SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 7 HIS A 314
THR A 320
TYR A 253
LEU A 368
 None
 1.08A 1qzrA-3s30A:
undetectable		 1qzrA-3s30A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 7 HIS A 314
THR A 320
TYR A 253
LEU A 368
 None
 1.07A 1qzrB-3s30A:
undetectable		 1qzrB-3s30A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 THR A 191
GLY A 189
ASN A 133
LEU A 375
VAL A 376
 None
 1.07A 1r30A-3s30A:
undetectable		 1r30A-3s30A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 THR A 191
GLY A 189
ASN A 133
LEU A 375
VAL A 376
 None
 1.07A 1r30B-3s30A:
undetectable		 1r30B-3s30A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 11 LEU A 290
ASP A 291
GLY A 292
TYR A 299
TYR A 277
 None
 1.37A 1s9aA-3s30A:
undetectable		 1s9aA-3s30A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 290
ASP A 291
GLY A 292
TYR A 299
TYR A 277
 None
 1.37A 1s9aB-3s30A:
undetectable		 1s9aB-3s30A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 GLY A 251
LEU A 324
ASP A 372
LEU A 351
LEU A 218
 None
None
NA  A 383 ( 4.6A)
None
None
 0.95A 3cjtO-3s30A:
undetectable		 3cjtO-3s30A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 9 TYR A 277
LEU A 233
VAL A 350
LEU A 197
VAL A 359
 None
 1.50A 3jwqA-3s30A:
undetectable		 3jwqA-3s30A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_D_ACTD1113_0
(BLR5658 PROTEIN)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 4 TRP A 162
LEU A 351
LEU A 197
THR A 183
 None
 1.10A 4bboD-3s30A:
undetectable		 4bboD-3s30A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 7 PHE A 326
TYR A 328
ILE A 335
PRO A 246
 None
 0.86A 4g5jA-3s30A:
undetectable		 4g5jA-3s30A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 LEU A 150
SER A 163
LEU A 160
LEU A 195
 None
 1.24A 4n09B-3s30A:
undetectable		 4n09B-3s30A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 LEU A 150
SER A 163
LEU A 160
LEU A 195
 None
 1.25A 4n09D-3s30A:
undetectable		 4n09D-3s30A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		6 / 12 ILE A 335
PHE A 326
GLY A 332
ALA A 278
PRO A 246
LEU A 375
 None
 1.06A 5e72A-3s30A:
undetectable		 5e72A-3s30A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 VAL A 350
TYR A 277
MET A 304
ILE A 294
 None
 1.20A 5iwuA-3s30A:
undetectable		 5iwuA-3s30A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 GLY A 357
PHE A 274
TYR A 299
ALA A 295
VAL A 350
 None
 1.27A 5n0xB-3s30A:
undetectable		 5n0xB-3s30A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_B_SAMB503_0
(CARNOSINE
N-METHYLTRANSFERASE)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 GLY A 168
ASN A 166
PHE A 181
THR A 172
TYR A 176
 None
 1.44A 5yf0B-3s30A:
undetectable		 5yf0B-3s30A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3s30 HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 GLY A 216
GLY A 165
ALA A 232
ASP A 291
PHE A 238
 None
 1.08A 6nj9K-3s30A:
undetectable		 6nj9K-3s30A:
23.26