SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rui'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3rui UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7
(Saccharomyces
cerevisiae) 		5 / 11 PHE A 353
GLY A 333
ALA A 368
LEU A 369
ALA A 298
 None
 1.01A 4l6v1-3ruiA:
undetectable
4l6v6-3ruiA:
undetectable		 4l6v1-3ruiA:
18.21
4l6v6-3ruiA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3rui UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 437
LEU A 448
SER A 447
ILE A 452
 None
 0.99A 5jw1A-3ruiA:
undetectable		 5jw1A-3ruiA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 3rui UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7
(Saccharomyces
cerevisiae) 		4 / 4 PHE A 353
ASP A 355
LEU A 369
LYS A 379
 None
 1.28A 6awvA-3ruiA:
undetectable		 6awvA-3ruiA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 3rui UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7
(Saccharomyces
cerevisiae) 		3 / 3 ILE A 433
ASN A 474
CYH A 572
 None
None
ZN  A   1 (-2.3A)
 0.85A 6bp4A-3ruiA:
undetectable		 6bp4A-3ruiA:
20.11