SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rr6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		3 / 3 ALA A 208
VAL A 213
TRP A 212
 PEG  A 274 (-3.8A)
None
None
 0.91A 1bdwA-3rr6A:
undetectable
1bdwB-3rr6A:
undetectable		 1bdwA-3rr6A:
5.94
1bdwB-3rr6A:
5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		3 / 3 ALA A 215
VAL A 213
TRP A 212
 None
 0.92A 1bdwA-3rr6A:
undetectable
1bdwB-3rr6A:
undetectable		 1bdwA-3rr6A:
5.94
1bdwB-3rr6A:
5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		4 / 7 LEU A 178
GLY A 139
LEU A   3
LYS A   1
 None
 0.96A 1gtiD-3rr6A:
undetectable		 1gtiD-3rr6A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		4 / 7 LEU A 178
GLY A 139
LEU A   3
LYS A   1
 None
 0.96A 1gtiE-3rr6A:
undetectable		 1gtiE-3rr6A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 GLY A  97
ALA A  56
ILE A 174
ILE A 142
VAL A  63
 None
 0.90A 1muiB-3rr6A:
undetectable		 1muiB-3rr6A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		3 / 3 TRP A 212
VAL A  86
PRO A  85
 None
None
EDO  A 268 (-4.8A)
 0.97A 1rg1A-3rr6A:
undetectable		 1rg1A-3rr6A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		3 / 3 TRP A 212
VAL A  86
PRO A  85
 None
None
EDO  A 268 (-4.8A)
 0.97A 1rh0A-3rr6A:
undetectable		 1rh0A-3rr6A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		4 / 8 ASP A 145
LYS A 162
GLY A 228
GLU A 116
 None
UNX  A 271 ( 3.2A)
None
None
 0.94A 2ys6A-3rr6A:
undetectable		 2ys6A-3rr6A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		5 / 10 LEU A 178
VAL A 120
ILE A  58
GLY A   4
ILE A  17
 None
None
EDO  A 276 (-4.2A)
None
None
 1.08A 3el5A-3rr6A:
undetectable		 3el5A-3rr6A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		3 / 3 HIS A 113
SER A 253
ASN A 190
 None
None
PEG  A 266 (-3.9A)
 0.85A 3s8pB-3rr6A:
undetectable		 3s8pB-3rr6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		4 / 5 LEU A 202
ALA A 208
MET A  66
THR A 227
 None
PEG  A 274 (-3.8A)
None
None
 1.25A 3vasB-3rr6A:
undetectable		 3vasB-3rr6A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		3 / 3 GLU A 188
GLY A 191
SER A 243
 EDO  A 270 ( 4.9A)
None
None
 0.39A 4b53B-3rr6A:
2.3		 4b53B-3rr6A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		4 / 5 PRO A 169
ASN A 144
ILE A 236
VAL A 233
 None
 1.34A 4hytA-3rr6A:
undetectable		 4hytA-3rr6A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		3 / 3 HIS A 113
SER A 253
ASN A 190
 None
None
PEG  A 266 (-3.9A)
 0.81A 5cprB-3rr6A:
undetectable		 5cprB-3rr6A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		4 / 5 ARG A 160
HIS A 164
ALA A 148
ASP A 150
 EDO  A 265 (-4.0A)
EDO  A 265 (-4.8A)
None
None
 1.35A 5mfxA-3rr6A:
undetectable		 5mfxA-3rr6A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacteroides
abscessus) 		4 / 5 LEU A   3
THR A 176
THR A 141
GLY A 139
 None
 1.21A 6gtqA-3rr6A:
undetectable		 6gtqA-3rr6A:
21.07