SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rmv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		5 / 12 LEU A  22
LEU A 108
ALA A 109
MET A 101
LEU A 114
 None
 1.42A 2oaxD-3rmvA:
undetectable		 2oaxD-3rmvA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		5 / 12 LEU A  22
LEU A 108
ALA A 109
MET A 101
LEU A 114
 None
 1.35A 2oaxE-3rmvA:
undetectable		 2oaxE-3rmvA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		5 / 12 ASP A 104
PHE A 213
SER A  25
ILE A 252
PHE A 253
 MN  A 263 ( 1.9A)
None
None
None
None
 1.23A 3clbB-3rmvA:
undetectable		 3clbB-3rmvA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		5 / 12 THR A  32
VAL A  99
LEU A 183
SER A  25
VAL A 136
 None
 1.35A 3frqA-3rmvA:
undetectable		 3frqA-3rmvA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		3 / 3 VAL A  21
SER A  25
LEU A 106
 None
 0.63A 3n8xA-3rmvA:
undetectable		 3n8xA-3rmvA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		4 / 4 LEU A  22
ILE A 111
GLY A  23
PHE A   6
 None
 0.83A 4dc3A-3rmvA:
2.8		 4dc3A-3rmvA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		4 / 4 LEU A  92
LEU A   9
GLN A   4
GLU A 119
 None
UDP  A 264 (-4.1A)
None
None
 1.24A 4i41A-3rmvA:
undetectable		 4i41A-3rmvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		5 / 12 LEU A 152
ALA A 153
LEU A 167
HIS A  88
LEU A  84
 None
 1.19A 4j24D-3rmvA:
undetectable		 4j24D-3rmvA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		3 / 3 LEU A 246
PRO A 243
ARG A 216
 None
 0.61A 4klrB-3rmvA:
undetectable		 4klrB-3rmvA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		4 / 5 PHE A 100
HIS A 212
PHE A 137
PRO A 126
 None
MN  A 263 ( 3.3A)
None
None
 1.30A 4o8zA-3rmvA:
undetectable		 4o8zA-3rmvA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		5 / 12 GLY A  18
LEU A  20
SER A  24
VAL A  54
THR A  53
 None
 1.22A 4wnwA-3rmvA:
undetectable		 4wnwA-3rmvA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		4 / 5 TYR A 224
PHE A 213
LEU A 248
PRO A 219
 None
 1.47A 5csyB-3rmvA:
undetectable		 5csyB-3rmvA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		4 / 6 LYS A 209
SER A 121
VAL A 138
ASP A 113
 None
 1.20A 5hesA-3rmvA:
undetectable		 5hesA-3rmvA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		3 / 3 ASP A 125
ASN A 133
ASP A 102
 None
None
MN  A 263 ( 3.0A)
 0.75A 5vopA-3rmvA:
undetectable		 5vopA-3rmvA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		3 / 3 ASP A 125
ASN A 133
ASP A 102
 None
None
MN  A 263 ( 3.0A)
 0.73A 5vopB-3rmvA:
undetectable		 5vopB-3rmvA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		4 / 7 ASN A 188
HIS A 212
ASP A 163
GLY A 162
 None
MN  A 263 ( 3.3A)
None
None
 1.07A 5x7pA-3rmvA:
undetectable		 5x7pA-3rmvA:
12.01