SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rpb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B500_1
(ORF12)		 3rpb RABPHILIN 3-A
(Rattus
norvegicus) 		5 / 9 HIS A 657
VAL A 546
ILE A 627
ARG A 654
GLY A 647
 None
 1.28A 2xf3B-3rpbA:
undetectable		 2xf3B-3rpbA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 3rpb RABPHILIN 3-A
(Rattus
norvegicus) 		5 / 9 HIS A 657
VAL A 546
ILE A 627
ARG A 654
GLY A 647
 None
 1.30A 2xfsB-3rpbA:
undetectable		 2xfsB-3rpbA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 3rpb RABPHILIN 3-A
(Rattus
norvegicus) 		3 / 3 LYS A 543
VAL A 565
HIS A 566
 None
 1.21A 3tj7A-3rpbA:
undetectable		 3tj7A-3rpbA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 3rpb RABPHILIN 3-A
(Rattus
norvegicus) 		4 / 6 THR A 552
GLY A 556
ILE A 558
LEU A 620
 None
 1.22A 4ac9C-3rpbA:
undetectable		 4ac9C-3rpbA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3rpb RABPHILIN 3-A
(Rattus
norvegicus) 		4 / 6 THR A 552
GLY A 556
ILE A 558
LEU A 620
 None
 1.18A 4acaC-3rpbA:
undetectable		 4acaC-3rpbA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 3rpb RABPHILIN 3-A
(Rattus
norvegicus) 		4 / 6 ASP A 577
ASN A 573
ALA A 572
ASP A 631
 None
 1.16A 4mdaA-3rpbA:
undetectable		 4mdaA-3rpbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 3rpb RABPHILIN 3-A
(Rattus
norvegicus) 		4 / 6 ASP A 633
ASP A 571
ASN A 573
ASP A 631
 None
 1.07A 4mdaA-3rpbA:
undetectable		 4mdaA-3rpbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 3rpb RABPHILIN 3-A
(Rattus
norvegicus) 		4 / 6 ASP A 577
ASN A 573
ALA A 572
ASP A 631
 None
 1.15A 4mdbA-3rpbA:
undetectable		 4mdbA-3rpbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 3rpb RABPHILIN 3-A
(Rattus
norvegicus) 		5 / 12 GLY A 642
VAL A 629
PHE A 607
PRO A 605
THR A 602
 None
 1.18A 6brdC-3rpbA:
undetectable		 6brdC-3rpbA:
17.81