SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		4 / 7 HIS B 114
LEU B  84
SER B 109
ASP B 111
 CUA  B 802 (-3.0A)
None
None
None
 1.25A 1ismB-3s38B:
undetectable		 1ismB-3s38B:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		5 / 9 GLY B 115
ILE B 107
ALA B  85
VAL B  83
PHE B 105
 None
 1.10A 2drdA-3s38B:
undetectable		 2drdA-3s38B:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1598_0
(NITROUS OXIDE
REDUCTASE)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		4 / 4 HIS B 114
CYH B 149
CYH B 153
MET B 160
 CUA  B 802 (-3.0A)
CUA  B 802 (-1.9A)
CUA  B 802 (-2.0A)
CUA  B 802 (-2.0A)
 0.47A 2iwkA-3s38B:
11.7		 2iwkA-3s38B:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		3 / 3 CYH B 149
CYH B 153
HIS B 157
 CUA  B 802 (-1.9A)
CUA  B 802 (-2.0A)
CUA  B 802 (-2.7A)
 0.41A 2iwkA-3s38B:
11.7		 2iwkA-3s38B:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1598_0
(NITROUS OXIDE
REDUCTASE)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		4 / 4 HIS B 114
CYH B 149
CYH B 153
MET B 160
 CUA  B 802 (-3.0A)
CUA  B 802 (-1.9A)
CUA  B 802 (-2.0A)
CUA  B 802 (-2.0A)
 0.47A 2iwkB-3s38B:
13.9		 2iwkB-3s38B:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		3 / 3 CYH B 149
CYH B 153
HIS B 157
 CUA  B 802 (-1.9A)
CUA  B 802 (-2.0A)
CUA  B 802 (-2.7A)
 0.41A 2iwkB-3s38B:
13.9		 2iwkB-3s38B:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		4 / 5 PRO B  94
ILE B  95
PRO B  92
TYR B  90
 None
 1.25A 3d9lA-3s38B:
undetectable
3d9lY-3s38B:
undetectable		 3d9lA-3s38B:
23.63
3d9lY-3s38B:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1004_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		4 / 4 HIS B 114
CYH B 149
CYH B 153
MET B 160
 CUA  B 802 (-3.0A)
CUA  B 802 (-1.9A)
CUA  B 802 (-2.0A)
CUA  B 802 (-2.0A)
 0.58A 3dtuB-3s38B:
9.3		 3dtuB-3s38B:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		3 / 3 CYH B 149
CYH B 153
HIS B 157
 CUA  B 802 (-1.9A)
CUA  B 802 (-2.0A)
CUA  B 802 (-2.7A)
 0.38A 3dtuB-3s38B:
9.3		 3dtuB-3s38B:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		3 / 3 CYH B 149
CYH B 153
HIS B 157
 CUA  B 802 (-1.9A)
CUA  B 802 (-2.0A)
CUA  B 802 (-2.7A)
 0.36A 3dtuD-3s38B:
8.9		 3dtuD-3s38B:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD4_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		4 / 4 HIS B 114
CYH B 149
CYH B 153
MET B 160
 CUA  B 802 (-3.0A)
CUA  B 802 (-1.9A)
CUA  B 802 (-2.0A)
CUA  B 802 (-2.0A)
 0.58A 3dtuD-3s38B:
8.9		 3dtuD-3s38B:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		4 / 4 GLN B  99
PRO B  98
VAL B 166
GLU B  96
 None
 1.16A 3huoA-3s38B:
undetectable		 3huoA-3s38B:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		5 / 11 ILE B 107
PHE B 116
ILE B 103
PRO B  92
VAL B  71
 None
 1.10A 3tmzA-3s38B:
undetectable		 3tmzA-3s38B:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		5 / 12 PHE B 116
VAL B 125
ILE B 103
VAL B  97
VAL B 135
 None
 1.19A 6ap6A-3s38B:
undetectable		 6ap6A-3s38B:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		5 / 12 VAL B 125
PHE B 139
ILE B 103
VAL B  97
VAL B 135
 None
 1.33A 6ap6A-3s38B:
undetectable		 6ap6A-3s38B:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		5 / 12 PHE B 116
VAL B 125
ILE B 103
VAL B  97
VAL B 135
 None
 1.20A 6ap6B-3s38B:
undetectable		 6ap6B-3s38B:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		5 / 12 VAL B 125
PHE B 139
ILE B 103
VAL B  97
VAL B 135
 None
 1.31A 6ap6B-3s38B:
undetectable		 6ap6B-3s38B:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3s38 CYTOCHROME C OXIDASE
SUBUNIT 2
(Thermus
thermophilus) 		4 / 6 VAL B 166
ASN B  93
PRO B  94
ILE B  95
 None
 1.18A 6h7uA-3s38B:
undetectable		 6h7uA-3s38B:
15.67