SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rmr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_G_SVRG506_1 (PHOSPHOLIPASE A2)	3rmr	AVIRULENCE PROTEIN (Hyaloperonospora parasitica)	4 / 8	VAL A 94 VAL A 95 LYS A 99 LYS A 90	None	0.69A	3bjwA-3rmrA: undetectable	3bjwA-3rmrA: 17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LSU_B_SAMB1304_1 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD2)	3rmr	AVIRULENCE PROTEIN (Hyaloperonospora parasitica)	3 / 3	ASN A 216 TYR A 230 CYH A 258	None	0.81A	5lsuB-3rmrA: undetectable	5lsuB-3rmrA: 18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_C_SAMC1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rmr	AVIRULENCE PROTEIN (Hyaloperonospora parasitica)	5 / 12	ASN A 216 TYR A 230 PHE A 231 CYH A 258 GLN A 257	None	1.35A	5ttfC-3rmrA: undetectable	5ttfC-3rmrA: 20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TWJ_B_SAMB201_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H)	3rmr	AVIRULENCE PROTEIN (Hyaloperonospora parasitica)	5 / 10	LEU A 107 ILE A 111 GLY A 112 HIS A 114 VAL A 70	None	1.04A	5twjB-3rmrA: undetectable	5twjB-3rmrA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CI6_A_NBOA607_1 (SERUM ALBUMIN)	3rmr	AVIRULENCE PROTEIN (Hyaloperonospora parasitica)	4 / 7	ASP A 213 ASN A 217 ALA A 215 GLU A 210	None	1.07A	6ci6A-3rmrA: 2.7	6ci6A-3rmrA: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BJW_G_SVRG506_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","3rmr","AVIRULENCE PROTEIN","Hyaloperonospora parasitica",4,"VAL A  94;VAL A  95;LYS A  99;LYS A  90","None","0.69A","3bjwA-3rmrA:undetectable","3bjwA-3rmrA:17.34"],["5LSU_B_SAMB1304_1","HISTONE-LYSINE N-METHYLTRANSFERASE NSD2","3rmr","AVIRULENCE PROTEIN","Hyaloperonospora parasitica",3,"ASN A 216;TYR A 230;CYH A 258","None","0.81A","5lsuB-3rmrA:undetectable","5lsuB-3rmrA:18.70"],["5TTF_C_SAMC1505_0","HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2","3rmr","AVIRULENCE PROTEIN","Hyaloperonospora parasitica",5,"ASN A 216;TYR A 230;PHE A 231;CYH A 258;GLN A 257","None","1.35A","5ttfC-3rmrA:undetectable","5ttfC-3rmrA:20.46"],["5TWJ_B_SAMB201_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H","3rmr","AVIRULENCE PROTEIN","Hyaloperonospora parasitica",5,"LEU A 107;ILE A 111;GLY A 112;HIS A 114;VAL A  70","None","1.04A","5twjB-3rmrA:undetectable","5twjB-3rmrA:20.07"],["6CI6_A_NBOA607_1","SERUM ALBUMIN","3rmr","AVIRULENCE PROTEIN","Hyaloperonospora parasitica",4,"ASP A 213;ASN A 217;ALA A 215;GLU A 210","None","1.07A","6ci6A-3rmrA:2.7","6ci6A-3rmrA:21.43"]]