SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rsi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3rsi PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 6 LEU A   7
LEU A  82
MET A 116
LEU A  29
 None
 0.62A 1z95A-3rsiA:
undetectable		 1z95A-3rsiA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 3rsi PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 9 LEU A 169
ILE A 154
ALA A 159
GLY A 111
LEU A 133
 None
None
None
IOD  A 263 ( 4.1A)
None
 1.18A 2v0mB-3rsiA:
undetectable		 2v0mB-3rsiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 3rsi PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 GLY A 260
ARG A 244
GLU A 245
ALA A 249
ARG A 254
 None
 1.38A 3jzjA-3rsiA:
undetectable		 3jzjA-3rsiA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 3rsi PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 10 GLN A 118
LEU A 150
LEU A 179
LEU A 169
LEU A 117
 None
 1.19A 4yiaA-3rsiA:
undetectable		 4yiaA-3rsiA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3rsi PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		3 / 3 VAL A 124
ARG A  51
PRO A 100
 None
 0.83A 5koxA-3rsiA:
undetectable		 5koxA-3rsiA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_F_ACTF503_0
(METHYL-VIOLOGEN
REDUCING HYDROGENASE
SUBUNIT A)		 3rsi PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 4 ARG A  11
VAL A  16
ASP A  47
LYS A  99
 None
 1.50A 5odcF-3rsiA:
0.0		 5odcF-3rsiA:
21.91