SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rmt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 10 PHE A  47
VAL A 233
ARG A  73
PRO A 234
GLY A  23
 None
 1.46A 13gsA-3rmtA:
undetectable		 13gsA-3rmtA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_B_SASB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 9 PHE A  47
VAL A 233
ARG A  73
PRO A 234
GLY A  23
 None
 1.46A 13gsB-3rmtA:
undetectable		 13gsB-3rmtA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.15A 1ddsA-3rmtA:
undetectable		 1ddsA-3rmtA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.09A 1dyiA-3rmtA:
undetectable		 1dyiA-3rmtA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.08A 1dyiB-3rmtA:
undetectable		 1dyiB-3rmtA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 11 ARG A 125
SER A  96
GLY A  97
ARG A 101
ASP A  52
 SO4  A 500 ( 2.9A)
SO4  A 500 ( 4.0A)
SO4  A 500 (-3.4A)
SO4  A 505 (-3.0A)
SO4  A 504 (-3.4A)
 1.47A 1ho5A-3rmtA:
undetectable		 1ho5A-3rmtA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.01A 1rd7B-3rmtA:
undetectable		 1rd7B-3rmtA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.02A 1re7A-3rmtA:
undetectable		 1re7A-3rmtA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 LEU A 379
LEU A 403
ILE A 373
THR A 334
ILE A 399
 None
 1.24A 1tw4B-3rmtA:
undetectable		 1tw4B-3rmtA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ALA A 396
ALA A 398
VAL A  21
HIS A 426
LEU A 427
 None
 0.98A 1xiuB-3rmtA:
undetectable		 1xiuB-3rmtA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 11 THR A  56
GLY A  35
THR A  42
VAL A  44
VAL A 231
 None
 1.23A 2a1nA-3rmtA:
undetectable		 2a1nA-3rmtA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 5 LEU A 257
PRO A  22
VAL A  21
ILE A  19
 None
 0.86A 2aoiB-3rmtA:
undetectable		 2aoiB-3rmtA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 GLY A 138
ALA A 139
ILE A 154
ILE A 177
ILE A 141
 None
 0.96A 2hs1A-3rmtA:
undetectable		 2hs1A-3rmtA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 9 VAL A  21
GLY A 235
LEU A 296
LEU A 270
ASP A 236
 None
 1.22A 2j2pB-3rmtA:
undetectable
2j2pC-3rmtA:
undetectable		 2j2pB-3rmtA:
17.52
2j2pC-3rmtA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 5 SER A 166
VAL A 190
SER A 170
VAL A 168
 None
 1.22A 2j9cA-3rmtA:
undetectable
2j9cB-3rmtA:
undetectable
2j9cC-3rmtA:
undetectable		 2j9cA-3rmtA:
14.73
2j9cB-3rmtA:
14.73
2j9cC-3rmtA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 9 GLY A 156
LEU A 110
THR A 109
LEU A  91
LEU A 134
 None
 1.19A 2npnA-3rmtA:
undetectable		 2npnA-3rmtA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 THR A 109
ILE A 106
GLY A 105
GLY A 181
LEU A 182
 None
 1.06A 2y7kD-3rmtA:
undetectable		 2y7kD-3rmtA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 6 ARG A 197
ASP A 318
ILE A 320
GLU A 346
 SO4  A 507 (-3.8A)
None
None
None
 1.44A 2ya7C-3rmtA:
undetectable		 2ya7C-3rmtA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 PHE A 423
THR A   7
ILE A   9
PRO A  10
ILE A 416
 None
None
None
SO4  A 456 (-4.4A)
None
 1.13A 3clbB-3rmtA:
undetectable		 3clbB-3rmtA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 9 ALA A 396
LEU A 357
VAL A 245
ILE A 373
ILE A 323
 None
 1.15A 3jw3B-3rmtA:
undetectable		 3jw3B-3rmtA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		3 / 3 SER A  96
GLY A  97
THR A  98
 SO4  A 500 ( 4.0A)
SO4  A 500 (-3.4A)
SO4  A 507 (-3.6A)
 0.17A 3k9wA-3rmtA:
undetectable		 3k9wA-3rmtA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 10 THR A  56
GLY A  35
THR A  42
VAL A  44
VAL A 231
 None
 1.19A 3lxiA-3rmtA:
undetectable		 3lxiA-3rmtA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 10 THR A  56
GLY A  35
THR A  42
VAL A  74
VAL A  44
 None
 1.24A 3lxiA-3rmtA:
undetectable		 3lxiA-3rmtA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 11 THR A  56
GLY A  35
THR A  42
VAL A  44
VAL A 231
 None
 1.20A 3lxiB-3rmtA:
undetectable		 3lxiB-3rmtA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 11 THR A  56
GLY A  35
THR A  42
VAL A  74
VAL A  44
 None
 1.19A 3lxiB-3rmtA:
undetectable		 3lxiB-3rmtA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 10 GLY A 138
ALA A 139
ILE A 154
ILE A 177
ILE A 141
 None
 1.01A 3s43B-3rmtA:
undetectable		 3s43B-3rmtA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 THR A 413
ILE A 416
SER A 419
ILE A  19
ASP A 428
 None
 1.22A 3vw1D-3rmtA:
undetectable		 3vw1D-3rmtA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 6 GLY A 268
ARG A 202
ILE A 237
LEU A 273
 None
 1.15A 4ac9C-3rmtA:
undetectable		 4ac9C-3rmtA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 9 ASP A 119
ILE A 122
GLY A  94
THR A 100
ARG A 197
 SO4  A 506 (-4.6A)
None
None
None
SO4  A 507 (-3.8A)
 1.42A 4acaB-3rmtA:
undetectable
4acaC-3rmtA:
undetectable		 4acaB-3rmtA:
24.40
4acaC-3rmtA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 6 GLY A 268
ARG A 202
ILE A 237
LEU A 273
 None
 1.17A 4acaC-3rmtA:
undetectable		 4acaC-3rmtA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 9 PRO A 321
VAL A 325
LEU A 357
LEU A 360
ILE A 393
 None
 1.24A 4c66A-3rmtA:
undetectable		 4c66A-3rmtA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 10 MET A 203
ALA A  38
LEU A 226
GLY A 208
ALA A 139
 None
 1.07A 4fe1A-3rmtA:
undetectable
4fe1J-3rmtA:
undetectable		 4fe1A-3rmtA:
20.92
4fe1J-3rmtA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ALA A 330
LEU A 303
VAL A 272
LEU A 273
ILE A 322
 None
 0.88A 4g1bA-3rmtA:
undetectable		 4g1bA-3rmtA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		3 / 3 GLY A 215
GLU A 192
THR A 191
 None
 0.55A 4kouA-3rmtA:
undetectable		 4kouA-3rmtA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 VAL A 272
LEU A 273
ILE A 322
ALA A 327
LEU A 326
 None
 1.10A 4o1zB-3rmtA:
undetectable		 4o1zB-3rmtA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 LEU A 104
GLY A 105
LEU A 159
MET A 137
ILE A 220
 None
 1.09A 4ok1A-3rmtA:
undetectable		 4ok1A-3rmtA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.10A 4ptjA-3rmtA:
undetectable		 4ptjA-3rmtA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.08A 4qleA-3rmtA:
undetectable		 4qleA-3rmtA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 11 LEU A 296
PHE A 242
GLY A 268
LEU A 316
LEU A 280
 None
 1.03A 4wnuA-3rmtA:
undetectable		 4wnuA-3rmtA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.10A 4x5fA-3rmtA:
undetectable		 4x5fA-3rmtA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.10A 4x5fB-3rmtA:
undetectable		 4x5fB-3rmtA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.09A 4x5gA-3rmtA:
undetectable		 4x5gA-3rmtA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.09A 4x5hA-3rmtA:
undetectable		 4x5hA-3rmtA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 4 LYS A 174
ASP A  24
GLU A 201
THR A 196
 None
 0.98A 5d4uA-3rmtA:
undetectable		 5d4uA-3rmtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 4 LYS A 174
ASP A  24
GLU A 201
THR A 196
 None
 1.00A 5d4uB-3rmtA:
0.0		 5d4uB-3rmtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 4 LYS A 174
ASP A  24
GLU A 201
THR A 196
 None
 1.05A 5d4uC-3rmtA:
undetectable		 5d4uC-3rmtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 4 LYS A 174
ASP A  24
GLU A 201
THR A 196
 None
 0.97A 5d4uD-3rmtA:
undetectable		 5d4uD-3rmtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.12A 5e8qA-3rmtA:
undetectable		 5e8qA-3rmtA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.12A 5e8qB-3rmtA:
undetectable		 5e8qB-3rmtA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.10A 5eajB-3rmtA:
undetectable		 5eajB-3rmtA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 5 ARG A 392
SER A 239
SER A 238
SER A 419
 None
 1.40A 5hswA-3rmtA:
undetectable		 5hswA-3rmtA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 7 LEU A 149
THR A 131
ILE A 141
LEU A 152
 None
 0.82A 5te8A-3rmtA:
undetectable		 5te8A-3rmtA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		4 / 8 LEU A 149
THR A 131
ILE A 141
LEU A 152
 None
 0.75A 5te8B-3rmtA:
undetectable		 5te8B-3rmtA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.14A 5ujxB-3rmtA:
undetectable		 5ujxB-3rmtA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3rmt 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE 1
(Bacillus
halodurans) 		5 / 12 ILE A  67
LEU A  37
THR A  99
ILE A 103
THR A  42
 None
 1.11A 5z6fA-3rmtA:
undetectable		 5z6fA-3rmtA:
17.80