SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rpx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB500_0 (ILEAL BILE ACID-BINDING PROTEIN)	3rpx	COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN (Homo sapiens)	4 / 7	LYS A 119 THR A 130 VAL A 169 VAL A 183	None	0.57A	3em0B-3rpxA: undetectable	3em0B-3rpxA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_A_TLFA300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	3rpx	COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN (Homo sapiens)	5 / 12	VAL A 183 PHE A 204 TRP A 109 VAL A 169 PHE A 168	None UNX A 60 ( 4.7A) None None None	1.03A	6ap6A-3rpxA: undetectable	6ap6A-3rpxA: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_B_TLFB300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	3rpx	COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN (Homo sapiens)	5 / 12	VAL A 183 PHE A 204 TRP A 109 VAL A 169 PHE A 168	None UNX A 60 ( 4.7A) None None None	1.05A	6ap6B-3rpxA: undetectable	6ap6B-3rpxA: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_G_TA1G501_2 (TUBULIN BETA CHAIN)	3rpx	COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN (Homo sapiens)	4 / 6	LEU A 111 LEU A 256 THR A 130 ARG A 207	None	1.09A	6ew0G-3rpxA: undetectable	6ew0G-3rpxA: 19.55

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3EM0_B_CHDB500_0","ILEAL BILE ACID-BINDING PROTEIN","3rpx","COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN","Homo sapiens",4,"LYS A 119;THR A 130;VAL A 169;VAL A 183","None","0.57A","3em0B-3rpxA:undetectable","3em0B-3rpxA:20.20"],["6AP6_A_TLFA300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","3rpx","COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN","Homo sapiens",5,"VAL A 183;PHE A 204;TRP A 109;VAL A 169;PHE A 168","None;UNX A  60 ( 4.7A);None;None;None","1.03A","6ap6A-3rpxA:undetectable","6ap6A-3rpxA:20.34"],["6AP6_B_TLFB300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","3rpx","COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN","Homo sapiens",5,"VAL A 183;PHE A 204;TRP A 109;VAL A 169;PHE A 168","None;UNX A  60 ( 4.7A);None;None;None","1.05A","6ap6B-3rpxA:undetectable","6ap6B-3rpxA:20.34"],["6EW0_G_TA1G501_2","TUBULIN BETA CHAIN","3rpx","COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN","Homo sapiens",4,"LEU A 111;LEU A 256;THR A 130;ARG A 207","None","1.09A","6ew0G-3rpxA:undetectable","6ew0G-3rpxA:19.55"]]