SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rkg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N5X_A_TEIA3006_1 (XANTHINE DEHYDROGENASE)	3rkg	MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 12	LEU A 160 LEU A 156 THR A 67 VAL A 68 ALA A 128	None	1.17A	1n5xA-3rkgA: 3.1	1n5xA-3rkgA: 11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N5X_B_TEIB4006_1 (XANTHINE DEHYDROGENASE)	3rkg	MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 12	LEU A 160 LEU A 156 THR A 67 VAL A 68 ALA A 128	None	1.17A	1n5xB-3rkgA: undetectable	1n5xB-3rkgA: 11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PD9_A_ADNA501_2 (NUPC FAMILY PROTEIN)	3rkg	MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL (Saccharomyces cerevisiae)	3 / 3	THR A 253 ASN A 70 PHE A 69	None	0.79A	4pd9A-3rkgA: undetectable	4pd9A-3rkgA: 18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWV_A_ACAA18_2 (SCRFP-TAG,GP41)	3rkg	MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 7	GLN A 228 LEU A 225 ASP A 222 LEU A 216	None	1.03A	5nwvA-3rkgA: undetectable	5nwvA-3rkgA: 9.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1N5X_A_TEIA3006_1","XANTHINE DEHYDROGENASE","3rkg","MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL","Saccharomyces cerevisiae",5,"LEU A 160;LEU A 156;THR A  67;VAL A  68;ALA A 128","None","1.17A","1n5xA-3rkgA:3.1","1n5xA-3rkgA:11.94"],["1N5X_B_TEIB4006_1","XANTHINE DEHYDROGENASE","3rkg","MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL","Saccharomyces cerevisiae",5,"LEU A 160;LEU A 156;THR A  67;VAL A  68;ALA A 128","None","1.17A","1n5xB-3rkgA:undetectable","1n5xB-3rkgA:11.94"],["4PD9_A_ADNA501_2","NUPC FAMILY PROTEIN","3rkg","MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL","Saccharomyces cerevisiae",3,"THR A 253;ASN A  70;PHE A  69","None","0.79A","4pd9A-3rkgA:undetectable","4pd9A-3rkgA:18.20"],["5NWV_A_ACAA18_2","SCRFP-TAG,GP41","3rkg","MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL","Saccharomyces cerevisiae",4,"GLN A 228;LEU A 225;ASP A 222;LEU A 216","None","1.03A","5nwvA-3rkgA:undetectable","5nwvA-3rkgA:9.56"]]