SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s2u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  20
GLU A 267
LEU A 263
GLY A 100
LEU A  99
 None
UD1  A 366 (-2.6A)
UD1  A 366 (-3.8A)
None
None
 1.04A 1g50B-3s2uA:
undetectable		 1g50B-3s2uA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  20
GLU A 267
LEU A 263
GLY A 100
LEU A  99
 None
UD1  A 366 (-2.6A)
UD1  A 366 (-3.8A)
None
None
 1.04A 1g50C-3s2uA:
undetectable		 1g50C-3s2uA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 277
PRO A 279
LEU A 303
ARG A 297
 None
 1.23A 1hrkB-3s2uA:
4.3		 1hrkB-3s2uA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 216
LEU A 199
ALA A 202
LEU A 203
 None
 1.04A 1hwiB-3s2uA:
undetectable		 1hwiB-3s2uA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 9 HIS A 216
LEU A 199
ALA A 202
LEU A 203
LEU A 318
 None
 1.29A 1hwiA-3s2uA:
undetectable		 1hwiA-3s2uA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 7 GLN A 123
GLU A 122
MET A   8
ALA A   9
 None
 1.28A 1linA-3s2uA:
undetectable		 1linA-3s2uA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 9 TYR A 230
LEU A 318
LEU A 183
VAL A 235
ALA A 234
 None
 1.23A 1tbfA-3s2uA:
undetectable		 1tbfA-3s2uA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  99
GLY A  10
ILE A 120
GLY A 101
GLY A 100
 None
 0.86A 1uakA-3s2uA:
undetectable		 1uakA-3s2uA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  47
LEU A  46
LEU A  52
GLY A  10
ALA A   9
 None
 1.08A 2aylB-3s2uA:
undetectable		 2aylB-3s2uA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A   7
HIS A 121
ALA A 355
CYH A 351
VAL A 347
 None
 1.31A 2g72B-3s2uA:
2.5		 2g72B-3s2uA:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 277
PRO A 279
LEU A 303
ARG A 297
 None
 1.15A 2hrcA-3s2uA:
undetectable		 2hrcA-3s2uA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 277
PRO A 279
LEU A 303
ARG A 297
 None
 1.21A 2hrcB-3s2uA:
4.5		 2hrcB-3s2uA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 277
PRO A 279
LEU A 303
ARG A 297
 None
 1.24A 2pnjB-3s2uA:
2.5		 2pnjB-3s2uA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  52
ASP A  45
ILE A  42
GLY A  11
GLY A  10
 None
 1.01A 2r5pA-3s2uA:
undetectable		 2r5pA-3s2uA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  52
ASP A  45
ILE A  42
GLY A  11
GLY A  10
 None
 1.01A 2r5pC-3s2uA:
undetectable		 2r5pC-3s2uA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  10
GLY A  37
ILE A 120
GLY A 101
GLY A 100
 None
 0.85A 3axzA-3s2uA:
undetectable		 3axzA-3s2uA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  99
GLY A  10
GLY A  37
GLY A 101
GLY A 100
 None
 0.97A 3axzA-3s2uA:
undetectable		 3axzA-3s2uA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 187
GLY A 219
GLY A 191
 None
 0.43A 3bogD-3s2uA:
undetectable		 3bogD-3s2uA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A  45
ILE A  42
GLY A  11
GLY A  10
PRO A  18
 None
 0.86A 3cyxB-3s2uA:
undetectable		 3cyxB-3s2uA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 6 PRO A  53
HIS A  55
LEU A  91
ALA A  32
 None
 1.09A 3gv1A-3s2uA:
undetectable
3gv1C-3s2uA:
2.2		 3gv1A-3s2uA:
16.71
3gv1C-3s2uA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  91
ALA A  32
PRO A  53
HIS A  55
 None
 1.06A 3gv1A-3s2uA:
undetectable
3gv1B-3s2uA:
1.7		 3gv1A-3s2uA:
16.71
3gv1B-3s2uA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 277
PRO A 279
LEU A 303
ARG A 297
 None
 1.19A 3hcoB-3s2uA:
4.4		 3hcoB-3s2uA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A  43
THR A 104
GLY A 100
ALA A   9
GLY A  11
 None
 1.05A 3tegA-3s2uA:
undetectable		 3tegA-3s2uA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  20
GLU A 267
LEU A 263
GLY A 100
LEU A  99
 None
UD1  A 366 (-2.6A)
UD1  A 366 (-3.8A)
None
None
 1.15A 3uudA-3s2uA:
undetectable		 3uudA-3s2uA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 166
ALA A 253
ILE A 243
LEU A 186
VAL A 256
 None
None
UD1  A 366 (-4.0A)
None
None
 1.06A 3w67C-3s2uA:
undetectable		 3w67C-3s2uA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 261
VAL A 265
THR A 264
LEU A 263
ASN A 160
 UD1  A 366 (-3.2A)
None
UD1  A 366 (-2.8A)
UD1  A 366 (-3.8A)
None
 1.01A 4f84A-3s2uA:
4.0		 4f84A-3s2uA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 107
GLY A 105
ILE A  57
ALA A 110
ARG A  86
 None
 1.12A 4qtuD-3s2uA:
3.7		 4qtuD-3s2uA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 9 VAL A  47
LEU A  46
LEU A  52
GLY A  10
ALA A   9
 None
 1.00A 4rs0A-3s2uA:
undetectable		 4rs0A-3s2uA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ASN A 131
GLY A 107
ALA A 111
ALA A 138
VAL A 141
 None
 1.10A 4ryaA-3s2uA:
undetectable		 4ryaA-3s2uA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A  37
THR A  38
GLY A 101
GLU A  43
 None
 0.94A 4v20A-3s2uA:
undetectable		 4v20A-3s2uA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  81
ALA A 111
ASN A 114
ILE A  88
 None
 1.09A 4y03B-3s2uA:
undetectable		 4y03B-3s2uA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		6 / 12 LEU A  99
GLY A  10
GLY A  37
ILE A 120
GLY A 101
GLY A 100
 None
 0.96A 4yvgA-3s2uA:
undetectable		 4yvgA-3s2uA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  36
VAL A  87
ILE A  88
LEU A 134
LEU A 118
 None
 1.02A 4yvpB-3s2uA:
undetectable		 4yvpB-3s2uA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 128
ILE A 120
LEU A 134
GLY A 100
GLY A 261
 None
None
None
None
UD1  A 366 (-3.2A)
 0.87A 5d4uC-3s2uA:
5.6		 5d4uC-3s2uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 128
ILE A 120
LEU A 134
GLY A 100
GLY A 261
 None
None
None
None
UD1  A 366 (-3.2A)
 0.89A 5d4uD-3s2uA:
undetectable		 5d4uD-3s2uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 119
ARG A 140
LEU A 156
THR A 158
 None
 0.88A 5e4dA-3s2uA:
undetectable
5e4dB-3s2uA:
undetectable		 5e4dA-3s2uA:
19.20
5e4dB-3s2uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5H_A_ACTA1229_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 4 VAL A 141
GLU A 122
THR A 148
GLU A 143
 None
 1.45A 5g5hA-3s2uA:
0.0		 5g5hA-3s2uA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A   9
GLY A 101
GLY A  14
ARG A 163
GLY A  37
 None
None
UD1  A 366 (-3.1A)
UD1  A 366 (-3.4A)
None
 0.99A 5gwxA-3s2uA:
4.3		 5gwxA-3s2uA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		3 / 3 VAL A   5
TYR A  31
GLN A  27
 None
 0.75A 5qgkA-3s2uA:
undetectable		 5qgkA-3s2uA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 MET A 331
GLN A 334
ALA A 335
VAL A 265
PHE A 145
 None
 1.28A 5vlmG-3s2uA:
undetectable		 5vlmG-3s2uA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  10
GLY A  37
ILE A 120
GLY A 101
GLY A 100
 None
 0.89A 5wyqA-3s2uA:
undetectable		 5wyqA-3s2uA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  99
GLY A  10
GLY A  37
GLY A 101
GLY A 100
 None
 0.91A 5wyqA-3s2uA:
undetectable		 5wyqA-3s2uA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  99
GLY A  10
ILE A 120
GLY A 101
GLY A 100
 None
 0.84A 5wyqB-3s2uA:
undetectable		 5wyqB-3s2uA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 187
LEU A 186
GLN A 217
ALA A 240
 None
None
UD1  A 366 (-3.6A)
None
 0.81A 5xu8A-3s2uA:
undetectable		 5xu8A-3s2uA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		6 / 12 LEU A  99
GLY A  10
GLY A  37
ILE A 120
GLY A 101
GLY A 100
 None
 0.95A 5zhmB-3s2uA:
undetectable		 5zhmB-3s2uA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 THR A 148
PHE A 149
ALA A 135
THR A 104
ALA A   9
 None
 1.36A 6efnA-3s2uA:
undetectable		 6efnA-3s2uA:
22.48