SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		4 / 5 ARG A  74
LYS A  75
ALA A  73
GLY A  68
 None
 0.97A 1e7bA-3s1vA:
undetectable		 1e7bA-3s1vA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		5 / 12 GLU A  67
ASP A  92
ARG A  95
ILE A  87
GLU A  72
 None
 1.31A 1l7fA-3s1vA:
undetectable		 1l7fA-3s1vA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_0
(NEURAMINIDASE)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		5 / 12 GLU A  67
ASP A  92
ARG A  95
ILE A  87
GLU A  72
 None
 1.35A 1l7hA-3s1vA:
undetectable		 1l7hA-3s1vA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		4 / 5 ASP A   6
LEU A  31
ALA A 166
LEU A 164
 F6R  A 226 (-3.0A)
None
F6R  A 226 (-3.3A)
F6R  A 226 ( 4.4A)
 1.14A 1nh8A-3s1vA:
undetectable		 1nh8A-3s1vA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		4 / 8 TYR A 128
SER A 130
ILE A  97
SER A  58
 None
F6R  A 226 (-2.8A)
None
None
 0.95A 2xz5B-3s1vA:
undetectable
2xz5E-3s1vA:
undetectable		 2xz5B-3s1vA:
21.90
2xz5E-3s1vA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		4 / 6 ASN A 170
HIS A 173
PRO A 188
ASP A 138
 GOL  A 224 (-3.7A)
GOL  A 224 (-4.1A)
None
None
 1.27A 3oi8A-3s1vA:
undetectable		 3oi8A-3s1vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		5 / 11 ARG A 176
ILE A 168
VAL A 165
VAL A 133
ILE A 180
 GOL  A 224 ( 3.9A)
None
None
None
GOL  A 225 (-4.7A)
 1.16A 3rf4A-3s1vA:
undetectable
3rf4C-3s1vA:
undetectable		 3rf4A-3s1vA:
19.63
3rf4C-3s1vA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		5 / 11 ILE A 180
ARG A 176
ILE A 168
VAL A 165
VAL A 133
 GOL  A 225 (-4.7A)
GOL  A 224 ( 3.9A)
None
None
None
 1.16A 3rf4A-3s1vA:
undetectable
3rf4B-3s1vA:
undetectable		 3rf4A-3s1vA:
19.63
3rf4B-3s1vA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		5 / 11 ILE A 180
ARG A 176
ILE A 168
VAL A 165
VAL A 133
 GOL  A 225 (-4.7A)
GOL  A 224 ( 3.9A)
None
None
None
 1.17A 3rf4B-3s1vA:
undetectable
3rf4C-3s1vA:
undetectable		 3rf4B-3s1vA:
19.63
3rf4C-3s1vA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		5 / 12 GLU A  67
ASP A  92
ARG A  95
ILE A  87
GLU A  72
 None
 1.30A 4mwvA-3s1vA:
undetectable		 4mwvA-3s1vA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		5 / 12 LEU A 195
ASN A 170
ILE A 168
VAL A 185
VAL A 165
 None
GOL  A 224 (-3.7A)
None
None
None
 1.03A 4nkvA-3s1vA:
undetectable		 4nkvA-3s1vA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		3 / 3 THR A 161
ASN A 114
PHE A 113
 None
 0.83A 4pd9A-3s1vA:
undetectable		 4pd9A-3s1vA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 3s1v PROBABLE
TRANSALDOLASE
(Thermoplasma
acidophilum) 		5 / 9 GLY A  80
HIS A  77
VAL A  59
SER A  58
VAL A  85
 None
 1.20A 4qd3A-3s1vA:
undetectable		 4qd3A-3s1vA:
24.14