SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3s4d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		3 / 3 GLN A  40
HIS A  39
PRO A  23
 None
 0.86A 1d8cA-3s4dA:
undetectable		 1d8cA-3s4dA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		3 / 3 GLN A 395
HIS A 463
PRO A 449
 None
 0.85A 1d8cA-3s4dA:
undetectable		 1d8cA-3s4dA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 4 GLY A  42
LEU A  37
GLY A  43
ARG A  70
 None
 1.27A 1j7kA-3s4dA:
undetectable		 1j7kA-3s4dA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 4 GLY A  42
LEU A  37
GLY A  69
ARG A  70
 None
 1.22A 1j7kA-3s4dA:
undetectable		 1j7kA-3s4dA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 10 SER A 183
SER A 248
PHE A 147
LEU A 146
VAL A 253
 None
 1.48A 1q23E-3s4dA:
undetectable		 1q23E-3s4dA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A 484
ASN A 493
LEU A 492
GLY A 476
ASP A 487
 None
 1.11A 2f8lA-3s4dA:
undetectable		 2f8lA-3s4dA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		3 / 3 THR A  56
SER A  45
PHE A 355
 None
 0.86A 3d4sA-3s4dA:
undetectable		 3d4sA-3s4dA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		3 / 3 GLN A 395
THR A 394
LEU A 373
 None
 0.64A 3ondA-3s4dA:
undetectable		 3ondA-3s4dA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		3 / 3 GLN A 395
THR A 394
LEU A 373
 None
 0.64A 3ondB-3s4dA:
undetectable		 3ondB-3s4dA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 8 ASP A 686
ASP A 764
PRO A 766
PRO A 763
 None
 1.12A 3oyaA-3s4dA:
undetectable		 3oyaA-3s4dA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 6 PRO A 245
SER A 235
VAL A 175
THR A 216
 None
 0.97A 3tneA-3s4dA:
undetectable		 3tneA-3s4dA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 7 ARG A  54
ALA A  50
MET A 349
ALA A 353
 None
 1.14A 3tx2A-3s4dA:
undetectable		 3tx2A-3s4dA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 5 THR A 145
GLY A 233
PRO A 230
ASN A  75
 None
 1.25A 3u8qA-3s4dA:
undetectable		 3u8qA-3s4dA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 PHE A 149
HIS A 249
GLY A 247
ALA A 228
ASN A 222
 None
 1.14A 3v3oB-3s4dA:
undetectable		 3v3oB-3s4dA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 8 ALA A 353
SER A 354
LEU A  36
TYR A  58
 None
 1.05A 4ijiF-3s4dA:
2.1		 4ijiF-3s4dA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.94A 4jksA-3s4dA:
undetectable		 4jksA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.93A 4jksB-3s4dA:
undetectable		 4jksB-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.94A 4jkuA-3s4dA:
undetectable		 4jkuA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.94A 4k8cA-3s4dA:
undetectable		 4k8cA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.93A 4k8cB-3s4dA:
undetectable		 4k8cB-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.93A 4k8kA-3s4dA:
undetectable		 4k8kA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.93A 4k8kB-3s4dA:
undetectable		 4k8kB-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.93A 4kahA-3s4dA:
undetectable		 4kahA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.94A 4kahB-3s4dA:
undetectable		 4kahB-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.93A 4kalA-3s4dA:
undetectable		 4kalA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.93A 4kalB-3s4dA:
undetectable		 4kalB-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.95A 4kanA-3s4dA:
undetectable		 4kanA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.95A 4kanB-3s4dA:
undetectable		 4kanB-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.95A 4kbeA-3s4dA:
undetectable		 4kbeA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.93A 4kbeB-3s4dA:
undetectable		 4kbeB-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.94A 4lbgA-3s4dA:
undetectable		 4lbgA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.94A 4lbgB-3s4dA:
undetectable		 4lbgB-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.92A 4lcaA-3s4dA:
undetectable		 4lcaA-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 GLY A  42
GLY A  69
SER A  84
ILE A 106
THR A  82
 None
 0.94A 4lcaB-3s4dA:
undetectable		 4lcaB-3s4dA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 ALA A 619
GLY A 602
LEU A 527
ALA A 616
TYR A 744
 None
 1.13A 4lg1B-3s4dA:
undetectable		 4lg1B-3s4dA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 ALA A 619
GLY A 602
LEU A 527
ALA A 616
TYR A 744
 None
 1.12A 4lg1C-3s4dA:
undetectable		 4lg1C-3s4dA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 8 TYR A 710
THR A 731
HIS A 703
PHE A   6
 None
SO4  A 823 (-3.6A)
None
None
 1.41A 4tzcB-3s4dA:
undetectable
4tzcD-3s4dA:
undetectable		 4tzcB-3s4dA:
8.22
4tzcD-3s4dA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 4 GLY A 171
VAL A 173
PHE A 217
ILE A 246
 None
 1.14A 4xv2B-3s4dA:
undetectable		 4xv2B-3s4dA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		3 / 3 GLU A 517
HIS A 478
ASP A 574
 None
 0.83A 5c0oG-3s4dA:
undetectable		 5c0oG-3s4dA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		5 / 12 LEU A 527
SER A 518
GLU A 593
PHE A 597
GLY A 596
 None
 1.37A 5il1A-3s4dA:
undetectable		 5il1A-3s4dA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 8 ARG A 188
GLU A 174
ASP A 280
TRP A 278
 None
 0.87A 5kf8A-3s4dA:
undetectable		 5kf8A-3s4dA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGJ_A_X6XA402_1
(PREDICTED
ACETYLTRANSFERASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 5 ARG A 188
GLU A 174
ASP A 280
TRP A 278
 None
 0.84A 5kgjA-3s4dA:
0.8		 5kgjA-3s4dA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 8 ARG A 188
GLU A 174
ASP A 280
TRP A 278
 None
 0.93A 5kgpA-3s4dA:
undetectable		 5kgpA-3s4dA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 8 ARG A 188
GLU A 174
ASP A 280
TRP A 278
 None
 0.97A 5kgpB-3s4dA:
undetectable		 5kgpB-3s4dA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 5 VAL A 251
THR A 205
ASN A 204
LEU A 263
 None
 1.30A 5m0iB-3s4dA:
undetectable		 5m0iB-3s4dA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 4 ASN A 495
SER A 518
ALA A 516
VAL A 515
 None
 1.10A 5nm5A-3s4dA:
undetectable		 5nm5A-3s4dA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 7 PHE A 597
TRP A 488
ASP A 422
SER A 518
 None
CBI  A 824 (-2.7A)
None
None
 1.37A 5nr3A-3s4dA:
undetectable		 5nr3A-3s4dA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		3 / 3 GLY A 479
LEU A 480
HIS A 478
 None
 0.69A 5u63A-3s4dA:
undetectable		 5u63A-3s4dA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 7 VAL A 264
VAL A 129
LYS A 131
ASP A 305
 None
 0.84A 5yf9B-3s4dA:
undetectable		 5yf9B-3s4dA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 6 ARG A 571
ILE A 590
GLN A 636
ILE A 580
 None
 1.21A 6cbdA-3s4dA:
undetectable		 6cbdA-3s4dA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3s4d LACTOSE
PHOSPHORYLASE
(Cellulomonas
uda) 		4 / 6 VAL A 741
ASN A 668
PRO A 669
ILE A 672
 None
 1.04A 6h7uA-3s4dA:
undetectable		 6h7uA-3s4dA:
20.24