SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_A_VIAA901_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	3rri	GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE (Alicyclobacillus acidocaldarius)	5 / 11	ALA A 85 ILE A 90 PHE A 44 LEU A 49 PHE A 23	None	1.12A	2h42A-3rriA: undetectable	2h42A-3rriA: 17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6E43_B_BEZB502_0 (INDOLEAMINE 2,3-DIOXYGENASE 1)	3rri	GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE (Alicyclobacillus acidocaldarius)	4 / 6	PHE A 72 LEU A 84 LEU A 81 HIS A 77	None	0.88A	6e43B-3rriA: undetectable	6e43B-3rriA: 15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6E43_D_BEZD502_0 (INDOLEAMINE 2,3-DIOXYGENASE 1)	3rri	GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE (Alicyclobacillus acidocaldarius)	4 / 6	PHE A 72 LEU A 84 LEU A 81 HIS A 77	None	0.95A	6e43D-3rriA: undetectable	6e43D-3rriA: 15.14