SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rs1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SAN_A_ZMRA901_2 (NEURAMINIDASE)	3rs1	C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER I (Mus musculus)	4 / 5	ASP A 147 ARG A 198 TRP A 149 ILE A 196	CL A 301 (-4.9A) None None None	1.43A	3sanA-3rs1A: undetectable	3sanA-3rs1A: 18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SAN_B_ZMRB901_2 (NEURAMINIDASE)	3rs1	C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER I (Mus musculus)	4 / 5	ASP A 147 ARG A 198 TRP A 149 ILE A 196	CL A 301 (-4.9A) None None None	1.45A	3sanB-3rs1A: undetectable	3sanB-3rs1A: 18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E7C_D_ACTD504_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	3rs1	C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER I (Mus musculus)	3 / 3	GLY A 108 SER A 107 TRP A 200	None	0.99A	4e7cD-3rs1A: undetectable	4e7cD-3rs1A: 13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWR_A_ZMRA513_2 (NEURAMINIDASE)	3rs1	C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER I (Mus musculus)	4 / 5	ASP A 147 ARG A 198 TRP A 149 ILE A 196	CL A 301 (-4.9A) None None None	1.46A	4mwrA-3rs1A: undetectable	4mwrA-3rs1A: 15.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3SAN_A_ZMRA901_2","NEURAMINIDASE","3rs1","C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER I","Mus musculus",4,"ASP A 147;ARG A 198;TRP A 149;ILE A 196"," CL A 301 (-4.9A);None;None;None","1.43A","3sanA-3rs1A:undetectable","3sanA-3rs1A:18.01"],["3SAN_B_ZMRB901_2","NEURAMINIDASE","3rs1","C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER I","Mus musculus",4,"ASP A 147;ARG A 198;TRP A 149;ILE A 196"," CL A 301 (-4.9A);None;None;None","1.45A","3sanB-3rs1A:undetectable","3sanB-3rs1A:18.01"],["4E7C_D_ACTD504_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","3rs1","C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER I","Mus musculus",3,"GLY A 108;SER A 107;TRP A 200","None","0.99A","4e7cD-3rs1A:undetectable","4e7cD-3rs1A:13.83"],["4MWR_A_ZMRA513_2","NEURAMINIDASE","3rs1","C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER I","Mus musculus",4,"ASP A 147;ARG A 198;TRP A 149;ILE A 196"," CL A 301 (-4.9A);None;None;None","1.46A","4mwrA-3rs1A:undetectable","4mwrA-3rs1A:15.53"]]