SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s0m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 TRP A 102
ALA A 100
VAL A 154
 None
 0.88A 1av2C-3s0mA:
undetectable
1av2D-3s0mA:
undetectable		 1av2C-3s0mA:
4.42
1av2D-3s0mA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		5 / 12 GLY A 311
GLN A 282
THR A  55
PHE A  50
LEU A  73
 None
 1.49A 1m2zD-3s0mA:
undetectable		 1m2zD-3s0mA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 GLU A 280
HIS A 319
HIS A 275
 MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.4A)
 0.67A 1oe2A-3s0mA:
1.6		 1oe2A-3s0mA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 5 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.12A 1os2A-3s0mA:
undetectable		 1os2A-3s0mA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.14A 1os2D-3s0mA:
undetectable		 1os2D-3s0mA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 5 TYR A 283
SER A  81
HIS A  95
HIS A 140
 None
None
MN  A 500 ( 3.3A)
MN  A 500 (-3.5A)
 1.46A 1s19A-3s0mA:
undetectable		 1s19A-3s0mA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		5 / 11 LEU A 329
ARG A 270
HIS A 273
HIS A 319
VAL A 262
 None
None
MN  A 501 (-3.5A)
MN  A 501 (-3.4A)
None
 1.41A 1tmxA-3s0mA:
undetectable		 1tmxA-3s0mA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.15A 1utzA-3s0mA:
undetectable		 1utzA-3s0mA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.19A 1utzB-3s0mA:
undetectable		 1utzB-3s0mA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_A_H4BA1003_1
(HYPOTHETICAL PROTEIN
PH0634)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		5 / 10 HIS A 319
HIS A 273
HIS A 275
GLU A 280
TYR A 284
 MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
None
 1.08A 2dttA-3s0mA:
undetectable
2dttC-3s0mA:
undetectable		 2dttA-3s0mA:
16.44
2dttC-3s0mA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_A_H4BA1003_1
(HYPOTHETICAL PROTEIN
PH0634)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		5 / 10 HIS A 319
HIS A 273
HIS A 275
GLU A 280
TYR A 305
 MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
None
 1.48A 2dttA-3s0mA:
undetectable
2dttC-3s0mA:
undetectable		 2dttA-3s0mA:
16.44
2dttC-3s0mA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_B_NCAB901_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 5 ILE A  75
PRO A 314
PHE A 303
VAL A  45
 None
 1.45A 2hjhB-3s0mA:
undetectable		 2hjhB-3s0mA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.14A 2hu6A-3s0mA:
undetectable		 2hu6A-3s0mA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.15A 2ow9B-3s0mA:
undetectable		 2ow9B-3s0mA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.12A 2ozrC-3s0mA:
undetectable		 2ozrC-3s0mA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.11A 2ozrD-3s0mA:
undetectable		 2ozrD-3s0mA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 8 LYS A 375
HIS A 273
ASP A 342
ALA A 260
 None
MN  A 501 (-3.5A)
None
None
 1.37A 2rk8A-3s0mA:
undetectable		 2rk8A-3s0mA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.73A 3abkA-3s0mA:
undetectable		 3abkA-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.73A 3abkN-3s0mA:
undetectable		 3abkN-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.73A 3ag1A-3s0mA:
undetectable		 3ag1A-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.75A 3ag1N-3s0mA:
undetectable		 3ag1N-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.74A 3ag2A-3s0mA:
undetectable		 3ag2A-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.75A 3ag2N-3s0mA:
undetectable		 3ag2N-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.75A 3ag3A-3s0mA:
undetectable		 3ag3A-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.75A 3ag3N-3s0mA:
undetectable		 3ag3N-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.73A 3ag4A-3s0mA:
undetectable		 3ag4A-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.75A 3ag4N-3s0mA:
undetectable		 3ag4N-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.75A 3asnA-3s0mA:
undetectable		 3asnA-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.76A 3asoA-3s0mA:
undetectable		 3asoA-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.17A 3lilA-3s0mA:
undetectable		 3lilA-3s0mA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 5 HIS A  95
THR A 113
GLU A 101
ASP A 156
 MN  A 500 ( 3.3A)
None
MN  A 500 (-2.7A)
None
 1.36A 3tm4A-3s0mA:
undetectable		 3tm4A-3s0mA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 5 HIS A  95
THR A 113
GLU A 101
ASP A 156
 MN  A 500 ( 3.3A)
None
MN  A 500 (-2.7A)
None
 1.36A 3tm4B-3s0mA:
undetectable		 3tm4B-3s0mA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.74A 3x2qA-3s0mA:
undetectable		 3x2qA-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 PHE A 155
VAL A  82
ALA A  80
PHE A  52
 CO3  A 600 (-4.6A)
None
None
None
 1.45A 4f3tA-3s0mA:
undetectable		 4f3tA-3s0mA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 ARG A  92
HIS A  95
TYR A 200
 CO3  A 600 (-4.0A)
MN  A 500 ( 3.3A)
None
 0.97A 4fu8A-3s0mA:
undetectable		 4fu8A-3s0mA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 ARG A  92
HIS A  95
TYR A 200
 CO3  A 600 (-4.0A)
MN  A 500 ( 3.3A)
None
 0.92A 4fu9A-3s0mA:
undetectable		 4fu9A-3s0mA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		5 / 11 HIS A 273
HIS A 275
HIS A 319
VAL A 321
LEU A 329
 MN  A 501 (-3.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.4A)
None
None
 1.24A 4k0sA-3s0mA:
undetectable		 4k0sA-3s0mA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 5 GLU A  67
VAL A  82
VAL A 165
PHE A 155
 None
None
None
CO3  A 600 (-4.6A)
 1.02A 4lb0B-3s0mA:
undetectable		 4lb0B-3s0mA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 PHE A 155
VAL A  82
ALA A  80
PHE A  52
 CO3  A 600 (-4.6A)
None
None
None
 1.47A 4w5qA-3s0mA:
undetectable		 4w5qA-3s0mA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 PHE A 155
VAL A  82
ALA A  80
PHE A  52
 CO3  A 600 (-4.6A)
None
None
None
 1.45A 4w5rA-3s0mA:
undetectable		 4w5rA-3s0mA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 PHE A 155
VAL A  82
ALA A  80
PHE A  52
 CO3  A 600 (-4.6A)
None
None
None
 1.46A 4w5tA-3s0mA:
undetectable		 4w5tA-3s0mA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 PHE A 155
VAL A  82
ALA A  80
PHE A  52
 CO3  A 600 (-4.6A)
None
None
None
 1.46A 4z4gA-3s0mA:
undetectable		 4z4gA-3s0mA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		5 / 12 GLY A 129
GLY A 127
SER A 109
GLY A 108
LEU A 261
 None
 1.06A 5c0oH-3s0mA:
undetectable		 5c0oH-3s0mA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 PHE A 155
VAL A  82
ALA A  80
PHE A  52
 CO3  A 600 (-4.6A)
None
None
None
 1.45A 5ki6A-3s0mA:
undetectable		 5ki6A-3s0mA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 4 HIS A 319
GLU A 280
HIS A 275
HIS A 273
 MN  A 501 (-3.4A)
MN  A 501 (-2.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.5A)
 1.17A 5n5jA-3s0mA:
undetectable		 5n5jA-3s0mA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.72A 5x19A-3s0mA:
undetectable		 5x19A-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.72A 5x19N-3s0mA:
undetectable		 5x19N-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.72A 5x1fA-3s0mA:
undetectable		 5x1fA-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A 273
HIS A 319
HIS A 275
 MN  A 501 (-3.5A)
MN  A 501 (-3.4A)
MN  A 501 (-3.4A)
 0.44A 5zrdA-3s0mA:
undetectable		 5zrdA-3s0mA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		3 / 3 HIS A  97
HIS A 140
HIS A  95
 MN  A 500 ( 3.6A)
MN  A 500 (-3.5A)
MN  A 500 ( 3.3A)
 0.73A 6giqa-3s0mA:
undetectable		 6giqa-3s0mA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3s0m OXALATE
DECARBOXYLASE OXDC
(Bacillus
subtilis) 		4 / 6 TYR A 320
ALA A 289
ARG A 290
ASP A  41
 None
 1.06A 6hu9m-3s0mA:
undetectable
6hu9q-3s0mA:
undetectable		 6hu9m-3s0mA:
21.17
6hu9q-3s0mA:
16.71