SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 TRP A 644
ALA A 579
VAL A 608
 None
 0.93A 1c4dA-3s29A:
undetectable
1c4dB-3s29A:
undetectable		 1c4dA-3s29A:
3.51
1c4dB-3s29A:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 ALA A 579
VAL A 608
TRP A 644
 None
 0.92A 1c4dC-3s29A:
undetectable
1c4dD-3s29A:
undetectable		 1c4dC-3s29A:
3.51
1c4dD-3s29A:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 TRP A 644
ALA A 579
VAL A 608
 None
 0.87A 1c4dC-3s29A:
undetectable
1c4dD-3s29A:
undetectable		 1c4dC-3s29A:
3.51
1c4dD-3s29A:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4001_1
(SERUM ALBUMIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 4 ARG A 614
LYS A 561
ASP A 612
GLY A 611
 None
 1.45A 1e7bB-3s29A:
0.0		 1e7bB-3s29A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 4 ILE A 550
LEU A 567
VAL A 607
ILE A 645
 None
 0.93A 1fm6D-3s29A:
undetectable		 1fm6D-3s29A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 7 LEU A 112
PHE A 117
LEU A 118
ALA A 501
 None
 0.55A 1j8uA-3s29A:
undetectable		 1j8uA-3s29A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 MET A 472
ASN A 473
PHE A 521
ILE A 469
PHE A 139
 None
 1.47A 1p93D-3s29A:
undetectable		 1p93D-3s29A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 GLY A 418
ASP A 417
ASN A 414
HIS A 438
ALA A 439
 None
None
None
None
FRU  A 902 ( 3.7A)
 1.03A 2bm9F-3s29A:
undetectable		 2bm9F-3s29A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 LEU A 581
LEU A 296
MET A 649
 None
UDP  A 901 (-3.7A)
None
 0.77A 2itzA-3s29A:
undetectable		 2itzA-3s29A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_A_T44A128_1
(TRANSTHYRETIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 4 LYS A 169
LEU A 166
ALA A 168
LEU A 268
 None
 1.29A 2roxA-3s29A:
undetectable		 2roxA-3s29A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 7 PHE A 576
ILE A 574
THR A 680
GLY A 610
 None
None
UDP  A 901 (-3.2A)
None
 0.62A 2v0mB-3s29A:
undetectable		 2v0mB-3s29A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 7 TYR A 658
VAL A 681
TYR A 533
ILE A 749
 None
 1.20A 2xz5B-3s29A:
undetectable
2xz5E-3s29A:
undetectable		 2xz5B-3s29A:
12.27
2xz5E-3s29A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 8 ILE A 749
TYR A 658
VAL A 681
TYR A 533
 None
 1.18A 2xz5A-3s29A:
undetectable
2xz5C-3s29A:
undetectable		 2xz5A-3s29A:
12.27
2xz5C-3s29A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 8 ILE A 749
TYR A 658
VAL A 681
TYR A 533
 None
 1.21A 2xz5C-3s29A:
undetectable
2xz5D-3s29A:
undetectable		 2xz5C-3s29A:
12.27
2xz5D-3s29A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 7 ILE A 749
TYR A 658
VAL A 681
TYR A 533
 None
 1.19A 2xz5D-3s29A:
undetectable
2xz5E-3s29A:
undetectable		 2xz5D-3s29A:
12.27
2xz5E-3s29A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 11 THR A 393
LEU A 429
LEU A 284
ILE A 411
LEU A 404
 None
 1.32A 3a50C-3s29A:
undetectable		 3a50C-3s29A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 ASN A 143
ASP A 476
GLN A 433
 None
 0.82A 3eeyC-3s29A:
2.7		 3eeyC-3s29A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 ASN A 143
ASP A 476
GLN A 433
 None
 0.80A 3eeyD-3s29A:
undetectable		 3eeyD-3s29A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 ASN A 143
ASP A 476
GLN A 433
 None
 0.82A 3eeyE-3s29A:
2.7		 3eeyE-3s29A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 5 PRO A 714
THR A 680
VAL A 681
GLY A 678
 None
UDP  A 901 (-3.2A)
None
UDP  A 901 ( 3.7A)
 1.03A 3elzA-3s29A:
undetectable		 3elzA-3s29A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IEO_A_AMJA300_0
(CARBONIC ANHYDRASE 2)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 4 ILE A 364
GLN A 292
VAL A 356
PHE A 290
 None
 1.30A 3ieoA-3s29A:
undetectable		 3ieoA-3s29A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.99A 3keeA-3s29A:
undetectable		 3keeA-3s29A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 1.11A 3keeA-3s29A:
undetectable		 3keeA-3s29A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.94A 3keeB-3s29A:
undetectable		 3keeB-3s29A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.94A 3keeC-3s29A:
undetectable		 3keeC-3s29A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.92A 3keeD-3s29A:
undetectable		 3keeD-3s29A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 6 TYR A 307
GLN A 304
ILE A 308
SER A 481
 None
FRU  A 902 (-4.0A)
None
None
 1.12A 3pmzD-3s29A:
undetectable		 3pmzD-3s29A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 5 PHE A 483
ILE A 486
GLY A  95
HIS A 152
 None
 1.07A 3r0lD-3s29A:
undetectable		 3r0lD-3s29A:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.94A 3sudA-3s29A:
undetectable		 3sudA-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.85A 3sudC-3s29A:
undetectable		 3sudC-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.90A 3sudD-3s29A:
undetectable		 3sudD-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 1.01A 3sudD-3s29A:
undetectable		 3sudD-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.83A 3sueA-3s29A:
undetectable		 3sueA-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 0.99A 3sueA-3s29A:
undetectable		 3sueA-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.95A 3sueB-3s29A:
undetectable		 3sueB-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 1.02A 3sueB-3s29A:
undetectable		 3sueB-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.89A 3sueC-3s29A:
undetectable		 3sueC-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 1.03A 3sueC-3s29A:
undetectable		 3sueC-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.92A 3sufA-3s29A:
undetectable		 3sufA-3s29A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.80A 3sufB-3s29A:
undetectable		 3sufB-3s29A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 0.92A 3sufB-3s29A:
undetectable		 3sufB-3s29A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 11 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.90A 3sufC-3s29A:
undetectable		 3sufC-3s29A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.93A 3sufD-3s29A:
undetectable		 3sufD-3s29A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.94A 3sugA-3s29A:
undetectable		 3sugA-3s29A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 LEU A 184
HIS A 187
MET A 195
 None
 0.89A 3thrD-3s29A:
2.4		 3thrD-3s29A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 6 ILE A  43
VAL A  86
LEU A  88
ILE A  80
 None
 0.88A 4asdA-3s29A:
undetectable		 4asdA-3s29A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 8 TYR A 658
VAL A 681
TYR A 533
ILE A 749
 None
 1.30A 4bqtC-3s29A:
undetectable
4bqtD-3s29A:
undetectable		 4bqtC-3s29A:
12.27
4bqtD-3s29A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 LYS A 618
PRO A 299
LYS A 615
 None
 1.46A 4dr6L-3s29A:
undetectable		 4dr6L-3s29A:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 5 HIS A 499
GLN A 495
GLY A 494
SER A 498
 None
 0.82A 4fu8A-3s29A:
undetectable		 4fu8A-3s29A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 8 GLY A 158
ASN A 522
PRO A 149
ILE A 155
 None
 0.96A 4j4vC-3s29A:
undetectable		 4j4vC-3s29A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 ARG A 382
HIS A 287
SER A 381
 FRU  A 902 (-4.1A)
FRU  A 902 (-4.0A)
None
 0.94A 4mjwA-3s29A:
2.0
4mjwB-3s29A:
undetectable		 4mjwA-3s29A:
22.13
4mjwB-3s29A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 SER A 381
ARG A 382
HIS A 287
 None
FRU  A 902 (-4.1A)
FRU  A 902 (-4.0A)
 0.98A 4mjwA-3s29A:
2.0
4mjwB-3s29A:
undetectable		 4mjwA-3s29A:
22.13
4mjwB-3s29A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 7 PHE A 117
THR A 503
ILE A 450
ASP A 449
 None
 0.97A 4pcuA-3s29A:
undetectable		 4pcuA-3s29A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 9 THR A 475
ALA A 471
ALA A 467
ILE A 411
ASP A 417
 None
 1.18A 4qvqK-3s29A:
undetectable
4qvqL-3s29A:
undetectable		 4qvqK-3s29A:
14.49
4qvqL-3s29A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 9 THR A 475
ALA A 471
ALA A 467
ILE A 411
ASP A 417
 None
 1.18A 4qvqY-3s29A:
undetectable
4qvqZ-3s29A:
undetectable		 4qvqY-3s29A:
14.49
4qvqZ-3s29A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 THR A 393
ALA A 396
GLU A 399
LEU A 284
PRO A 408
 None
 1.27A 4xi3D-3s29A:
undetectable		 4xi3D-3s29A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 5 GLU A 403
THR A 393
HIS A 427
LEU A 429
 None
 1.22A 5axaA-3s29A:
undetectable		 5axaA-3s29A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 5 GLU A 403
THR A 393
HIS A 427
LEU A 429
 None
 1.25A 5axaC-3s29A:
undetectable		 5axaC-3s29A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 6 GLU A 235
GLY A 327
ASP A 244
GLY A 241
 None
 0.88A 5cdnA-3s29A:
undetectable
5cdnB-3s29A:
2.1		 5cdnA-3s29A:
20.39
5cdnB-3s29A:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 6 GLY A  95
ASP A 138
ILE A 469
TYR A  99
 None
 1.13A 5iwuA-3s29A:
undetectable		 5iwuA-3s29A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 ALA A 721
LEU A 724
ALA A 725
PHE A 728
THR A 729
 None
 0.41A 5k9dA-3s29A:
undetectable		 5k9dA-3s29A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 LEU A 724
ALA A 725
PHE A 728
THR A 729
THR A 598
 None
 0.97A 5k9dA-3s29A:
undetectable		 5k9dA-3s29A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 LYS A  41
GLN A  48
ASN A  47
 None
 1.06A 5l2tA-3s29A:
undetectable		 5l2tA-3s29A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 ASN A 294
TYR A 298
CYH A 349
 None
 0.95A 5lsuB-3s29A:
undetectable		 5lsuB-3s29A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 ALA A 684
GLN A 670
THR A 691
 None
 0.69A 5n0oA-3s29A:
undetectable		 5n0oA-3s29A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 11 LEU A 337
GLY A 418
LEU A 365
THR A 393
ALA A 396
 None
 1.11A 5o96A-3s29A:
undetectable
5o96B-3s29A:
undetectable		 5o96A-3s29A:
14.96
5o96B-3s29A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 10 GLY A 303
HIS A 438
LYS A 585
GLU A 675
GLY A 678
 UDP  A 901 ( 2.9A)
None
UDP  A 901 (-2.8A)
UDP  A 901 (-4.1A)
UDP  A 901 ( 3.7A)
 0.57A 5vncC-3s29A:
15.3		 5vncC-3s29A:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_A_ASCA501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 10 TYR A 758
ILE A 308
GLN A 311
HIS A 438
ILE A 479
 None
 1.45A 5zovA-3s29A:
0.0		 5zovA-3s29A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 TYR A 715
ASN A 586
LEU A 673
 None
 0.83A 6b58A-3s29A:
1.3		 6b58A-3s29A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 GLY A 288
TYR A 392
PRO A 408
VAL A 295
GLY A 302
 None
None
None
None
FRU  A 902 ( 2.2A)
 1.43A 6gngA-3s29A:
16.4		 6gngA-3s29A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 GLY A 303
HIS A 438
ARG A 580
GLU A 675
GLY A 678
 UDP  A 901 ( 2.9A)
None
FRU  A 902 ( 3.7A)
UDP  A 901 (-4.1A)
UDP  A 901 ( 3.7A)
 0.61A 6gngA-3s29A:
16.4		 6gngA-3s29A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 4 LYS A 169
LEU A 166
ALA A 168
LEU A 268
 None
 1.30A 6gnrA-3s29A:
undetectable		 6gnrA-3s29A:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 4 LYS A 169
LEU A 166
ALA A 168
LEU A 268
 None
 1.31A 6gnrB-3s29A:
undetectable		 6gnrB-3s29A:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 5 LEU A 765
TYR A 769
ILE A 469
GLY A 158
 None
 1.01A 6hd6A-3s29A:
undetectable		 6hd6A-3s29A:
7.20