SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rkr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		5 / 12 LEU A 163
LEU A 166
GLY A 165
ALA A 145
LEU A 144
 None
 1.09A 2oz7A-3rkrA:
undetectable		 2oz7A-3rkrA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		5 / 12 ILE A  22
ALA A  21
GLY A  17
ILE A 212
GLY A  13
 None
None
SO4  A 242 (-3.6A)
None
NAP  A 240 (-3.4A)
 0.82A 2qe6A-3rkrA:
5.6		 2qe6A-3rkrA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		5 / 12 ILE A  22
ALA A  21
GLY A  17
ILE A 212
GLY A  13
 None
None
SO4  A 242 (-3.6A)
None
NAP  A 240 (-3.4A)
 0.86A 2qe6B-3rkrA:
6.2		 2qe6B-3rkrA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		4 / 7 ALA A 213
ALA A 217
THR A 221
LEU A   4
 None
 0.74A 2wx2A-3rkrA:
undetectable		 2wx2A-3rkrA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		4 / 6 VAL A  88
LEU A 121
ILE A 212
ILE A 139
 None
 0.85A 3gcsA-3rkrA:
undetectable		 3gcsA-3rkrA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		4 / 8 ALA A 213
ALA A 217
THR A 221
LEU A   4
 None
 0.70A 3khmA-3rkrA:
undetectable		 3khmA-3rkrA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		4 / 8 ALA A 213
ALA A 217
THR A 221
LEU A   4
 None
 0.64A 3l4dA-3rkrA:
undetectable		 3l4dA-3rkrA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		5 / 12 ILE A 141
SER A 182
GLN A   7
LEU A   4
LEU A  26
 None
 1.37A 4qztA-3rkrA:
undetectable		 4qztA-3rkrA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		4 / 7 ALA A 118
SER A 143
GLY A  92
ALA A  91
 None
None
NAP  A 240 (-4.5A)
NAP  A 240 (-3.6A)
 0.87A 4r1zB-3rkrA:
undetectable		 4r1zB-3rkrA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		3 / 3 MET A 103
GLU A 107
LEU A 111
 None
 0.58A 4v2oB-3rkrA:
undetectable		 4v2oB-3rkrA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		5 / 12 THR A  36
VAL A  10
VAL A  88
ASP A  63
VAL A 114
 None
None
None
NAP  A 240 (-3.8A)
None
 1.27A 6iblA-3rkrA:
undetectable		 6iblA-3rkrA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3rkr SHORT CHAIN
OXIDOREDUCTASE
(uncultured
bacterium
Bio5) 		5 / 12 THR A  36
VAL A  10
VAL A  88
ASP A  63
VAL A 114
 None
None
None
NAP  A 240 (-3.8A)
None
 1.29A 6iblB-3rkrA:
undetectable		 6iblB-3rkrA:
20.57