SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ry6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 3ry6 LOW AFFINITY
IMMUNOGLOBULIN GAMMA
FC REGION RECEPTOR
II-A
(Homo
sapiens) 		4 / 5 THR C  95
ILE C  17
PHE C 100
LEU C  98
 None
 1.24A 3tf1A-3ry6C:
undetectable		 3tf1A-3ry6C:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3ry6 LOW AFFINITY
IMMUNOGLOBULIN GAMMA
FC REGION RECEPTOR
II-A
(Homo
sapiens) 		3 / 3 TRP C  90
VAL C  92
TRP C 113
 None
 1.48A 3zq8A-3ry6C:
undetectable
3zq8B-3ry6C:
undetectable		 3zq8A-3ry6C:
9.43
3zq8B-3ry6C:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3ry6 LOW AFFINITY
IMMUNOGLOBULIN GAMMA
FC REGION RECEPTOR
II-A
(Homo
sapiens) 		3 / 3 TRP C 113
VAL C  92
TRP C  90
 None
 1.32A 3zq8A-3ry6C:
undetectable
3zq8B-3ry6C:
undetectable		 3zq8A-3ry6C:
9.43
3zq8B-3ry6C:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 3ry6 LOW AFFINITY
IMMUNOGLOBULIN GAMMA
FC REGION RECEPTOR
II-A
(Homo
sapiens) 		4 / 5 ALA C 144
HIS C 148
GLN C 125
TYR C 152
 None
NDG  C 200 (-4.5A)
None
None
 1.39A 4gboA-3ry6C:
undetectable		 4gboA-3ry6C:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3ry6 LOW AFFINITY
IMMUNOGLOBULIN GAMMA
FC REGION RECEPTOR
II-A
(Homo
sapiens) 		4 / 5 VAL C  86
HIS C  44
LEU C  12
ASP C  65
 None
 1.32A 5vcvA-3ry6C:
undetectable		 5vcvA-3ry6C:
20.26