SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s35'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3s35 6.64 FAB HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		5 / 11 LEU H  11
GLY H   8
GLU H  10
PRO H 204
HIS H 203
 None
 1.15A 1p91A-3s35H:
undetectable		 1p91A-3s35H:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3s35 6.64 FAB HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 THR H 114
GLU H 152
HIS H 203
 None
 0.74A 3g1uB-3s35H:
undetectable		 3g1uB-3s35H:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 3s35 6.64 FAB HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 HIS H  99
HIS H  35
ILE H  33
 None
 0.68A 3u52A-3s35H:
undetectable
3u52C-3s35H:
undetectable		 3u52A-3s35H:
19.60
3u52C-3s35H:
19.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WFH_B_P2EB301_1
(MAB FAB H FRAGMENT
MAB FAB L FRAGMENT)		 3s35 6.64 FAB HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		5 / 12 HIS H  35
VAL H  37
TRP H  50
HIS H  99
TRP H 107
 None
 1.13A 3wfhA-3s35H:
28.0
3wfhB-3s35H:
18.8		 3wfhA-3s35H:
88.94
3wfhB-3s35H:
26.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WHX_B_XPGB301_1
(MAB FAB H FRAGMENT
MAB FAB L FRAGMENT)		 3s35 6.64 FAB HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		5 / 12 HIS H  35
VAL H  37
TRP H  50
HIS H  99
TRP H 107
 None
 1.14A 3whxA-3s35H:
28.0
3whxB-3s35H:
18.7		 3whxA-3s35H:
88.94
3whxB-3s35H:
26.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3s35 6.64 FAB HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 106
 None
 0.31A 4m7kH-3s35H:
23.5		 4m7kH-3s35H:
65.16