SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rrc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		4 / 6 ARG A 394
ILE A 471
GLY A 470
ALA A 469
 None
 1.00A 1wrqB-3rrcA:
undetectable		 1wrqB-3rrcA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		3 / 3 GLU A 464
GLN A 388
ARG A 391
 None
 0.70A 2w3bB-3rrcA:
undetectable		 2w3bB-3rrcA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		6 / 12 ASP A 309
ILE A 313
GLY A 321
ILE A 322
THR A 251
VAL A 213
 None
None
EDO  A   3 ( 3.1A)
None
None
None
 1.40A 3d1xA-3rrcA:
undetectable		 3d1xA-3rrcA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		6 / 12 ASP A 309
ILE A 313
GLY A 321
ILE A 322
THR A 251
VAL A 213
 None
None
EDO  A   3 ( 3.1A)
None
None
None
 1.45A 3d1yA-3rrcA:
undetectable		 3d1yA-3rrcA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		4 / 8 ASP A 309
GLY A 321
ILE A 322
THR A 251
 None
EDO  A   3 ( 3.1A)
None
None
 0.82A 3el9A-3rrcA:
undetectable		 3el9A-3rrcA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		3 / 3 ARG A 226
ILE A 322
THR A 251
 None
 0.74A 3ia4D-3rrcA:
undetectable		 3ia4D-3rrcA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		4 / 5 LEU A 379
ALA A 382
MET A 362
THR A 359
 None
 1.39A 3vasB-3rrcA:
undetectable		 3vasB-3rrcA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		4 / 7 ASP A 318
GLN A 388
PRO A 387
ASP A 235
 EDO  A   3 (-4.6A)
None
None
None
 1.08A 4pcuA-3rrcA:
undetectable		 4pcuA-3rrcA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		6 / 12 ASP A 309
ILE A 313
GLY A 321
ILE A 322
THR A 251
VAL A 213
 None
None
EDO  A   3 ( 3.1A)
None
None
None
 1.44A 5kqxA-3rrcA:
undetectable		 5kqxA-3rrcA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		5 / 9 ASP A 309
ILE A 313
GLY A 321
ILE A 322
THR A 251
 None
None
EDO  A   3 ( 3.1A)
None
None
 1.27A 5kr2A-3rrcA:
undetectable		 5kr2A-3rrcA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		5 / 9 ASP A 309
ILE A 313
GLY A 321
ILE A 322
THR A 251
 None
None
EDO  A   3 ( 3.1A)
None
None
 1.30A 5kr2C-3rrcA:
undetectable		 5kr2C-3rrcA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		4 / 5 LEU A 272
ARG A 346
LEU A 250
TRP A 349
 None
EDO  A   3 ( 4.9A)
None
None
 1.05A 5m10A-3rrcA:
1.2		 5m10A-3rrcA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3rrc DUFFY RECEPTOR
(Plasmodium
vivax) 		4 / 6 ARG A 224
GLU A 403
ASP A 399
GLU A 395
 None
 1.18A 6mn5D-3rrcA:
undetectable		 6mn5D-3rrcA:
13.64