB-3rjyA:
undetectable		 4kcjA-3rjyA:
21.27
4kcjB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4kckA-3rjyA:
undetectable
4kckB-3rjyA:
1.3		 4kckA-3rjyA:
21.27
4kckB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 4kckA-3rjyA:
undetectable
4kckB-3rjyA:
1.4		 4kckA-3rjyA:
21.27
4kckB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4kclA-3rjyA:
undetectable
4kclB-3rjyA:
undetectable		 4kclA-3rjyA:
21.27
4kclB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4kclA-3rjyA:
undetectable
4kclB-3rjyA:
undetectable		 4kclA-3rjyA:
21.27
4kclB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4kcmA-3rjyA:
undetectable
4kcmB-3rjyA:
undetectable		 4kcmA-3rjyA:
21.27
4kcmB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4kcnA-3rjyA:
undetectable
4kcnB-3rjyA:
1.3		 4kcnA-3rjyA:
21.27
4kcnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4kcnA-3rjyA:
undetectable
4kcnB-3rjyA:
1.3		 4kcnA-3rjyA:
21.27
4kcnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4kcoA-3rjyA:
undetectable
4kcoB-3rjyA:
undetectable		 4kcoA-3rjyA:
21.27
4kcoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4kcoA-3rjyA:
undetectable
4kcoB-3rjyA:
undetectable		 4kcoA-3rjyA:
21.27
4kcoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4luxA-3rjyA:
undetectable
4luxB-3rjyA:
undetectable		 4luxA-3rjyA:
21.27
4luxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4luxA-3rjyA:
undetectable
4luxB-3rjyA:
undetectable		 4luxA-3rjyA:
21.27
4luxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TYR A 228
GLU A 317
GLU A 283
GLU A  54
 GLC  A 402 ( 3.4A)
PO4  A 404 ( 4.9A)
GLC  A 403 (-2.5A)
None
 1.00A 4mi4A-3rjyA:
0.9
4mi4C-3rjyA:
undetectable		 4mi4A-3rjyA:
19.75
4mi4C-3rjyA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		5 / 12 ASN A 192
ASP A 218
ILE A 122
ASN A 220
SER A 312
 None
 1.13A 4pooA-3rjyA:
2.1		 4pooA-3rjyA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		5 / 12 ASN A 192
ASP A 218
ILE A 122
ASN A 220
SER A 312
 None
 1.19A 4pooB-3rjyA:
undetectable		 4pooB-3rjyA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 4uchA-3rjyA:
undetectable
4uchB-3rjyA:
undetectable		 4uchA-3rjyA:
20.54
4uchB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4uchA-3rjyA:
undetectable
4uchB-3rjyA:
undetectable		 4uchA-3rjyA:
20.54
4uchB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 4ugzA-3rjyA:
undetectable
4ugzB-3rjyA:
undetectable		 4ugzA-3rjyA:
21.27
4ugzB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 4ugzA-3rjyA:
undetectable
4ugzB-3rjyA:
undetectable		 4ugzA-3rjyA:
21.27
4ugzB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 4uh0A-3rjyA:
1.5
4uh0B-3rjyA:
undetectable		 4uh0A-3rjyA:
21.27
4uh0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 4uh0A-3rjyA:
1.5
4uh0B-3rjyA:
undetectable		 4uh0A-3rjyA:
21.27
4uh0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4uh1A-3rjyA:
undetectable
4uh1B-3rjyA:
0.0		 4uh1A-3rjyA:
21.27
4uh1B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 4uh1A-3rjyA:
undetectable
4uh1B-3rjyA:
1.2		 4uh1A-3rjyA:
21.27
4uh1B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4uh2A-3rjyA:
undetectable
4uh2B-3rjyA:
undetectable		 4uh2A-3rjyA:
21.27
4uh2B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4uh2A-3rjyA:
undetectable
4uh2B-3rjyA:
undetectable		 4uh2A-3rjyA:
21.27
4uh2B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4uh3A-3rjyA:
1.3
4uh3B-3rjyA:
1.4		 4uh3A-3rjyA:
21.27
4uh3B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 4uh3A-3rjyA:
1.4
4uh3B-3rjyA:
1.4		 4uh3A-3rjyA:
21.27
4uh3B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4uh4A-3rjyA:
undetectable
4uh4B-3rjyA:
undetectable		 4uh4A-3rjyA:
21.27
4uh4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 4uh4A-3rjyA:
undetectable
4uh4B-3rjyA:
undetectable		 4uh4A-3rjyA:
21.27
4uh4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.24A 4uh5A-3rjyA:
undetectable
4uh5B-3rjyA:
undetectable		 4uh5A-3rjyA:
20.54
4uh5B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 4uh5A-3rjyA:
undetectable
4uh5B-3rjyA:
undetectable		 4uh5A-3rjyA:
20.54
4uh5B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 4uh6A-3rjyA:
1.4
4uh6B-3rjyA:
undetectable		 4uh6A-3rjyA:
20.54
4uh6B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 4uh6A-3rjyA:
1.4
4uh6B-3rjyA:
undetectable		 4uh6A-3rjyA:
20.54
4uh6B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4upmA-3rjyA:
undetectable
4upmB-3rjyA:
undetectable		 4upmA-3rjyA:
21.27
4upmB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4upmA-3rjyA:
undetectable
4upmB-3rjyA:
undetectable		 4upmA-3rjyA:
21.27
4upmB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 4upnA-3rjyA:
undetectable
4upnB-3rjyA:
undetectable		 4upnA-3rjyA:
21.27
4upnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4upnA-3rjyA:
undetectable
4upnB-3rjyA:
undetectable		 4upnA-3rjyA:
21.27
4upnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4upoA-3rjyA:
undetectable
4upoB-3rjyA:
1.1		 4upoA-3rjyA:
21.27
4upoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4upoA-3rjyA:
undetectable
4upoB-3rjyA:
1.0		 4upoA-3rjyA:
21.27
4upoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 4uppA-3rjyA:
undetectable
4uppB-3rjyA:
undetectable		 4uppA-3rjyA:
21.27
4uppB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4uppA-3rjyA:
undetectable
4uppB-3rjyA:
undetectable		 4uppA-3rjyA:
21.27
4uppB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.24A 4v3uA-3rjyA:
undetectable
4v3uB-3rjyA:
undetectable		 4v3uA-3rjyA:
20.78
4v3uB-3rjyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 4v3uA-3rjyA:
undetectable
4v3uB-3rjyA:
undetectable		 4v3uA-3rjyA:
20.78
4v3uB-3rjyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.23A 4v3uC-3rjyA:
1.1
4v3uD-3rjyA:
undetectable		 4v3uC-3rjyA:
20.78
4v3uD-3rjyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 4v3uC-3rjyA:
1.1
4v3uD-3rjyA:
undetectable		 4v3uC-3rjyA:
20.78
4v3uD-3rjyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4v3vA-3rjyA:
0.8
4v3vB-3rjyA:
undetectable		 4v3vA-3rjyA:
21.27
4v3vB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 4v3vA-3rjyA:
0.8
4v3vB-3rjyA:
undetectable		 4v3vA-3rjyA:
21.27
4v3vB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.34A 4v3wA-3rjyA:
1.5
4v3wB-3rjyA:
1.3		 4v3wA-3rjyA:
21.27
4v3wB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 4v3wA-3rjyA:
1.5
4v3wB-3rjyA:
1.2		 4v3wA-3rjyA:
21.27
4v3wB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4v3xA-3rjyA:
undetectable
4v3xB-3rjyA:
1.3		 4v3xA-3rjyA:
21.27
4v3xB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4v3xA-3rjyA:
undetectable
4v3xB-3rjyA:
1.3		 4v3xA-3rjyA:
21.27
4v3xB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 4v3yA-3rjyA:
undetectable
4v3yB-3rjyA:
undetectable		 4v3yA-3rjyA:
21.27
4v3yB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 4v3yA-3rjyA:
undetectable
4v3yB-3rjyA:
undetectable		 4v3yA-3rjyA:
21.27
4v3yB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 4v3zA-3rjyA:
undetectable
4v3zB-3rjyA:
undetectable		 4v3zA-3rjyA:
21.27
4v3zB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 ARG A  82
ILE A  83
ILE A 198
ASP A 200
 None
 1.20A 4w5qA-3rjyA:
undetectable		 4w5qA-3rjyA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 ARG A  82
ILE A  83
ILE A 198
ASP A 200
 None
 1.21A 4w5tA-3rjyA:
undetectable		 4w5tA-3rjyA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 ARG A  82
ILE A  83
ILE A 198
ASP A 200
 None
 1.15A 4z4dA-3rjyA:
2.7		 4z4dA-3rjyA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.34A 5ad4A-3rjyA:
undetectable
5ad4B-3rjyA:
undetectable		 5ad4A-3rjyA:
21.27
5ad4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.34A 5ad4A-3rjyA:
undetectable
5ad4B-3rjyA:
undetectable		 5ad4A-3rjyA:
21.27
5ad4B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 5ad5A-3rjyA:
undetectable
5ad5B-3rjyA:
undetectable		 5ad5A-3rjyA:
21.27
5ad5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 5ad5A-3rjyA:
undetectable
5ad5B-3rjyA:
undetectable		 5ad5A-3rjyA:
21.27
5ad5B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5ad6A-3rjyA:
1.4
5ad6B-3rjyA:
1.4		 5ad6A-3rjyA:
21.27
5ad6B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 5ad6A-3rjyA:
1.5
5ad6B-3rjyA:
1.2		 5ad6A-3rjyA:
21.27
5ad6B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5ad7A-3rjyA:
undetectable
5ad7B-3rjyA:
1.4		 5ad7A-3rjyA:
21.27
5ad7B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 5ad8A-3rjyA:
1.4
5ad8B-3rjyA:
0.9		 5ad8A-3rjyA:
21.27
5ad8B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5ad9A-3rjyA:
undetectable
5ad9B-3rjyA:
undetectable		 5ad9A-3rjyA:
21.27
5ad9B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5ad9A-3rjyA:
undetectable
5ad9B-3rjyA:
undetectable		 5ad9A-3rjyA:
21.27
5ad9B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.32A 5adaA-3rjyA:
1.1
5adaB-3rjyA:
undetectable		 5adaA-3rjyA:
21.27
5adaB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5adaA-3rjyA:
1.2
5adaB-3rjyA:
undetectable		 5adaA-3rjyA:
21.27
5adaB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.32A 5adbA-3rjyA:
undetectable
5adbB-3rjyA:
undetectable		 5adbA-3rjyA:
21.27
5adbB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5adcA-3rjyA:
1.4
5adcB-3rjyA:
undetectable		 5adcA-3rjyA:
21.27
5adcB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5adcA-3rjyA:
1.4
5adcB-3rjyA:
undetectable		 5adcA-3rjyA:
21.27
5adcB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.33A 5adeA-3rjyA:
undetectable
5adeB-3rjyA:
undetectable		 5adeA-3rjyA:
20.09
5adeB-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5adfA-3rjyA:
1.3
5adfB-3rjyA:
1.4		 5adfA-3rjyA:
20.54
5adfB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 5adgA-3rjyA:
1.5
5adgB-3rjyA:
undetectable		 5adgA-3rjyA:
20.54
5adgB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5adgA-3rjyA:
1.5
5adgB-3rjyA:
undetectable		 5adgA-3rjyA:
20.54
5adgB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5adiA-3rjyA:
undetectable
5adiB-3rjyA:
0.1		 5adiA-3rjyA:
20.54
5adiB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 5agkA-3rjyA:
undetectable
5agkB-3rjyA:
1.3		 5agkA-3rjyA:
21.27
5agkB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5agkA-3rjyA:
undetectable
5agkB-3rjyA:
1.3		 5agkA-3rjyA:
21.27
5agkB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 5aglA-3rjyA:
undetectable
5aglB-3rjyA:
undetectable		 5aglA-3rjyA:
21.27
5aglB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5aglA-3rjyA:
undetectable
5aglB-3rjyA:
undetectable		 5aglA-3rjyA:
21.27
5aglB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 5agmA-3rjyA:
undetectable
5agmB-3rjyA:
undetectable		 5agmA-3rjyA:
21.27
5agmB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5agmA-3rjyA:
undetectable
5agmB-3rjyA:
undetectable		 5agmA-3rjyA:
21.27
5agmB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.24A 5agnA-3rjyA:
undetectable
5agnB-3rjyA:
undetectable		 5agnA-3rjyA:
21.27
5agnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5agnA-3rjyA:
undetectable
5agnB-3rjyA:
undetectable		 5agnA-3rjyA:
21.27
5agnB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5agoA-3rjyA:
undetectable
5agoB-3rjyA:
0.0		 5agoA-3rjyA:
21.27
5agoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5agoA-3rjyA:
undetectable
5agoB-3rjyA:
0.0		 5agoA-3rjyA:
21.27
5agoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 5agpA-3rjyA:
undetectable
5agpB-3rjyA:
1.2		 5agpA-3rjyA:
21.27
5agpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 5agpA-3rjyA:
undetectable
5agpB-3rjyA:
1.4		 5agpA-3rjyA:
21.27
5agpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 4 VAL A 223
ILE A 164
ASN A 178
VAL A 216
 None
 1.08A 5ajqA-3rjyA:
undetectable		 5ajqA-3rjyA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5fvpA-3rjyA:
1.3
5fvpB-3rjyA:
undetectable		 5fvpA-3rjyA:
21.27
5fvpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.33A 5fvpA-3rjyA:
1.3
5fvpB-3rjyA:
undetectable		 5fvpA-3rjyA:
21.27
5fvpB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5fvqA-3rjyA:
undetectable
5fvqB-3rjyA:
undetectable		 5fvqA-3rjyA:
21.27
5fvqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5fvqA-3rjyA:
undetectable
5fvqB-3rjyA:
undetectable		 5fvqA-3rjyA:
21.27
5fvqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5fvrA-3rjyA:
undetectable
5fvrB-3rjyA:
undetectable		 5fvrA-3rjyA:
21.27
5fvrB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 5fvrA-3rjyA:
undetectable
5fvrB-3rjyA:
undetectable		 5fvrA-3rjyA:
21.27
5fvrB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5fvsA-3rjyA:
undetectable
5fvsB-3rjyA:
undetectable		 5fvsA-3rjyA:
21.27
5fvsB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 5fvsA-3rjyA:
undetectable
5fvsB-3rjyA:
undetectable		 5fvsA-3rjyA:
21.27
5fvsB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5fvtA-3rjyA:
undetectable
5fvtB-3rjyA:
undetectable		 5fvtA-3rjyA:
21.27
5fvtB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5fvtA-3rjyA:
undetectable
5fvtB-3rjyA:
undetectable		 5fvtA-3rjyA:
21.27
5fvtB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 5fvuA-3rjyA:
undetectable
5fvuB-3rjyA:
1.4		 5fvuA-3rjyA:
20.54
5fvuB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5fvuA-3rjyA:
undetectable
5fvuB-3rjyA:
1.5		 5fvuA-3rjyA:
20.54
5fvuB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 5fvvA-3rjyA:
undetectable
5fvvB-3rjyA:
1.1		 5fvvA-3rjyA:
20.54
5fvvB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.24A 5fvvA-3rjyA:
undetectable
5fvvB-3rjyA:
1.1		 5fvvA-3rjyA:
20.54
5fvvB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 5fvwA-3rjyA:
undetectable
5fvwB-3rjyA:
undetectable		 5fvwA-3rjyA:
20.54
5fvwB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5fvwA-3rjyA:
undetectable
5fvwB-3rjyA:
undetectable		 5fvwA-3rjyA:
20.54
5fvwB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 5fvxA-3rjyA:
undetectable
5fvxB-3rjyA:
1.4		 5fvxA-3rjyA:
20.54
5fvxB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5fw0A-3rjyA:
1.1
5fw0B-3rjyA:
undetectable		 5fw0A-3rjyA:
21.27
5fw0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 5fw0A-3rjyA:
1.2
5fw0B-3rjyA:
undetectable		 5fw0A-3rjyA:
21.27
5fw0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5g0nA-3rjyA:
undetectable
5g0nB-3rjyA:
undetectable		 5g0nA-3rjyA:
21.27
5g0nB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5g0nA-3rjyA:
undetectable
5g0nB-3rjyA:
undetectable		 5g0nA-3rjyA:
21.27
5g0nB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 5g0oA-3rjyA:
0.0
5g0oB-3rjyA:
undetectable		 5g0oA-3rjyA:
21.27
5g0oB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 5g0oA-3rjyA:
1.4
5g0oB-3rjyA:
undetectable		 5g0oA-3rjyA:
21.27
5g0oB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5g0pA-3rjyA:
undetectable
5g0pB-3rjyA:
undetectable		 5g0pA-3rjyA:
20.09
5g0pB-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 5g0pA-3rjyA:
undetectable
5g0pB-3rjyA:
undetectable		 5g0pA-3rjyA:
20.09
5g0pB-3rjyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		5 / 12 ILE A 122
ILE A 188
LEU A 185
VAL A 216
ILE A 199
 None
 1.09A 5mugA-3rjyA:
1.8		 5mugA-3rjyA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5unrA-3rjyA:
1.4
5unrB-3rjyA:
undetectable		 5unrA-3rjyA:
21.27
5unrB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 5unsA-3rjyA:
1.1
5unsB-3rjyA:
undetectable		 5unsA-3rjyA:
21.27
5unsB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 5unsA-3rjyA:
undetectable
5unsB-3rjyA:
undetectable		 5unsA-3rjyA:
21.27
5unsB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5untA-3rjyA:
0.0
5untB-3rjyA:
undetectable		 5untA-3rjyA:
21.27
5untB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 5untA-3rjyA:
0.0
5untB-3rjyA:
undetectable		 5untA-3rjyA:
21.27
5untB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.34A 5unuA-3rjyA:
1.4
5unuB-3rjyA:
undetectable		 5unuA-3rjyA:
21.27
5unuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.36A 5unuA-3rjyA:
1.3
5unuB-3rjyA:
undetectable		 5unuA-3rjyA:
21.27
5unuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.31A 5unvA-3rjyA:
1.0
5unvB-3rjyA:
0.8		 5unvA-3rjyA:
21.27
5unvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.33A 5unvA-3rjyA:
1.0
5unvB-3rjyA:
0.9		 5unvA-3rjyA:
21.27
5unvB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5unwA-3rjyA:
1.4
5unwB-3rjyA:
undetectable		 5unwA-3rjyA:
21.27
5unwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.32A 5unwA-3rjyA:
1.4
5unwB-3rjyA:
undetectable		 5unwA-3rjyA:
21.27
5unwB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.33A 5unxA-3rjyA:
1.5
5unxB-3rjyA:
1.4		 5unxA-3rjyA:
21.27
5unxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.35A 5unxA-3rjyA:
1.5
5unxB-3rjyA:
1.4		 5unxA-3rjyA:
21.27
5unxB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5unyA-3rjyA:
undetectable
5unyB-3rjyA:
undetectable		 5unyA-3rjyA:
21.27
5unyB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.32A 5unyA-3rjyA:
undetectable
5unyB-3rjyA:
undetectable		 5unyA-3rjyA:
21.27
5unyB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.33A 5unzA-3rjyA:
undetectable
5unzB-3rjyA:
0.9		 5unzA-3rjyA:
21.27
5unzB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.33A 5uo0A-3rjyA:
1.5
5uo0B-3rjyA:
0.9		 5uo0A-3rjyA:
21.27
5uo0B-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5uo1A-3rjyA:
1.4
5uo1B-3rjyA:
undetectable		 5uo1A-3rjyA:
20.54
5uo1B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 5uo1A-3rjyA:
undetectable
5uo1B-3rjyA:
undetectable		 5uo1A-3rjyA:
20.54
5uo1B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5uo2A-3rjyA:
1.4
5uo2B-3rjyA:
1.4		 5uo2A-3rjyA:
20.54
5uo2B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 5uo2A-3rjyA:
1.2
5uo2B-3rjyA:
1.4		 5uo2A-3rjyA:
20.54
5uo2B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5uo3A-3rjyA:
1.5
5uo3B-3rjyA:
undetectable		 5uo3A-3rjyA:
20.54
5uo3B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 5uo3A-3rjyA:
1.6
5uo3B-3rjyA:
undetectable		 5uo3A-3rjyA:
20.54
5uo3B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5uo4A-3rjyA:
1.6
5uo4B-3rjyA:
undetectable		 5uo4A-3rjyA:
20.54
5uo4B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 5uo4A-3rjyA:
1.6
5uo4B-3rjyA:
undetectable		 5uo4A-3rjyA:
20.54
5uo4B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5uo5A-3rjyA:
undetectable
5uo5B-3rjyA:
undetectable		 5uo5A-3rjyA:
20.54
5uo5B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5uo5A-3rjyA:
undetectable
5uo5B-3rjyA:
undetectable		 5uo5A-3rjyA:
20.54
5uo5B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5uo6A-3rjyA:
undetectable
5uo6B-3rjyA:
1.4		 5uo6A-3rjyA:
20.54
5uo6B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 8 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5uo7A-3rjyA:
1.4
5uo7B-3rjyA:
1.4		 5uo7A-3rjyA:
20.54
5uo7B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5uo7A-3rjyA:
1.4
5uo7B-3rjyA:
1.4		 5uo7A-3rjyA:
20.54
5uo7B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5vuiA-3rjyA:
1.3
5vuiB-3rjyA:
1.2		 5vuiA-3rjyA:
21.27
5vuiB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 5vuiA-3rjyA:
1.0
5vuiB-3rjyA:
1.2		 5vuiA-3rjyA:
21.27
5vuiB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5vujA-3rjyA:
1.1
5vujB-3rjyA:
undetectable		 5vujA-3rjyA:
21.27
5vujB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.33A 5vujA-3rjyA:
1.1
5vujB-3rjyA:
undetectable		 5vujA-3rjyA:
21.27
5vujB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 5vukA-3rjyA:
undetectable
5vukB-3rjyA:
undetectable		 5vukA-3rjyA:
21.27
5vukB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.31A 5vukA-3rjyA:
undetectable
5vukB-3rjyA:
undetectable		 5vukA-3rjyA:
21.27
5vukB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5vulA-3rjyA:
undetectable
5vulB-3rjyA:
undetectable		 5vulA-3rjyA:
21.27
5vulB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5vulA-3rjyA:
undetectable
5vulB-3rjyA:
undetectable		 5vulA-3rjyA:
21.27
5vulB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5vumA-3rjyA:
undetectable
5vumB-3rjyA:
undetectable		 5vumA-3rjyA:
21.27
5vumB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5vumA-3rjyA:
1.3
5vumB-3rjyA:
undetectable		 5vumA-3rjyA:
21.27
5vumB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5vunA-3rjyA:
undetectable
5vunB-3rjyA:
undetectable		 5vunA-3rjyA:
21.27
5vunB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 5vunA-3rjyA:
undetectable
5vunB-3rjyA:
undetectable		 5vunA-3rjyA:
21.27
5vunB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5vuoA-3rjyA:
undetectable
5vuoB-3rjyA:
undetectable		 5vuoA-3rjyA:
21.27
5vuoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5vuoA-3rjyA:
undetectable
5vuoB-3rjyA:
undetectable		 5vuoA-3rjyA:
21.27
5vuoB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 5vupA-3rjyA:
undetectable
5vupB-3rjyA:
1.3		 5vupA-3rjyA:
21.27
5vupB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 5vupA-3rjyA:
undetectable
5vupB-3rjyA:
1.3		 5vupA-3rjyA:
21.27
5vupB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5vuqA-3rjyA:
undetectable
5vuqB-3rjyA:
undetectable		 5vuqA-3rjyA:
21.27
5vuqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 5vuqA-3rjyA:
undetectable
5vuqB-3rjyA:
undetectable		 5vuqA-3rjyA:
21.27
5vuqB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.33A 5vusA-3rjyA:
1.4
5vusB-3rjyA:
undetectable		 5vusA-3rjyA:
21.27
5vusB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 5vusA-3rjyA:
1.4
5vusB-3rjyA:
undetectable		 5vusA-3rjyA:
21.27
5vusB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5vutA-3rjyA:
undetectable
5vutB-3rjyA:
undetectable		 5vutA-3rjyA:
21.27
5vutB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 5vutA-3rjyA:
undetectable
5vutB-3rjyA:
undetectable		 5vutA-3rjyA:
21.27
5vutB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.32A 5vuuA-3rjyA:
undetectable
5vuuB-3rjyA:
undetectable		 5vuuA-3rjyA:
21.27
5vuuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 5vuuA-3rjyA:
undetectable
5vuuB-3rjyA:
undetectable		 5vuuA-3rjyA:
21.27
5vuuB-3rjyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 5vuvA-3rjyA:
undetectable
5vuvB-3rjyA:
undetectable		 5vuvA-3rjyA:
20.54
5vuvB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 5vuvA-3rjyA:
undetectable
5vuvB-3rjyA:
undetectable		 5vuvA-3rjyA:
20.54
5vuvB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 5vuwA-3rjyA:
1.5
5vuwB-3rjyA:
undetectable		 5vuwA-3rjyA:
20.54
5vuwB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 5vuwA-3rjyA:
1.5
5vuwB-3rjyA:
undetectable		 5vuwA-3rjyA:
20.54
5vuwB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5vuxA-3rjyA:
1.5
5vuxB-3rjyA:
1.0		 5vuxA-3rjyA:
20.54
5vuxB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.26A 5vuyA-3rjyA:
1.4
5vuyB-3rjyA:
undetectable		 5vuyA-3rjyA:
20.54
5vuyB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 5vuyA-3rjyA:
1.4
5vuyB-3rjyA:
undetectable		 5vuyA-3rjyA:
20.54
5vuyB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5vuzA-3rjyA:
undetectable
5vuzB-3rjyA:
undetectable		 5vuzA-3rjyA:
20.54
5vuzB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5vuzA-3rjyA:
undetectable
5vuzB-3rjyA:
undetectable		 5vuzA-3rjyA:
20.54
5vuzB-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5vv0A-3rjyA:
undetectable
5vv0B-3rjyA:
undetectable		 5vv0A-3rjyA:
20.67
5vv0B-3rjyA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5vv0A-3rjyA:
undetectable
5vv0B-3rjyA:
undetectable		 5vv0A-3rjyA:
20.67
5vv0B-3rjyA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 5vv1A-3rjyA:
undetectable
5vv1B-3rjyA:
1.3		 5vv1A-3rjyA:
20.54
5vv1B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5vv1A-3rjyA:
undetectable
5vv1B-3rjyA:
1.4		 5vv1A-3rjyA:
20.54
5vv1B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 5vv2A-3rjyA:
undetectable
5vv2B-3rjyA:
undetectable		 5vv2A-3rjyA:
20.54
5vv2B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5vv2A-3rjyA:
undetectable
5vv2B-3rjyA:
undetectable		 5vv2A-3rjyA:
20.54
5vv2B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 5vv3A-3rjyA:
undetectable
5vv3B-3rjyA:
undetectable		 5vv3A-3rjyA:
20.54
5vv3B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 5vv3A-3rjyA:
undetectable
5vv3B-3rjyA:
undetectable		 5vv3A-3rjyA:
20.54
5vv3B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 5vv4A-3rjyA:
1.4
5vv4B-3rjyA:
0.9		 5vv4A-3rjyA:
20.54
5vv4B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 5vv5A-3rjyA:
1.3
5vv5B-3rjyA:
1.3		 5vv5A-3rjyA:
20.54
5vv5B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 5vv5A-3rjyA:
1.2
5vv5B-3rjyA:
1.3		 5vv5A-3rjyA:
20.54
5vv5B-3rjyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		3 / 3 LYS A 343
LEU A 313
ASP A  79
 None
 0.68A 5zv2A-3rjyA:
undetectable		 5zv2A-3rjyA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 6auqA-3rjyA:
undetectable
6auqB-3rjyA:
undetectable		 6auqA-3rjyA:
14.43
6auqB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.32A 6auqA-3rjyA:
undetectable
6auqB-3rjyA:
undetectable		 6auqA-3rjyA:
14.43
6auqB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 6aurA-3rjyA:
undetectable
6aurB-3rjyA:
undetectable		 6aurA-3rjyA:
14.43
6aurB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 6aurA-3rjyA:
undetectable
6aurB-3rjyA:
undetectable		 6aurA-3rjyA:
14.43
6aurB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 6ausA-3rjyA:
undetectable
6ausB-3rjyA:
undetectable		 6ausA-3rjyA:
14.43
6ausB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 6ausA-3rjyA:
undetectable
6ausB-3rjyA:
undetectable		 6ausA-3rjyA:
14.43
6ausB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 6autA-3rjyA:
undetectable
6autB-3rjyA:
undetectable		 6autA-3rjyA:
14.43
6autB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 6autA-3rjyA:
undetectable
6autB-3rjyA:
undetectable		 6autA-3rjyA:
14.43
6autB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 6auuA-3rjyA:
1.5
6auuB-3rjyA:
undetectable		 6auuA-3rjyA:
14.43
6auuB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.29A 6auuA-3rjyA:
1.5
6auuB-3rjyA:
undetectable		 6auuA-3rjyA:
14.43
6auuB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 6auvA-3rjyA:
undetectable
6auvB-3rjyA:
1.5		 6auvA-3rjyA:
14.43
6auvB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 6auvA-3rjyA:
undetectable
6auvB-3rjyA:
1.5		 6auvA-3rjyA:
14.43
6auvB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 6auwA-3rjyA:
0.6
6auwB-3rjyA:
undetectable		 6auwA-3rjyA:
14.43
6auwB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 6auwA-3rjyA:
0.6
6auwB-3rjyA:
undetectable		 6auwA-3rjyA:
14.43
6auwB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 6auxA-3rjyA:
undetectable
6auxB-3rjyA:
undetectable		 6auxA-3rjyA:
14.43
6auxB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.30A 6auxA-3rjyA:
undetectable
6auxB-3rjyA:
undetectable		 6auxA-3rjyA:
14.43
6auxB-3rjyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 6auyA-3rjyA:
undetectable
6auyB-3rjyA:
undetectable		 6auyA-3rjyA:
13.75
6auyB-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 6auyA-3rjyA:
undetectable
6auyB-3rjyA:
undetectable		 6auyA-3rjyA:
13.75
6auyB-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 6auzA-3rjyA:
1.5
6auzB-3rjyA:
undetectable		 6auzA-3rjyA:
13.75
6auzB-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.25A 6auzA-3rjyA:
1.5
6auzB-3rjyA:
1.4		 6auzA-3rjyA:
13.75
6auzB-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 6av0A-3rjyA:
1.6
6av0B-3rjyA:
1.4		 6av0A-3rjyA:
13.75
6av0B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.23A 6av0A-3rjyA:
1.6
6av0B-3rjyA:
1.4		 6av0A-3rjyA:
13.75
6av0B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 6av1A-3rjyA:
1.2
6av1B-3rjyA:
undetectable		 6av1A-3rjyA:
13.75
6av1B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.33A 6av1A-3rjyA:
1.2
6av1B-3rjyA:
undetectable		 6av1A-3rjyA:
13.75
6av1B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.30A 6av2A-3rjyA:
1.4
6av2B-3rjyA:
1.4		 6av2A-3rjyA:
13.75
6av2B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 6av2A-3rjyA:
1.4
6av2B-3rjyA:
1.4		 6av2A-3rjyA:
13.75
6av2B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.24A 6av3A-3rjyA:
1.2
6av3B-3rjyA:
1.5		 6av3A-3rjyA:
13.75
6av3B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.25A 6av4A-3rjyA:
undetectable
6av4B-3rjyA:
undetectable		 6av4A-3rjyA:
13.75
6av4B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.26A 6av4A-3rjyA:
undetectable
6av4B-3rjyA:
undetectable		 6av4A-3rjyA:
13.75
6av4B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.28A 6av5A-3rjyA:
0.4
6av5B-3rjyA:
undetectable		 6av5A-3rjyA:
13.75
6av5B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 6av5A-3rjyA:
0.4
6av5B-3rjyA:
undetectable		 6av5A-3rjyA:
13.75
6av5B-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 6 ARG A  82
ILE A  83
ILE A 198
ASP A 200
 None
 1.14A 6cbdA-3rjyA:
undetectable		 6cbdA-3rjyA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 ILE A 145
GLN A 148
VAL A 149
ILE A  85
 None
 0.98A 6cduF-3rjyA:
undetectable
6cduG-3rjyA:
undetectable		 6cduF-3rjyA:
22.64
6cduG-3rjyA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.29A 6cicA-3rjyA:
undetectable
6cicB-3rjyA:
undetectable		 6cicA-3rjyA:
13.75
6cicB-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.27A 6cicA-3rjyA:
undetectable
6cicB-3rjyA:
undetectable		 6cicA-3rjyA:
13.75
6cicB-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 VAL A 149
TRP A 146
PHE A 162
GLU A 187
 None
 1.27A 6cidA-3rjyA:
undetectable
6cidB-3rjyA:
undetectable		 6cidA-3rjyA:
13.75
6cidB-3rjyA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rjy ENDOGLUCANASE
FNCEL5A
(Fervidobacterium
nodosum) 		4 / 7 TRP A 146
PHE A 162
GLU A 187
VAL A 149
 None
 1.28A 6cidA-3rjyA:
undetectable
6cidB-3rjyA:
undetectable		 6cidA-3rjyA:
13.75
6cidB-3rjyA:
13.75