SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rzv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 8 HIS A 396
ILE A 387
HIS A 350
HIS A 398
 ZN  A   2 (-3.2A)
None
ZN  A   2 (-3.3A)
ZN  A   2 (-3.2A)
 0.95A 1ei6D-3rzvA:
undetectable		 1ei6D-3rzvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 4 ALA A 306
VAL A 279
ALA A 280
HIS A 335
 None
None
None
ZN  A   1 (-3.3A)
 1.25A 1q23K-3rzvA:
undetectable		 1q23K-3rzvA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-3.2A)
 0.74A 2eimN-3rzvA:
undetectable		 2eimN-3rzvA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 263
ASP A 415
LEU A 331
HIS A 298
 None
 1.29A 2jfaA-3rzvA:
undetectable		 2jfaA-3rzvA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 263
ASP A 415
LEU A 331
HIS A 298
 None
 1.28A 2qxsA-3rzvA:
undetectable		 2qxsA-3rzvA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 263
ASP A 415
LEU A 331
HIS A 298
 None
 1.30A 2qxsB-3rzvA:
undetectable		 2qxsB-3rzvA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 GLN A 323
THR A 313
TRP A 333
 None
 0.99A 2rctA-3rzvA:
undetectable		 2rctA-3rzvA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 6 GLN A 304
ALA A 273
THR A 336
PHE A 267
 None
 1.03A 2xfhA-3rzvA:
undetectable		 2xfhA-3rzvA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-3.2A)
 0.73A 3ag1A-3rzvA:
undetectable		 3ag1A-3rzvA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-3.2A)
 0.73A 3ag4A-3rzvA:
undetectable		 3ag4A-3rzvA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 350
HIS A 396
HIS A 398
 ZN  A   2 (-3.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-3.2A)
 0.76A 3ag4N-3rzvA:
undetectable		 3ag4N-3rzvA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 5 HIS A 335
HIS A 337
VAL A 366
ALA A 364
 ZN  A   1 (-3.3A)
ZN  A   1 (-3.3A)
None
None
 1.23A 5i3bB-3rzvA:
undetectable		 5i3bB-3rzvA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		3 / 3 HIS A 398
HIS A 396
HIS A 350
 ZN  A   2 (-3.2A)
ZN  A   2 (-3.2A)
ZN  A   2 (-3.3A)
 0.62A 5zrdA-3rzvA:
undetectable		 5zrdA-3rzvA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3rzv STAM-BINDING PROTEIN
(Homo
sapiens) 		4 / 8 GLY A 375
ILE A 365
ASP A 348
HIS A 352
 None
None
ZN  A   1 (-2.1A)
None
 0.93A 6ag0A-3rzvA:
undetectable		 6ag0A-3rzvA:
14.22