SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rrl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Helicobacter
pylori) 		4 / 4 ILE A   5
LEU A 165
VAL A 189
ILE A 192
 None
 0.93A 1fm6D-3rrlA:
undetectable		 1fm6D-3rrlA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Helicobacter
pylori) 		3 / 3 GLY A  27
GLU A 224
ASN A  52
 None
 0.73A 1zq9A-3rrlA:
undetectable		 1zq9A-3rrlA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Helicobacter
pylori) 		4 / 8 TYR A 209
SER A 159
GLN A 211
ILE A 154
 None
 1.09A 2xz5B-3rrlA:
undetectable
2xz5E-3rrlA:
undetectable		 2xz5B-3rrlA:
20.87
2xz5E-3rrlA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Helicobacter
pylori) 		4 / 7 SER A 159
ILE A 213
PRO A 206
GLY A 207
 None
 0.98A 2y7kA-3rrlA:
undetectable		 2y7kA-3rrlA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Helicobacter
pylori) 		4 / 7 ARG B  89
ALA A 104
ASN A 106
PRO A  99
 None
 1.10A 2zgwA-3rrlB:
undetectable		 2zgwA-3rrlB:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Helicobacter
pylori) 		5 / 9 VAL A  96
LEU A 103
ILE A 147
ILE A 142
GLY A 130
 None
 1.16A 3cv9A-3rrlA:
undetectable		 3cv9A-3rrlA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Helicobacter
pylori) 		4 / 6 VAL A  49
ILE A  36
ILE A  21
LEU A  22
 None
 0.68A 3hegA-3rrlA:
undetectable		 3hegA-3rrlA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Helicobacter
pylori) 		4 / 8 GLY A  62
LEU A  64
LEU A  65
ILE A  70
 None
 0.78A 3nbqC-3rrlA:
undetectable		 3nbqC-3rrlA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Helicobacter
pylori) 		3 / 3 ASN B  64
ALA B  65
LYS B  67
 None
 0.95A 3runA-3rrlB:
undetectable		 3runA-3rrlB:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
(Helicobacter
pylori) 		5 / 12 GLY A  25
GLY A  30
ASN A  52
ILE A  21
THR A  20
 None
 1.21A 4n48B-3rrlA:
undetectable		 4n48B-3rrlA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Helicobacter
pylori) 		4 / 6 SER B 191
LEU B 192
ASP B 193
LEU B 186
 None
 0.81A 4wozA-3rrlB:
undetectable
4wozB-3rrlB:
undetectable		 4wozA-3rrlB:
23.55
4wozB-3rrlB:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 3rrl SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A
SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
B
(Helicobacter
pylori) 		4 / 6 ASP B  83
THR A 119
PRO A 120
THR A 121
 None
 1.15A 4yoaA-3rrlB:
undetectable		 4yoaA-3rrlB:
21.67