SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 3rv0 K. POLYSPORUS DCR1
(Vanderwaltozyma
polyspora) 		3 / 3 ASP A  62
LEU A  52
LEU A  54
 None
 0.52A 1ikeA-3rv0A:
undetectable		 1ikeA-3rv0A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 3rv0 K. POLYSPORUS DCR1
(Vanderwaltozyma
polyspora) 		3 / 3 ASP A  62
LEU A  52
LEU A  54
 None
 0.56A 1np1B-3rv0A:
undetectable		 1np1B-3rv0A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 3rv0 K. POLYSPORUS DCR1
(Vanderwaltozyma
polyspora) 		4 / 5 LEU A  66
ASP A  62
ILE A  65
GLY A  55
 None
 0.50A 3bufA-3rv0A:
undetectable		 3bufA-3rv0A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3rv0 K. POLYSPORUS DCR1
(Vanderwaltozyma
polyspora) 		3 / 3 ASP A 103
LEU A 230
ARG A 234
 None
 0.95A 5e8qA-3rv0A:
undetectable		 5e8qA-3rv0A:
18.48