SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 5 PRO A 191
VAL A 193
VAL A 201
ILE A 203
 None
 1.01A 1z2bC-3rqbA:
undetectable		 1z2bC-3rqbA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 6 LEU A 141
SER A 155
PHE A 157
ASP A 158
 None
 1.29A 2vn1B-3rqbA:
undetectable		 2vn1B-3rqbA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 PHE A 109
PHE A 212
ALA A 183
ALA A  43
THR A  13
 None
 1.30A 2x2nA-3rqbA:
undetectable		 2x2nA-3rqbA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 PHE A 109
PHE A 212
ALA A 183
ALA A  43
THR A  13
 None
 1.32A 2x2nC-3rqbA:
undetectable		 2x2nC-3rqbA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 PHE A 109
PHE A 212
ALA A 183
ALA A  43
THR A  13
 None
 1.31A 2x2nD-3rqbA:
undetectable		 2x2nD-3rqbA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 5 HIS A 118
ARG A 221
ASP A 253
THR A 119
 None
 1.44A 3okxA-3rqbA:
0.0		 3okxA-3rqbA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_2
(YAEB-LIKE PROTEIN
RPA0152)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 5 HIS A 118
ARG A 221
ASP A 253
THR A 119
 None
 1.48A 3okxB-3rqbA:
undetectable		 3okxB-3rqbA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 8 LEU A  46
VAL A  64
VAL A 210
LEU A  93
 None
 1.01A 4q0bA-3rqbA:
undetectable		 4q0bA-3rqbA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 LEU A  62
LEU A  46
ALA A  48
ALA A  49
 None
 0.80A 6a7jA-3rqbA:
undetectable		 6a7jA-3rqbA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3rqb UNCHARACTERIZED
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 6 MET A 169
ARG A 175
ALA A 181
LEU A 177
 None
 0.94A 6fosB-3rqbA:
undetectable		 6fosB-3rqbA:
14.02