SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rpf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3rpf MOLYBDOPTERIN
SYNTHASE CATALYTIC
SUBUNIT
(Helicobacter
pylori) 		4 / 5 ARG A 134
ASP A 122
ILE A 124
GLU A 133
 None
 1.13A 2xrzA-3rpfA:
undetectable
2xrzB-3rpfA:
undetectable		 2xrzA-3rpfA:
15.07
2xrzB-3rpfA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3rpf MOLYBDOPTERIN
SYNTHASE CATALYTIC
SUBUNIT
(Helicobacter
pylori) 		3 / 3 ASP A 111
PHE A 108
LEU A 104
 None
 0.73A 2zi9A-3rpfA:
undetectable		 2zi9A-3rpfA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VFJ_A_ACTA410_0
(MALTOSE-BINDING
PERIPLASMIC PROTEIN,
C-TERMINAL FUSED BY
CYS-LYS-D-ALA-D-ALA)		 3rpf MOLYBDOPTERIN
SYNTHASE CATALYTIC
SUBUNIT
(Helicobacter
pylori) 		4 / 4 LYS A   3
ALA A  17
GLU A  13
LEU A  14
 None
 1.35A 3vfjA-3rpfA:
undetectable		 3vfjA-3rpfA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3rpf MOLYBDOPTERIN
SYNTHASE CATALYTIC
SUBUNIT
(Helicobacter
pylori) 		4 / 8 THR A  11
LEU A  15
VAL A  32
VAL A  34
 None
 0.95A 4em2A-3rpfA:
undetectable		 4em2A-3rpfA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3rpf MOLYBDOPTERIN
CONVERTING FACTOR,
SUBUNIT 1 (MOAD)
(Helicobacter
pylori) 		4 / 7 PHE C  16
ILE C  18
PHE C   7
LEU C  40
 None
 0.98A 5esmA-3rpfC:
undetectable		 5esmA-3rpfC:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3rpf MOLYBDOPTERIN
SYNTHASE CATALYTIC
SUBUNIT
(Helicobacter
pylori) 		4 / 4 VAL A  92
VAL A  32
TYR A  18
GLN A  19
 None
 1.30A 5qgoA-3rpfA:
undetectable		 5qgoA-3rpfA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3rpf MOLYBDOPTERIN
SYNTHASE CATALYTIC
SUBUNIT
(Helicobacter
pylori) 		4 / 4 VAL A  92
VAL A  32
TYR A  18
GLN A  19
 None
 1.27A 5qgpA-3rpfA:
undetectable		 5qgpA-3rpfA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3rpf MOLYBDOPTERIN
SYNTHASE CATALYTIC
SUBUNIT
(Helicobacter
pylori) 		4 / 4 VAL A  92
VAL A  32
TYR A  18
GLN A  19
 None
 1.28A 5qgqA-3rpfA:
undetectable		 5qgqA-3rpfA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3rpf MOLYBDOPTERIN
SYNTHASE CATALYTIC
SUBUNIT
(Helicobacter
pylori) 		4 / 4 VAL A  92
VAL A  32
TYR A  18
GLN A  19
 None
 1.29A 5qhbA-3rpfA:
undetectable		 5qhbA-3rpfA:
21.81