SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rn2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3rn2 INTERFERON-INDUCIBLE
PROTEIN AIM2
(Homo
sapiens) 		4 / 5 ASP A 283
THR A 274
LEU A 281
GLU A 292
 None
 1.13A 4a3pA-3rn2A:
undetectable		 4a3pA-3rn2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3rn2 INTERFERON-INDUCIBLE
PROTEIN AIM2
(Homo
sapiens) 		4 / 6 ILE A 334
THR A 301
VAL A 264
ASP A 286
 None
 1.13A 4iaqA-3rn2A:
undetectable		 4iaqA-3rn2A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3rn2 INTERFERON-INDUCIBLE
PROTEIN AIM2
(Homo
sapiens) 		5 / 5 ALA A 179
VAL A 158
LYS A 198
PHE A 177
ILE A 207
 None
 1.20A 5of1A-3rn2A:
undetectable		 5of1A-3rn2A:
19.15