SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 8 HIS A 396
ILE A 387
HIS A 350
HIS A 398
 ZN  A   2 (-3.5A)
None
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.94A 1ei6D-3rzuA:
undetectable		 1ei6D-3rzuA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 411
LEU A 263
LEU A 285
SER A 362
THR A 374
 None
 1.08A 1qzfA-3rzuA:
undetectable		 1qzfA-3rzuA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 411
LEU A 263
LEU A 285
SER A 362
THR A 374
 None
 1.08A 1qzfB-3rzuA:
undetectable		 1qzfB-3rzuA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 411
LEU A 263
LEU A 285
SER A 362
THR A 374
 None
 1.08A 1qzfC-3rzuA:
undetectable		 1qzfC-3rzuA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 411
LEU A 263
LEU A 285
SER A 362
THR A 374
 None
 1.09A 1qzfD-3rzuA:
undetectable		 1qzfD-3rzuA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 411
LEU A 263
LEU A 285
SER A 362
THR A 374
 None
 1.09A 1qzfE-3rzuA:
undetectable		 1qzfE-3rzuA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.75A 1v54A-3rzuA:
undetectable		 1v54A-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.76A 1v54N-3rzuA:
undetectable		 1v54N-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.73A 1v55A-3rzuA:
undetectable		 1v55A-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.74A 1v55N-3rzuA:
undetectable		 1v55N-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.74A 2dyrA-3rzuA:
undetectable		 2dyrA-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.76A 2dyrN-3rzuA:
undetectable		 2dyrN-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.72A 2eijA-3rzuA:
undetectable		 2eijA-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.75A 2eijN-3rzuA:
undetectable		 2eijN-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.73A 2eikA-3rzuA:
undetectable		 2eikA-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.74A 2eimA-3rzuA:
undetectable		 2eimA-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.75A 2eimN-3rzuA:
undetectable		 2eimN-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 411
LEU A 263
LEU A 285
SER A 362
THR A 374
 None
 1.14A 2oipA-3rzuA:
undetectable		 2oipA-3rzuA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 398
HIS A 396
HIS A 350
 ZN  A   2 (-3.4A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
 0.54A 2ozrF-3rzuA:
undetectable		 2ozrF-3rzuA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 6 GLN A 304
ALA A 273
THR A 336
PHE A 267
 None
 1.04A 2xfhA-3rzuA:
undetectable		 2xfhA-3rzuA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.77A 2zxwA-3rzuA:
undetectable		 2zxwA-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.74A 3abmA-3rzuA:
undetectable		 3abmA-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.70A 3ag1A-3rzuA:
undetectable		 3ag1A-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.75A 3ag1N-3rzuA:
undetectable		 3ag1N-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.76A 3ag3N-3rzuA:
undetectable		 3ag3N-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.69A 3ag4A-3rzuA:
undetectable		 3ag4A-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.74A 3ag4N-3rzuA:
undetectable		 3ag4N-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.74A 3dtuA-3rzuA:
undetectable		 3dtuA-3rzuA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 411
LEU A 263
LEU A 285
SER A 362
THR A 374
 None
 1.13A 3hj3C-3rzuA:
undetectable		 3hj3C-3rzuA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 411
LEU A 263
LEU A 285
SER A 362
THR A 374
 None
 1.08A 3hj3D-3rzuA:
undetectable		 3hj3D-3rzuA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_C_RFPC1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		5 / 12 ASP A 252
HIS A 410
LEU A 289
PRO A 249
ASN A 292
 None
 1.41A 4kmuC-3rzuA:
undetectable		 4kmuC-3rzuA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.72A 5b1bA-3rzuA:
undetectable		 5b1bA-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.75A 5b1bN-3rzuA:
undetectable		 5b1bN-3rzuA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 5 HIS A 335
HIS A 337
VAL A 366
ALA A 364
 ZN  A   1 (-3.5A)
ZN  A   1 (-3.4A)
None
None
 1.23A 5i3bB-3rzuA:
undetectable		 5i3bB-3rzuA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 8 GLY A 375
ILE A 365
ASP A 348
HIS A 352
 None
None
ZN  A   1 (-2.2A)
None
 1.05A 6ag0C-3rzuA:
undetectable		 6ag0C-3rzuA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzu STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.5A)
ZN  A   2 (-3.5A)
ZN  A   2 (-3.4A)
 0.72A 6nmfA-3rzuA:
undetectable		 6nmfA-3rzuA:
16.83