SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rty'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 DTT  A 900 (-4.9A)
None
None
 0.52A 1q23C-3rtyA:
undetectable		 1q23C-3rtyA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 DTT  A 900 (-4.9A)
None
None
 0.59A 1q23H-3rtyA:
undetectable		 1q23H-3rtyA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 DTT  A 900 (-4.9A)
None
None
 0.51A 1q23G-3rtyA:
undetectable		 1q23G-3rtyA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 DTT  A 900 (-4.9A)
None
None
 0.59A 1q23L-3rtyA:
undetectable		 1q23L-3rtyA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		3 / 3 VAL A 409
ALA A 408
HIS A 493
 DTT  A 900 (-4.9A)
None
None
 0.54A 1q23J-3rtyA:
undetectable		 1q23J-3rtyA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 8 THR A 476
GLY A 447
THR A 449
ALA A 450
 None
 0.84A 2a1hA-3rtyA:
undetectable
2a1hB-3rtyA:
undetectable		 2a1hA-3rtyA:
20.94
2a1hB-3rtyA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 0.95A 3bjwA-3rtyA:
undetectable		 3bjwA-3rtyA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 0.94A 3bjwG-3rtyA:
undetectable		 3bjwG-3rtyA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 0.93A 3bjwC-3rtyA:
undetectable		 3bjwC-3rtyA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 489
VAL A 490
THR A 439
THR A 396
 None
 0.97A 3bjwD-3rtyA:
undetectable		 3bjwD-3rtyA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 6 GLY A 421
PHE A 427
ILE A 424
PHE A 461
 None
 1.04A 4qogA-3rtyA:
undetectable
4qogB-3rtyA:
undetectable		 4qogA-3rtyA:
20.90
4qogB-3rtyA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 5 TYR A 459
GLY A 491
TYR A 428
GLY A 399
 None
 0.98A 5ayfA-3rtyA:
undetectable		 5ayfA-3rtyA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 3rty PERIOD CIRCADIAN
PROTEIN
(Drosophila
melanogaster) 		4 / 8 GLY A 447
GLN A 448
THR A 449
SER A 477
 None
 1.17A 6eqpA-3rtyA:
undetectable		 6eqpA-3rtyA:
15.66