SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ryt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		3 / 3 ALA C  59
VAL C   9
TRP C  97
 None
 0.86A 1jnoA-3rytC:
undetectable		 1jnoA-3rytC:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		3 / 3 ALA C  59
VAL C   9
TRP C  97
 None
 0.86A 1jnoB-3rytC:
undetectable		 1jnoB-3rytC:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		3 / 3 ALA C  59
VAL C   9
TRP C  97
 None
 0.90A 1magA-3rytC:
undetectable		 1magA-3rytC:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		3 / 3 ALA C  59
VAL C   9
TRP C  97
 None
 0.90A 1magB-3rytC:
undetectable		 1magB-3rytC:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		3 / 3 ALA C  59
VAL C   9
TRP C  97
 None
 0.88A 1ng8A-3rytC:
undetectable		 1ng8A-3rytC:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		3 / 3 ALA C  59
VAL C   9
TRP C  97
 None
 0.88A 1ng8B-3rytC:
undetectable		 1ng8B-3rytC:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		3 / 3 ALA C  59
VAL C   9
TRP C  97
 None
 0.94A 1nruA-3rytC:
undetectable		 1nruA-3rytC:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		3 / 3 ALA C  59
VAL C   9
TRP C  97
 None
 0.94A 1nruB-3rytC:
undetectable		 1nruB-3rytC:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 3ryt PLEXIN-A1
(Mus
musculus) 		3 / 3 LEU A1409
LEU A1439
MET A1392
 None
 0.68A 1ya3B-3rytA:
undetectable		 1ya3B-3rytA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 11 LEU A1413
ILE A1414
ASN A1417
LEU A1428
SER A1433
 None
 0.98A 2bxeA-3rytA:
undetectable		 2bxeA-3rytA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 12 LEU A1413
ILE A1414
ASN A1417
LEU A1428
SER A1433
 None
 0.92A 2bxeB-3rytA:
3.5		 2bxeB-3rytA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 3ryt PLEXIN-A1
(Mus
musculus) 		3 / 3 MET A1470
VAL A1518
GLU A1531
 None
 0.66A 2x9gA-3rytA:
undetectable		 2x9gA-3rytA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 12 VAL A1529
ASP A1570
VAL A1571
ASN A1583
TYR A1588
 None
 1.43A 2y00A-3rytA:
undetectable		 2y00A-3rytA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ryt PLEXIN-A1
(Mus
musculus) 		4 / 5 GLN A1589
THR A1525
HIS A1653
HIS A1587
 None
 1.30A 3g1uC-3rytA:
undetectable		 3g1uC-3rytA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 11 LEU A1688
LEU A1799
LYS A1794
ILE A1466
SER A1487
 None
 1.45A 3h6tA-3rytA:
undetectable
3h6tC-3rytA:
undetectable		 3h6tA-3rytA:
18.87
3h6tC-3rytA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 11 ILE A1466
SER A1487
LEU A1688
LEU A1799
LYS A1794
 None
 1.46A 3h6tA-3rytA:
undetectable
3h6tC-3rytA:
undetectable		 3h6tA-3rytA:
18.87
3h6tC-3rytA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 12 LEU A1395
GLY A1357
PHE A1365
LEU A1366
TYR A1401
 None
 1.22A 3mecA-3rytA:
undetectable		 3mecA-3rytA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 12 LEU A1833
PHE A1443
LEU A1446
PRO A1710
TYR A1832
 None
 1.23A 3mecA-3rytA:
undetectable		 3mecA-3rytA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 3ryt PLEXIN-A1
(Mus
musculus) 		6 / 12 ASN A1796
LEU A1771
ILE A1466
MET A1470
SER A1485
VAL A1773
 None
 1.47A 3nk7B-3rytA:
undetectable		 3nk7B-3rytA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		 3ryt PLEXIN-A1
(Mus
musculus) 		4 / 5 CYH A1464
TYR A1543
PRO A1318
THR A1309
 None
 1.45A 3q07A-3rytA:
undetectable		 3q07A-3rytA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 3ryt PLEXIN-A1
(Mus
musculus) 		4 / 5 CYH A1464
TYR A1543
PRO A1318
THR A1309
 None
 1.46A 3q07B-3rytA:
undetectable		 3q07B-3rytA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3ryt PLEXIN-A1
(Mus
musculus) 		4 / 5 TYR A1463
ILE A1492
LEU A1491
LYS A1490
 None
 0.93A 3sueC-3rytA:
undetectable		 3sueC-3rytA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 11 ILE A1818
ASP A1721
LEU A1720
PHE A1717
LEU A1743
 None
 1.32A 4i1nA-3rytA:
undetectable		 4i1nA-3rytA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 9 LEU A1720
ILE A1713
LEU A1447
ILE A1818
PHE A1747
 None
 1.10A 4kukA-3rytA:
undetectable		 4kukA-3rytA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3ryt PLEXIN-A1
(Mus
musculus) 		4 / 7 LEU A1771
THR A1767
PRO A1755
ILE A1761
 None
 1.05A 5fxtA-3rytA:
undetectable		 5fxtA-3rytA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		5 / 12 VAL C 101
LEU C  19
LEU C  79
LEU C  20
THR C  17
 None
None
None
None
GNP  C 179 ( 3.6A)
 1.18A 5hnwB-3rytC:
undetectable		 5hnwB-3rytC:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ryt PLEXIN-A1
(Mus
musculus) 		4 / 4 GLN A1528
THR A1527
THR A1573
LEU A1651
 None
 1.46A 5m5kA-3rytA:
undetectable		 5m5kA-3rytA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ryt PLEXIN-A1
(Mus
musculus) 		4 / 4 GLN A1528
THR A1527
THR A1573
LEU A1651
 None
 1.48A 5m5kC-3rytA:
undetectable		 5m5kC-3rytA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 12 VAL A1529
ASP A1570
VAL A1571
ASN A1583
TYR A1588
 None
 1.49A 6h7lA-3rytA:
undetectable		 6h7lA-3rytA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3ryt PLEXIN-A1
(Mus
musculus) 		5 / 12 VAL A1529
ASP A1570
VAL A1571
ASN A1583
TYR A1588
 None
 1.47A 6h7lB-3rytA:
undetectable		 6h7lB-3rytA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ryt RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE 1
(Homo
sapiens) 		4 / 7 ARG C  68
TYR C  72
ASP C  65
GLU C  62
 None
 1.27A 6mn5B-3rytC:
undetectable		 6mn5B-3rytC:
20.34