SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rrt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3rrt FUSION GLYCOPROTEIN
F0
(Human
orthopneumovirus) 		4 / 8 SER B 287
SER B 248
TYR B 299
PHE B 237
 None
 1.20A 1eqbA-3rrtB:
undetectable
1eqbB-3rrtB:
undetectable		 1eqbA-3rrtB:
22.49
1eqbB-3rrtB:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3rrt FUSION GLYCOPROTEIN
F0
(Human
orthopneumovirus) 		4 / 8 TYR B 299
PHE B 237
SER B 287
SER B 248
 None
 1.22A 1eqbA-3rrtB:
undetectable
1eqbB-3rrtB:
undetectable		 1eqbA-3rrtB:
22.49
1eqbB-3rrtB:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3rrt FUSION GLYCOPROTEIN
F0
(Human
orthopneumovirus) 		4 / 8 SER B 287
SER B 248
TYR B 299
PHE B 237
 None
 1.21A 1eqbC-3rrtB:
undetectable
1eqbD-3rrtB:
undetectable		 1eqbC-3rrtB:
22.49
1eqbD-3rrtB:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3rrt FUSION GLYCOPROTEIN
F0
(Human
orthopneumovirus) 		4 / 8 TYR B 299
PHE B 237
SER B 287
SER B 248
 None
 1.22A 1eqbC-3rrtB:
undetectable
1eqbD-3rrtB:
undetectable		 1eqbC-3rrtB:
22.49
1eqbD-3rrtB:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3rrt FUSION GLYCOPROTEIN
F0
(Human
orthopneumovirus) 		4 / 8 VAL B 450
TYR B 458
VAL B 442
ILE B 407
 None
 0.98A 4aftD-3rrtB:
undetectable
4aftE-3rrtB:
undetectable		 4aftD-3rrtB:
20.74
4aftE-3rrtB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3rrt FUSION GLYCOPROTEIN
F0
(Human
orthopneumovirus) 		4 / 7 ILE B 261
LEU B 257
LEU B 252
PRO B 304
 None
 0.81A 5u4sA-3rrtB:
undetectable		 5u4sA-3rrtB:
18.68