SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s2g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 ARG A 328
GLY A  14
ASP A  50
 None
 0.49A 1kf6A-3s2gA:
2.9
1kf6B-3s2gA:
undetectable		 1kf6A-3s2gA:
21.72
1kf6B-3s2gA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.78A 1muiB-3s2gA:
undetectable		 1muiB-3s2gA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 GLY A  88
ALA A 130
THR A 116
HIS A  65
GLY A  64
 None
None
None
ZN  A 500 ( 3.3A)
None
 1.17A 1utdE-3s2gA:
undetectable
1utdF-3s2gA:
undetectable		 1utdE-3s2gA:
11.25
1utdF-3s2gA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 11 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.84A 2aquB-3s2gA:
undetectable		 2aquB-3s2gA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 11 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.78A 2fxeB-3s2gA:
undetectable		 2fxeB-3s2gA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 MET A   5
PRO A  23
ALA A  15
PHE A  61
ILE A  62
 None
 1.19A 2jjpA-3s2gA:
undetectable		 2jjpA-3s2gA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.67A 2o4sA-3s2gA:
undetectable		 2o4sA-3s2gA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.84A 2r5pB-3s2gA:
undetectable		 2r5pB-3s2gA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 VAL A 185
ILE A 177
GLY A 178
GLY A 179
VAL A 308
 None
None
None
SO4  A 701 (-3.0A)
None
 1.00A 2r5pC-3s2gA:
undetectable		 2r5pC-3s2gA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.84A 2r5pD-3s2gA:
undetectable		 2r5pD-3s2gA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 11 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.88A 2r5qB-3s2gA:
undetectable		 2r5qB-3s2gA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 SER A  39
GLY A 125
GLY A 122
 None
 0.40A 3bogA-3s2gA:
undetectable
3bogC-3s2gA:
undetectable		 3bogA-3s2gA:
undetectable
3bogC-3s2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 GLY A 123
GLY A 117
GLY A  64
 None
 0.44A 3bogC-3s2gA:
undetectable		 3bogC-3s2gA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.82A 3bvbA-3s2gA:
undetectable		 3bvbA-3s2gA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.69A 3d1xA-3s2gA:
undetectable		 3d1xA-3s2gA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.82A 3d1yA-3s2gA:
undetectable		 3d1yA-3s2gA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 11 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.93A 3em4A-3s2gA:
undetectable		 3em4A-3s2gA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 GLU A  66
VAL A  41
CYH A  42
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-2.5A)
 1.06A 3fbxA-3s2gA:
0.4		 3fbxA-3s2gA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.82A 3k4vA-3s2gA:
undetectable		 3k4vA-3s2gA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.83A 3ndtA-3s2gA:
undetectable		 3ndtA-3s2gA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.80A 3ndtB-3s2gA:
undetectable		 3ndtB-3s2gA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 11 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.88A 3ndxB-3s2gA:
undetectable		 3ndxB-3s2gA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.87A 3nu5A-3s2gA:
undetectable		 3nu5A-3s2gA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.85A 3tl9A-3s2gA:
undetectable		 3tl9A-3s2gA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A 123
GLY A  64
ILE A  36
ASN A 121
VAL A 128
 None
 1.11A 4fr0A-3s2gA:
5.9		 4fr0A-3s2gA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A 123
LEU A 151
ILE A  36
ASN A 121
VAL A 128
 None
 1.12A 4fr0A-3s2gA:
5.9		 4fr0A-3s2gA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A 136
LEU A 151
VAL A 290
HIS A  65
THR A 116
 None
None
FU2  A 600 (-4.4A)
ZN  A 500 ( 3.3A)
None
 1.33A 4ojbA-3s2gA:
undetectable		 4ojbA-3s2gA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A 136
LEU A 151
VAL A 290
HIS A  65
THR A 116
 None
None
FU2  A 600 (-4.4A)
ZN  A 500 ( 3.3A)
None
 1.31A 4okxA-3s2gA:
undetectable		 4okxA-3s2gA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 GLN A 170
HIS A 236
ARG A 256
 None
 1.05A 4qyqA-3s2gA:
undetectable		 4qyqA-3s2gA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 GLN A 170
HIS A 236
ARG A 256
 None
 0.99A 4qyqB-3s2gA:
undetectable		 4qyqB-3s2gA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 THR A 156
GLY A 265
ASN A 264
LEU A  46
ALA A  48
 None
 1.02A 4uckB-3s2gA:
3.4		 4uckB-3s2gA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 THR A 311
GLY A 181
GLY A 179
ALA A 216
ALA A 208
 None
None
SO4  A 701 (-3.0A)
None
None
 1.11A 4uckB-3s2gA:
3.4		 4uckB-3s2gA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 ALA A 196
TRP A 171
VAL A 172
 None
 0.43A 4w9nC-3s2gA:
27.8		 4w9nC-3s2gA:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 SER A  39
LEU A 338
VAL A   9
ILE A  62
GLY A 122
 None
 1.02A 4y8wC-3s2gA:
undetectable		 4y8wC-3s2gA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 LEU A 266
LEU A 161
THR A 241
GLY A 181
ILE A 174
 None
 0.97A 5d4uD-3s2gA:
6.9		 5d4uD-3s2gA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 GLY A  64
GLY A  88
ALA A 130
THR A 116
HIS A  65
 None
None
None
None
ZN  A 500 ( 3.3A)
 1.17A 5eevA-3s2gA:
undetectable
5eevB-3s2gA:
undetectable		 5eevA-3s2gA:
11.25
5eevB-3s2gA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 GLY A  64
GLY A  88
ALA A 130
THR A 116
HIS A  65
 None
None
None
None
ZN  A 500 ( 3.3A)
 1.17A 5eexA-3s2gA:
undetectable
5eexB-3s2gA:
undetectable		 5eexA-3s2gA:
11.25
5eexB-3s2gA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 GLY A  64
GLY A  88
ALA A 130
THR A 116
HIS A  65
 None
None
None
None
ZN  A 500 ( 3.3A)
 1.17A 5eeyA-3s2gA:
undetectable
5eeyB-3s2gA:
undetectable		 5eeyA-3s2gA:
11.25
5eeyB-3s2gA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 GLY A  64
GLY A  88
ALA A 130
THR A 116
HIS A  65
 None
None
None
None
ZN  A 500 ( 3.3A)
 1.17A 5eezA-3s2gA:
undetectable
5eezB-3s2gA:
undetectable		 5eezA-3s2gA:
11.25
5eezB-3s2gA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 GLY A  64
GLY A  88
ALA A 130
THR A 116
HIS A  65
 None
None
None
None
ZN  A 500 ( 3.3A)
 1.17A 5ef0A-3s2gA:
undetectable
5ef0B-3s2gA:
undetectable		 5ef0A-3s2gA:
11.25
5ef0B-3s2gA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 GLY A  64
GLY A  88
ALA A 130
THR A 116
HIS A  65
 None
None
None
None
ZN  A 500 ( 3.3A)
 1.17A 5ef1A-3s2gA:
undetectable
5ef1B-3s2gA:
undetectable		 5ef1A-3s2gA:
11.25
5ef1B-3s2gA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 GLY A  64
GLY A  88
ALA A 130
THR A 116
HIS A  65
 None
None
None
None
ZN  A 500 ( 3.3A)
 1.17A 5ef2A-3s2gA:
undetectable
5ef2B-3s2gA:
undetectable		 5ef2A-3s2gA:
11.25
5ef2B-3s2gA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 GLY A  64
GLY A  88
ALA A 130
THR A 116
HIS A  65
 None
None
None
None
ZN  A 500 ( 3.3A)
 1.17A 5ef3A-3s2gA:
undetectable
5ef3B-3s2gA:
undetectable		 5ef3A-3s2gA:
11.25
5ef3B-3s2gA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.78A 5kqxA-3s2gA:
undetectable		 5kqxA-3s2gA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		4 / 4 GLU A 107
THR A 108
THR A 116
LEU A 151
 None
 1.42A 5v96A-3s2gA:
10.6		 5v96A-3s2gA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		4 / 4 GLU A 107
THR A 108
THR A 116
LEU A 151
 None
 1.44A 5v96B-3s2gA:
10.8		 5v96B-3s2gA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		4 / 4 GLU A 107
THR A 108
THR A 116
LEU A 151
 None
 1.44A 5v96C-3s2gA:
5.6		 5v96C-3s2gA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		4 / 4 GLU A 107
THR A 108
THR A 116
LEU A 151
 None
 1.42A 5v96D-3s2gA:
10.7		 5v96D-3s2gA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 ASP A 221
ASN A 218
ASP A 201
 None
 0.84A 5vopA-3s2gA:
undetectable		 5vopA-3s2gA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 ASP A 221
ASN A 218
ASP A 201
 None
 0.86A 5vopB-3s2gA:
undetectable		 5vopB-3s2gA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 ASN A 321
LEU A  46
GLY A  14
ASP A  52
LEU A  17
 None
 0.89A 6ectA-3s2gA:
5.2		 6ectA-3s2gA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3s2g ZINC-CONTAINING
ALCOHOL
DEHYDROGENASE
SUPERFAMILY
(Cupriavidus
pinatubonensis) 		5 / 10 TRP A  53
SER A 288
GLY A 287
LEU A 266
GLY A 265
 None
 1.42A 6hqbA-3s2gA:
undetectable
6hqbJ-3s2gA:
undetectable		 6hqbA-3s2gA:
13.89
6hqbJ-3s2gA:
7.08