SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rms'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3rms UNCHARACTERIZED
PROTEIN
(Saccharomonospor
a
viridis) 		3 / 3 TRP A   6
TYR A  16
LEU A  32
 None
None
GOL  A 115 (-4.8A)
 1.00A 1kxhA-3rmsA:
undetectable		 1kxhA-3rmsA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 3rms UNCHARACTERIZED
PROTEIN
(Saccharomonospor
a
viridis) 		5 / 12 THR A 106
VAL A 102
LEU A 105
LEU A  95
LEU A  32
 None
None
None
None
GOL  A 115 (-4.8A)
 1.23A 1mx1C-3rmsA:
undetectable		 1mx1C-3rmsA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3rms UNCHARACTERIZED
PROTEIN
(Saccharomonospor
a
viridis) 		5 / 8 ALA A  64
ALA A  78
LEU A 105
LEU A  95
ALA A  62
 None
 1.16A 4z90A-3rmsA:
undetectable
4z90B-3rmsA:
undetectable
4z90C-3rmsA:
undetectable
4z90D-3rmsA:
undetectable
4z90E-3rmsA:
undetectable		 4z90A-3rmsA:
16.29
4z90B-3rmsA:
16.29
4z90C-3rmsA:
16.29
4z90D-3rmsA:
16.29
4z90E-3rmsA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3rms UNCHARACTERIZED
PROTEIN
(Saccharomonospor
a
viridis) 		5 / 7 LEU A 105
LEU A  95
ALA A  62
ALA A  64
ALA A  78
 None
 1.12A 4z90F-3rmsA:
undetectable
4z90G-3rmsA:
undetectable
4z90H-3rmsA:
undetectable
4z90J-3rmsA:
undetectable		 4z90F-3rmsA:
16.29
4z90G-3rmsA:
16.29
4z90H-3rmsA:
16.29
4z90J-3rmsA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3rms UNCHARACTERIZED
PROTEIN
(Saccharomonospor
a
viridis) 		4 / 8 ALA A  78
PRO A  57
LEU A  91
LEU A  87
 None
 0.70A 5dzkd-3rmsA:
undetectable
5dzkr-3rmsA:
undetectable		 5dzkd-3rmsA:
18.60
5dzkr-3rmsA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3rms UNCHARACTERIZED
PROTEIN
(Saccharomonospor
a
viridis) 		4 / 8 ALA A  78
PRO A  57
LEU A  91
LEU A  87
 None
 0.83A 5dzkF-3rmsA:
undetectable
5dzkT-3rmsA:
undetectable		 5dzkF-3rmsA:
18.60
5dzkT-3rmsA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3rms UNCHARACTERIZED
PROTEIN
(Saccharomonospor
a
viridis) 		3 / 3 TRP A  83
ILE A  61
GLU A  55
 None
 0.66A 6hcxA-3rmsA:
undetectable		 6hcxA-3rmsA:
19.23