SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3rob UNCHARACTERIZED
CONSERVED PROTEIN
(Planctopirus
limnophila) 		4 / 5 ASP A 129
LEU A 126
ALA A 112
LEU A  93
 GOL  A 137 (-2.8A)
None
GOL  A 137 ( 3.7A)
None
 1.13A 1nh8A-3robA:
undetectable		 1nh8A-3robA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 3rob UNCHARACTERIZED
CONSERVED PROTEIN
(Planctopirus
limnophila) 		4 / 8 ARG A  32
LYS A  55
GLU A  56
LEU A  38
 None
 0.73A 2bxgA-3robA:
undetectable		 2bxgA-3robA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3rob UNCHARACTERIZED
CONSERVED PROTEIN
(Planctopirus
limnophila) 		4 / 6 ILE A  95
THR A  47
PHE A  53
PHE A  58
 None
None
None
GOL  A 137 (-4.7A)
 1.30A 3elzB-3robA:
undetectable		 3elzB-3robA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 3rob UNCHARACTERIZED
CONSERVED PROTEIN
(Planctopirus
limnophila) 		4 / 8 THR A  47
PRO A  52
GLY A  54
PHE A  53
 None
 1.05A 3tzfB-3robA:
undetectable		 3tzfB-3robA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 3rob UNCHARACTERIZED
CONSERVED PROTEIN
(Planctopirus
limnophila) 		4 / 6 ALA A 130
ASN A 131
LEU A 132
VAL A 133
 None
GOL  A 137 (-3.4A)
None
None
 0.81A 4g24A-3robA:
undetectable		 4g24A-3robA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 3rob UNCHARACTERIZED
CONSERVED PROTEIN
(Planctopirus
limnophila) 		3 / 3 GLU A  78
ARG A  90
HIS A 111
 None
 0.74A 4kf9A-3robA:
undetectable		 4kf9A-3robA:
17.74