SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rpc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 8 ASP A  73
HIS A  74
ILE A 201
HIS A 223
 ZN  A 302 (-2.8A)
ZN  A 302 (-3.4A)
None
ZN  A 302 (-3.5A)
 0.79A 1ei6C-3rpcA:
undetectable		 1ei6C-3rpcA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 6 PHE A  26
PHE A  36
HIS A 229
ASN A 228
 None
 1.34A 1tt0A-3rpcA:
undetectable		 1tt0A-3rpcA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 6 PHE A  26
PHE A  36
HIS A 229
ASN A 228
 None
 1.32A 1tt0B-3rpcA:
undetectable		 1tt0B-3rpcA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 6 PHE A  26
PHE A  36
HIS A 229
ASN A 228
 None
 1.37A 1tt0C-3rpcA:
undetectable		 1tt0C-3rpcA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 6 PHE A  26
PHE A  36
HIS A 229
ASN A 228
 None
 1.35A 1tt0D-3rpcA:
undetectable		 1tt0D-3rpcA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 12 THR A  68
THR A 125
GLY A 164
GLY A 127
VAL A 222
 None
 1.15A 2b25B-3rpcA:
undetectable		 2b25B-3rpcA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 8 LEU A 162
ASN A   9
HIS A  74
HIS A 223
 None
None
ZN  A 302 (-3.4A)
ZN  A 302 (-3.5A)
 0.96A 2bnnA-3rpcA:
undetectable
2bnnB-3rpcA:
undetectable		 2bnnA-3rpcA:
23.44
2bnnB-3rpcA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 ASP A  73
HIS A  74
HIS A 129
ASP A 165
HIS A 223
 ZN  A 302 (-2.8A)
ZN  A 302 (-3.4A)
ZN  A 301 (-3.3A)
ZN  A 302 ( 2.5A)
ZN  A 302 (-3.5A)
 0.56A 2q0jB-3rpcA:
8.6		 2q0jB-3rpcA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB926_0
(FERROCHELATASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 10 MET A  55
LEU A  59
ILE A  83
PRO A  52
GLY A  12
 None
 1.28A 2qd4B-3rpcA:
undetectable		 2qd4B-3rpcA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.38A 2zweA-3rpcA:
undetectable
2zweB-3rpcA:
undetectable		 2zweA-3rpcA:
24.43
2zweB-3rpcA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.36A 2zwfA-3rpcA:
undetectable
2zwfB-3rpcA:
undetectable		 2zwfA-3rpcA:
24.43
2zwfB-3rpcA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.40A 2zwgA-3rpcA:
undetectable
2zwgB-3rpcA:
undetectable		 2zwgA-3rpcA:
24.43
2zwgB-3rpcA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 5 ASN A  41
ASN A   9
HIS A 223
ALA A 191
 None
None
ZN  A 302 (-3.5A)
None
 1.33A 3frqA-3rpcA:
undetectable		 3frqA-3rpcA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 7 ASN A  41
ASN A   9
HIS A 223
ALA A 191
 None
None
ZN  A 302 (-3.5A)
None
 1.34A 3frqB-3rpcA:
undetectable		 3frqB-3rpcA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 10 MET A  55
LEU A  59
ILE A  83
PRO A  52
GLY A  12
 None
 1.37A 3hcpB-3rpcA:
undetectable		 3hcpB-3rpcA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 6 PHE A  26
PHE A  36
HIS A 229
ASN A 228
 None
 1.37A 3lskB-3rpcA:
undetectable		 3lskB-3rpcA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 6 PHE A  26
PHE A  36
HIS A 229
ASN A 228
 None
 1.36A 3lskD-3rpcA:
undetectable		 3lskD-3rpcA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 6 ALA A 191
ILE A 201
HIS A 129
HIS A  74
 None
None
ZN  A 301 (-3.3A)
ZN  A 302 (-3.4A)
 1.05A 3nneG-3rpcA:
undetectable		 3nneG-3rpcA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 7 ASP A  73
HIS A  74
ILE A 201
HIS A 223
 ZN  A 302 (-2.8A)
ZN  A 302 (-3.4A)
None
ZN  A 302 (-3.5A)
 0.81A 3t01A-3rpcA:
undetectable		 3t01A-3rpcA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 6 THR A   5
ARG A 234
ILE A 220
LEU A  14
 None
 0.85A 4acbC-3rpcA:
3.2		 4acbC-3rpcA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 10 HIS A  69
HIS A  71
ASP A  73
HIS A 129
HIS A 223
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
ZN  A 302 (-2.8A)
ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
 0.88A 4c1dB-3rpcA:
6.8		 4c1dB-3rpcA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A  69
HIS A  71
ASP A  73
HIS A 129
HIS A 223
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
ZN  A 302 (-2.8A)
ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
 0.92A 4c1fA-3rpcA:
7.3
4c1fB-3rpcA:
7.8		 4c1fA-3rpcA:
21.24
4c1fB-3rpcA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 9 HIS A  69
HIS A  71
ASP A  73
HIS A 129
HIS A 223
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
ZN  A 302 (-2.8A)
ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
 0.88A 4c1hA-3rpcA:
8.1		 4c1hA-3rpcA:
27.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_A_X8ZA301_1
(BETA-LACTAMASE NDM-1)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 9 MET A  46
VAL A 227
HIS A  71
HIS A 129
HIS A 223
 None
None
ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
 1.34A 4exsA-3rpcA:
7.0		 4exsA-3rpcA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 8 HIS A  71
ASP A  73
HIS A 129
HIS A 223
 ZN  A 301 (-3.4A)
ZN  A 302 (-2.8A)
ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
 0.91A 4exsB-3rpcA:
7.3		 4exsB-3rpcA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 6 HIS A 129
ILE A 200
PHE A  36
ASN A 228
 ZN  A 301 (-3.3A)
None
None
None
 1.48A 4o7gB-3rpcA:
undetectable		 4o7gB-3rpcA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 8 HIS A  71
ASP A  73
HIS A 129
HIS A 223
 ZN  A 301 (-3.4A)
ZN  A 302 (-2.8A)
ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
 0.89A 5a5zA-3rpcA:
7.1		 5a5zA-3rpcA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		6 / 11 HIS A  69
HIS A  71
ASP A  73
HIS A  74
HIS A 129
HIS A 223
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
ZN  A 302 (-2.8A)
ZN  A 302 (-3.4A)
ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
 0.45A 5ayaA-3rpcA:
8.7		 5ayaA-3rpcA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 12 MET A 186
ILE A 219
VAL A 163
ALA A 175
VAL A 172
 None
 1.10A 5igiA-3rpcA:
undetectable		 5igiA-3rpcA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 8 ASP A 165
HIS A  74
HIS A 223
HIS A 129
 ZN  A 302 ( 2.5A)
ZN  A 302 (-3.4A)
ZN  A 302 (-3.5A)
ZN  A 301 (-3.3A)
 0.99A 5nekB-3rpcA:
undetectable		 5nekB-3rpcA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 8 ASP A 165
HIS A  74
HIS A 223
HIS A 129
 ZN  A 302 ( 2.5A)
ZN  A 302 (-3.4A)
ZN  A 302 (-3.5A)
ZN  A 301 (-3.3A)
 0.88A 5nekD-3rpcA:
undetectable		 5nekD-3rpcA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 8 ASP A 165
HIS A 129
HIS A  69
HIS A 223
 ZN  A 302 ( 2.5A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
ZN  A 302 (-3.5A)
 0.91A 5nekD-3rpcA:
undetectable		 5nekD-3rpcA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 10 HIS A  69
HIS A  71
HIS A  74
HIS A 129
ASP A 165
 ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
ZN  A 302 (-3.4A)
ZN  A 301 (-3.3A)
ZN  A 302 ( 2.5A)
 0.52A 5nzwA-3rpcA:
12.4		 5nzwA-3rpcA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 10 HIS A  74
HIS A 223
HIS A  69
ASP A 165
HIS A 129
 ZN  A 302 (-3.4A)
ZN  A 302 (-3.5A)
ZN  A 301 (-3.4A)
ZN  A 302 ( 2.5A)
ZN  A 301 (-3.3A)
 1.05A 5nzwA-3rpcA:
12.4		 5nzwA-3rpcA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.43A 5z0fA-3rpcA:
undetectable
5z0fB-3rpcA:
undetectable		 5z0fA-3rpcA:
13.30
5z0fB-3rpcA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.40A 5z0gA-3rpcA:
undetectable
5z0gB-3rpcA:
undetectable		 5z0gA-3rpcA:
13.30
5z0gB-3rpcA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.40A 5z0hA-3rpcA:
undetectable
5z0hB-3rpcA:
undetectable		 5z0hA-3rpcA:
13.30
5z0hB-3rpcA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.40A 5z0iA-3rpcA:
undetectable
5z0iB-3rpcA:
undetectable		 5z0iA-3rpcA:
13.30
5z0iB-3rpcA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.39A 5z0jA-3rpcA:
undetectable
5z0jB-3rpcA:
undetectable		 5z0jA-3rpcA:
13.30
5z0jB-3rpcA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.31A 5z0kA-3rpcA:
undetectable
5z0kB-3rpcA:
undetectable		 5z0kA-3rpcA:
13.30
5z0kB-3rpcA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		5 / 11 HIS A 129
HIS A 223
ASN A   9
HIS A  74
PRO A  47
 ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
None
ZN  A 302 (-3.4A)
None
 1.35A 5z0lA-3rpcA:
undetectable
5z0lB-3rpcA:
undetectable		 5z0lA-3rpcA:
13.30
5z0lB-3rpcA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 8 HIS A  71
ASP A  73
HIS A 129
HIS A 223
 ZN  A 301 (-3.4A)
ZN  A 302 (-2.8A)
ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
 0.98A 5zj8A-3rpcA:
7.2		 5zj8A-3rpcA:
25.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 8 MET A  46
HIS A  71
HIS A 129
HIS A 223
 None
ZN  A 301 (-3.4A)
ZN  A 301 (-3.3A)
ZN  A 302 (-3.5A)
 1.04A 5zj8A-3rpcA:
7.2		 5zj8A-3rpcA:
25.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3rpc POSSIBLE
METAL-DEPENDENT
HYDROLASE
(Veillonella
parvula) 		4 / 5 PHE A  26
ASP A  73
HIS A  74
THR A 226
 None
ZN  A 302 (-2.8A)
ZN  A 302 (-3.4A)
None
 1.11A 6b58A-3rpcA:
undetectable		 6b58A-3rpcA:
18.72