SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PNC_A_CLUA808_1 (COPPER AMINE OXIDASE, LIVER ISOZYME)	3rjz	N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY (Pyrococcus furiosus)	4 / 7	ALA A 181 TYR A 131 ASP A 16 HIS A 179	None	1.44A	2pncA-3rjzA: undetectable	2pncA-3rjzA: 14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VE3_B_REAB1445_1 (PUTATIVE CYTOCHROME P450 120)	3rjz	N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY (Pyrococcus furiosus)	5 / 12	PHE A 197 ALA A 123 PHE A 140 ALA A 181 GLN A 58	None	1.22A	2ve3B-3rjzA: undetectable	2ve3B-3rjzA: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IB4_A_ERMA2001_1 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562)	3rjz	N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY (Pyrococcus furiosus)	5 / 12	LEU A 117 VAL A 7 VAL A 111 ALA A 24 VAL A 35	None	1.26A	4ib4A-3rjzA: undetectable	4ib4A-3rjzA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NC3_A_ERMA1202_1 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562)	3rjz	N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY (Pyrococcus furiosus)	5 / 12	LEU A 117 VAL A 7 VAL A 111 ALA A 24 VAL A 35	None	1.23A	4nc3A-3rjzA: undetectable	4nc3A-3rjzA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZF8_A_MYTA502_1 (BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE)	3rjz	N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY (Pyrococcus furiosus)	4 / 6	VAL A 9 LEU A 196 ILE A 25 ALA A 24	None	0.74A	4zf8A-3rjzA: undetectable	4zf8A-3rjzA: 21.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2PNC_A_CLUA808_1","COPPER AMINE OXIDASE, LIVER ISOZYME","3rjz","N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY","Pyrococcus furiosus",4,"ALA A 181;TYR A 131;ASP A  16;HIS A 179","None","1.44A","2pncA-3rjzA:undetectable","2pncA-3rjzA:14.56"],["2VE3_B_REAB1445_1","PUTATIVE CYTOCHROME P450 120","3rjz","N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY","Pyrococcus furiosus",5,"PHE A 197;ALA A 123;PHE A 140;ALA A 181;GLN A  58","None","1.22A","2ve3B-3rjzA:undetectable","2ve3B-3rjzA:21.75"],["4IB4_A_ERMA2001_1","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562","3rjz","N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY","Pyrococcus furiosus",5,"LEU A 117;VAL A   7;VAL A 111;ALA A  24;VAL A  35","None","1.26A","4ib4A-3rjzA:undetectable","4ib4A-3rjzA:19.35"],["4NC3_A_ERMA1202_1","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562","3rjz","N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY","Pyrococcus furiosus",5,"LEU A 117;VAL A   7;VAL A 111;ALA A  24;VAL A  35","None","1.23A","4nc3A-3rjzA:undetectable","4nc3A-3rjzA:19.35"],["4ZF8_A_MYTA502_1","BIFUNCTIONAL P-450\/NADPH-P450 REDUCTASE","3rjz","N-TYPE ATP PYROPHOSPHATASE SUPERFAMILY","Pyrococcus furiosus",4,"VAL A   9;LEU A 196;ILE A  25;ALA A  24","None","0.74A","4zf8A-3rjzA:undetectable","4zf8A-3rjzA:21.23"]]