SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rr5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 12 ILE A 277
LEU A 300
LEU A 347
ILE A 382
PHE A 350
 None
 0.92A 1fmlB-3rr5A:
undetectable		 1fmlB-3rr5A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		3 / 3 GLU A 397
LYS A 392
VAL A 393
 None
 0.89A 1l2iA-3rr5A:
undetectable		 1l2iA-3rr5A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 8 LYS A 133
VAL A 134
TYR A 149
LEU A 150
 None
 0.95A 1z2bB-3rr5A:
undetectable		 1z2bB-3rr5A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 VAL A 213
ARG A 199
VAL A 192
GLU A 217
 None
 1.08A 1zzrA-3rr5A:
undetectable
1zzrB-3rr5A:
undetectable		 1zzrA-3rr5A:
21.40
1zzrB-3rr5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.05A 1zzrA-3rr5A:
undetectable
1zzrB-3rr5A:
undetectable		 1zzrA-3rr5A:
21.40
1zzrB-3rr5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.08A 1zzuA-3rr5A:
undetectable
1zzuB-3rr5A:
undetectable		 1zzuA-3rr5A:
21.40
1zzuB-3rr5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 12 GLY A 309
TYR A 278
ALA A 385
TYR A 261
ARG A 280
 None
None
None
None
MG  A 601 ( 4.4A)
 1.35A 2avdB-3rr5A:
undetectable		 2avdB-3rr5A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 4 ALA A 211
VAL A 197
PHE A 207
THR A 204
 None
 1.05A 2pkkA-3rr5A:
undetectable		 2pkkA-3rr5A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		3 / 3 LEU A 406
VAL A 314
ARG A 319
 None
 0.88A 3b0wB-3rr5A:
undetectable		 3b0wB-3rr5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 8 ALA A 211
PHE A 190
LEU A 182
ALA A 189
 None
 0.89A 3hrdA-3rr5A:
undetectable
3hrdB-3rr5A:
undetectable		 3hrdA-3rr5A:
22.13
3hrdB-3rr5A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.07A 3jx2A-3rr5A:
undetectable
3jx2B-3rr5A:
undetectable		 3jx2A-3rr5A:
20.64
3jx2B-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 VAL A 213
ARG A 199
VAL A 192
GLU A 217
 None
 1.07A 3jx3A-3rr5A:
undetectable
3jx3B-3rr5A:
undetectable		 3jx3A-3rr5A:
20.64
3jx3B-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.06A 3jx3A-3rr5A:
undetectable
3jx3B-3rr5A:
undetectable		 3jx3A-3rr5A:
20.64
3jx3B-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.07A 3jx4A-3rr5A:
undetectable
3jx4B-3rr5A:
undetectable		 3jx4A-3rr5A:
20.64
3jx4B-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 VAL A 213
ARG A 199
VAL A 192
GLU A 217
 None
 1.04A 3jx5A-3rr5A:
undetectable
3jx5B-3rr5A:
undetectable		 3jx5A-3rr5A:
20.64
3jx5B-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.08A 3jx5A-3rr5A:
undetectable
3jx5B-3rr5A:
undetectable		 3jx5A-3rr5A:
20.64
3jx5B-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 VAL A 213
ARG A 199
VAL A 192
GLU A 217
 None
 1.05A 3nlpA-3rr5A:
undetectable
3nlpB-3rr5A:
undetectable		 3nlpA-3rr5A:
20.64
3nlpB-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.08A 3nlpA-3rr5A:
undetectable
3nlpB-3rr5A:
undetectable		 3nlpA-3rr5A:
20.64
3nlpB-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 8 VAL A 213
ARG A 199
VAL A 192
GLU A 217
 None
 1.03A 3nlqA-3rr5A:
undetectable
3nlqB-3rr5A:
undetectable		 3nlqA-3rr5A:
20.64
3nlqB-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 VAL A 213
ARG A 199
VAL A 192
GLU A 217
 None
 1.06A 3nlrA-3rr5A:
undetectable
3nlrB-3rr5A:
undetectable		 3nlrA-3rr5A:
20.64
3nlrB-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_A_ADNA501_1
(DNA LIGASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		6 / 12 GLU A 258
LYS A 260
GLU A 310
PHE A 350
LYS A 414
LYS A 431
 None
MG  A 601 ( 4.8A)
None
None
None
None
 0.76A 3qwuA-3rr5A:
10.6		 3qwuA-3rr5A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_B_ADNB501_1
(DNA LIGASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 11 GLU A 258
LYS A 260
GLU A 310
PHE A 350
LYS A 414
 None
MG  A 601 ( 4.8A)
None
None
None
 0.73A 3qwuB-3rr5A:
5.7		 3qwuB-3rr5A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		3 / 3 LYS A 301
PRO A 302
LEU A 300
 None
 0.83A 3tpxE-3rr5A:
undetectable		 3tpxE-3rr5A:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 12 LEU A 300
LYS A 383
LEU A 349
ASN A 348
ILE A 277
 None
 1.16A 3ut5B-3rr5A:
undetectable		 3ut5B-3rr5A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		3 / 3 LYS A 431
ARG A 281
LEU A 237
 None
 1.38A 3v4tE-3rr5A:
undetectable		 3v4tE-3rr5A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 10 GLY A 309
LEU A 353
LEU A 349
ASN A 348
ILE A 352
 None
 0.99A 3wdmB-3rr5A:
undetectable		 3wdmB-3rr5A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 9 GLY A 309
LEU A 353
LEU A 349
ASN A 348
ILE A 352
 None
 1.06A 3wdmC-3rr5A:
undetectable		 3wdmC-3rr5A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 10 GLY A 309
LEU A 353
LEU A 349
ASN A 348
ILE A 352
 None
 1.08A 3wdmD-3rr5A:
undetectable		 3wdmD-3rr5A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.09A 4cx3A-3rr5A:
undetectable
4cx3B-3rr5A:
undetectable		 4cx3A-3rr5A:
20.64
4cx3B-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 VAL A 213
ARG A 199
VAL A 192
GLU A 217
 None
 1.09A 4cx4A-3rr5A:
undetectable
4cx4B-3rr5A:
undetectable		 4cx4A-3rr5A:
20.64
4cx4B-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.09A 4cx4A-3rr5A:
undetectable
4cx4B-3rr5A:
undetectable		 4cx4A-3rr5A:
20.64
4cx4B-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 12 ALA A 464
ASP A 551
ILE A 556
GLY A 476
ILE A 553
 None
 0.87A 4q1xB-3rr5A:
undetectable		 4q1xB-3rr5A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 6 LEU A  55
ILE A  56
LEU A  17
TYR A  14
 None
 0.89A 4w5nA-3rr5A:
undetectable		 4w5nA-3rr5A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 4 GLY A 180
LEU A  41
PHE A  40
ILE A  56
 None
 0.93A 4xv2A-3rr5A:
undetectable		 4xv2A-3rr5A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 12 LEU A 347
ILE A 292
ILE A 289
VAL A 307
LEU A 300
 None
 1.11A 4y0pA-3rr5A:
undetectable		 4y0pA-3rr5A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.03A 5addA-3rr5A:
undetectable
5addB-3rr5A:
undetectable		 5addA-3rr5A:
20.64
5addB-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.00A 5adeA-3rr5A:
undetectable
5adeB-3rr5A:
undetectable		 5adeA-3rr5A:
20.64
5adeB-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 5 ILE A 443
GLY A 476
ILE A 514
LEU A 461
 None
 0.88A 5dzki-3rr5A:
undetectable
5dzkj-3rr5A:
undetectable
5dzkx-3rr5A:
undetectable		 5dzki-3rr5A:
16.31
5dzkj-3rr5A:
16.31
5dzkx-3rr5A:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 VAL A 213
ARG A 199
VAL A 192
GLU A 217
 None
 1.07A 5g0pA-3rr5A:
undetectable
5g0pB-3rr5A:
undetectable		 5g0pA-3rr5A:
20.64
5g0pB-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 7 GLU A 217
VAL A 213
ARG A 199
VAL A 192
 None
 1.09A 5g0pA-3rr5A:
undetectable
5g0pB-3rr5A:
undetectable		 5g0pA-3rr5A:
20.64
5g0pB-3rr5A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		5 / 12 ILE A 382
LEU A 311
THR A 286
ALA A 313
VAL A 314
 None
 1.06A 5x66F-3rr5A:
undetectable		 5x66F-3rr5A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		3 / 3 LYS A 383
SER A 299
SER A 379
 None
 0.96A 6gbfA-3rr5A:
undetectable		 6gbfA-3rr5A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 3rr5 DNA LIGASE
(Thermococcus
sp.
1519) 		4 / 8 ALA A 214
GLY A 221
LEU A 222
ALA A 200
 None
 0.81A 6mdqA-3rr5A:
undetectable		 6mdqA-3rr5A:
9.84