SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HXY_B_ACAB502_1 (PLM1)	3rqi	RESPONSE REGULATOR PROTEIN (Burkholderia pseudomallei)	4 / 7	VAL A 80 SER A 86 TYR A 101 LEU A 63	None SO4 A 184 (-4.9A) None None	1.11A	4hxyB-3rqiA: 4.8	4hxyB-3rqiA: 19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LBG_B_ADNB402_1 (PROBABLE SUGAR KINASE PROTEIN)	3rqi	RESPONSE REGULATOR PROTEIN (Burkholderia pseudomallei)	5 / 9	ALA A 43 ILE A 51 VAL A 53 ALA A 33 ILE A 9	None None PHD A 54 ( 3.1A) None None	1.01A	4lbgB-3rqiA: 5.4	4lbgB-3rqiA: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP6_A_B40A601_1 (TRANSPORTER)	3rqi	RESPONSE REGULATOR PROTEIN (Burkholderia pseudomallei)	4 / 5	ASP A 11 VAL A 8 PHE A 15 GLY A 17	CIT A 182 ( 2.5A) None None None	1.26A	4xp6A-3rqiA: undetectable	4xp6A-3rqiA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5Z_D_9CRD501_0 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3rqi	RESPONSE REGULATOR PROTEIN (Burkholderia pseudomallei)	5 / 12	ALA A 33 GLN A 32 ILE A 51 ALA A 16 ILE A 66	None	0.96A	6a5zD-3rqiA: undetectable	6a5zD-3rqiA: 22.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4HXY_B_ACAB502_1","PLM1","3rqi","RESPONSE REGULATOR PROTEIN","Burkholderia pseudomallei",4,"VAL A  80;SER A  86;TYR A 101;LEU A  63","None;SO4 A 184 (-4.9A);None;None","1.11A","4hxyB-3rqiA:4.8","4hxyB-3rqiA:19.18"],["4LBG_B_ADNB402_1","PROBABLE SUGAR KINASE PROTEIN","3rqi","RESPONSE REGULATOR PROTEIN","Burkholderia pseudomallei",5,"ALA A  43;ILE A  51;VAL A  53;ALA A  33;ILE A   9","None;None;PHD A  54 ( 3.1A);None;None","1.01A","4lbgB-3rqiA:5.4","4lbgB-3rqiA:22.60"],["4XP6_A_B40A601_1","TRANSPORTER","3rqi","RESPONSE REGULATOR PROTEIN","Burkholderia pseudomallei",4,"ASP A  11;VAL A   8;PHE A  15;GLY A  17","CIT A 182 ( 2.5A);None;None;None","1.26A","4xp6A-3rqiA:undetectable","4xp6A-3rqiA:17.05"],["6A5Z_D_9CRD501_0","RETINOIC ACID RECEPTOR RXR-ALPHA","3rqi","RESPONSE REGULATOR PROTEIN","Burkholderia pseudomallei",5,"ALA A  33;GLN A  32;ILE A  51;ALA A  16;ILE A  66","None","0.96A","6a5zD-3rqiA:undetectable","6a5zD-3rqiA:22.70"]]