SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rmh YEAST CDC13 OB4
([Candida]
glabrata) 		5 / 12 PHE A 696
LEU A 706
VAL A 655
PHE A 685
CYH A 726
 None
 1.24A 3u9fD-3rmhA:
undetectable
3u9fE-3rmhA:
undetectable		 3u9fD-3rmhA:
20.56
3u9fE-3rmhA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rmh YEAST CDC13 OB4
([Candida]
glabrata) 		5 / 12 PHE A 696
LEU A 706
VAL A 655
PHE A 685
CYH A 726
 None
 1.26A 3u9fG-3rmhA:
undetectable
3u9fH-3rmhA:
undetectable		 3u9fG-3rmhA:
20.56
3u9fH-3rmhA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rmh YEAST CDC13 OB4
([Candida]
glabrata) 		5 / 12 PHE A 685
CYH A 726
PHE A 696
LEU A 706
VAL A 655
 None
 1.24A 3u9fP-3rmhA:
undetectable
3u9fS-3rmhA:
undetectable		 3u9fP-3rmhA:
20.56
3u9fS-3rmhA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3rmh YEAST CDC13 OB4
([Candida]
glabrata) 		4 / 6 SER A 722
ARG A 652
GLU A 650
TYR A 675
 None
 1.28A 5x7pA-3rmhA:
undetectable		 5x7pA-3rmhA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3rmh YEAST CDC13 OB4
([Candida]
glabrata) 		4 / 6 SER A 722
ARG A 652
GLU A 650
TYR A 675
 None
 1.25A 5x7qA-3rmhA:
undetectable		 5x7qA-3rmhA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3rmh YEAST CDC13 OB4
([Candida]
glabrata) 		4 / 6 SER A 722
ARG A 652
GLU A 650
TYR A 675
 None
 1.31A 5x7qB-3rmhA:
undetectable		 5x7qB-3rmhA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3rmh YEAST CDC13 OB4
([Candida]
glabrata) 		4 / 6 SER A 722
ARG A 652
GLU A 650
TYR A 675
 None
 1.24A 5x7rA-3rmhA:
undetectable		 5x7rA-3rmhA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3rmh YEAST CDC13 OB4
([Candida]
glabrata) 		4 / 6 SER A 722
ARG A 652
GLU A 650
TYR A 675
 None
 1.32A 5x7rB-3rmhA:
undetectable		 5x7rB-3rmhA:
7.58